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Claire Bastie

Job Title
Associate Professor
Department
WMS - Translational Medicine
Phone
02476 151 202
Research Interests

The overall research interest of the lab is the regulation of nutrient sensing pathways in health and disease, with an emphasis on the metabolic changes related to obesity and type 2 diabetes. We have uncovered that Fyn tyrosine kinase is a nutrient-sensor regulating whole body energy homeostasis in conditions of excess (obesity) or deprivation (caloric restriction) of nutrient availability. Specific interests include: 1. Exploring how Fyn regulates adipose tissue development and differentiation, also investigating the relevance of Fyn function in obese individuals 2. Examining how Fyn relays nutritional signals between mother and foetus in pregnancies complicated with obesity and/or gestational diabetes.

Biography

I am an Associate Professor in Metabolic Biochemistry. Following a Ph.D at INSERM in the Centre of Biochemistry at Nice-Sophia-Antipolis (France), I moved as a Post-Doctoral fellow then as a Research Instructor at the State University of New York (USA). In 2010, I started my own lab at Albert Einstein College of Medicine (AECOM) in New York, supported by the National Institutes of Health. I held a joint appointment at AECOM and Warwick Medical School from 2011 to 2015 before permanently moving to Warwick Medical School.