Waste Water treatment linked to antibiotic resistance
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Validated predictive modelling of the environmental resistome
Gregory CA Amos, Emma Gozzard, Charlotte E Carter, Andrew Mead, Mike J Bowes, Peter M Hawkey, Lihong Zhang, Andrew C Singer, William H Gaze and Elizabeth M H Wellington
Multi-drug-resistant bacteria pose a significant threat to public health. The role of the environment in the overall rise in antibiotic-resistant infections and risk to humans is largely unknown. This study aimed to evaluate drivers of antibiotic-resistance levels across the River Thames catchment, model key biotic, spatial and chemical variables and produce predictive models for future risk assessment.