Broken Heart Syndrome
Esther Knights (History)
Can Heartbreak be Lethal?
Takotsubo Cardiomyopathy, or 'broken heart syndrome', is a condition where the heart suddenly changes shape and is weakened. The syndrome’s association with a broken heart is because it often appears to be triggered by emotionally or physically stressful events, with women who have heard distressing news being particularly vulnerable. Its name, 'Takotsubo', originated because when the syndrome was first observed in Japan in 1990, the left ventricle (as shown in picture A) resembled the shape of Japanese Octopus pots, which are called ‘takotsubos’ (as shown in picture B). Whilst there is a long history of the heart being seen as vulnerable, the details of this syndrome are still emerging. This Cabinet, placed in the Postgraduate Private Study area, shows an ongoing development in the history of heartbreak in modernity.
Further Reading
Books
Chiles, Christopher D, Patel, Rikin; Baggett, Charles, Netter’s Cardiology, (Philadelphia: Elsevier, 1 January 2019), pp. 235-238.
Kaddoura, Sam, Echo Made Easy (Elsevier, 2025), pp. 62-119.
Shen, Jasmine, Crash Course Cardiology (Elsevier, Jan 2025), pp. 203-12.
Stamp, Nikki, Can You Die of a Broken Heart? (London, Sydney: Murdoch Books, 2018), pp. 18-39.
Chapters
Mitsuma W et al, ‘Takotsubo Cardiomyopathy’ in Charles, Fred H.D., MD, MPH; Afari, Maxwell Eyram, MD, Ferri's Clinical Advisor 2026 (Philadelphia: Elsevier Inc, 2026).
Articles
Templin, Christian, Ghadri, Diekmann, Jelena R., Johanna, et al. “Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy”, New England Journal of Medicine, Vol. 373, No. 10 (2015), pp. 929–38.
British Heart Foundation, Takotsubo Cardiomyopathy (1 July 2024)
Saeed Bilal, M.D., University of Toledo Medical Center, Toledo, Ohio (A); and Satoshi Kurisu, M.D., Hiroshima City Hospital, Hiroshima, Japan (B), from Harvard Health Publishing, 'Broken-heart syndrome (takotsubo cardiomyopathy)' (13 June 2023) <https://www.health.harvard.edu/heart-health/takotsubo-cardiomyopathy-broken-heart-syndromeLink opens in a new window> [accessed 2 January 2026]