The Sampath laboratory is interested in understanding how embryonic development and differentiation are controlled. We investigate the molecular functions of factors that participate in these processes using zebrafish embryos as the primary experimental system. In particular, we are investigating the roles and regulation of RNA and protein factors in early development. We combine live imaging, proteomic, genetic, genomic, and cell & developmental approaches (Tran et al., Development 2012, Kumari et al., eLife, 2013; Lim et al., Genome Biology, 2013; Wang et al., eLife 2016; Zaucker et al., NAR, 2018; Vong et al., 2020). Our current research focuses on the following themes: 1) Regulation of Nodal signalling 2) Cytoskeletal organisation and function 3) RNA elements in development and disease

Karuna Sampath is a Professor of Biomedicine, University of Warwick. Following her doctoral training at Indiana State University, USA with Gary Stuart, she did brief post-doctoral stints with Christopher Wright at Vanderbilt University, Nashville, USA (1995-1996), and Vladimir Korzh at the Institute of Molecular Agrobiology, Singapore (1997-1998). She was a visiting scientist at EMBL (host: Anne Ephrussi) in 1999, and started her independent programme in 2000 as a fellow at the Institute of Molecular Agrobiology, Singapore. She was a group leader at Temasek Life Sciences Laboratory, National University of Singapore from 2002-2013. The Sampath lab is located on the Gibbett Hill campus of the University of Warwick. The group is funded by Warwick Medical School, Warwick Quantitative Biomedicine Programme, the BBSRC and the Leverhulme Trust. Karuna Sampath serves on the board of the European Zebrafish society and the International Zebrafish society.