Job Title
Professor
Department
Life Sciences
Phone
76523184
Web Link
Research Interests
Professor Liz Wellington is an active member of the Environment theme within the School of Life Sciences at the University of Warwick. She holds a personal chair and, with her research group, is involved in the study of bacteria in soil and survival of pathogenic bacteria in the environment. Research work focuses on understanding the ecological roles for specific bacterial activities including antibiotic production, resistance and exoenzyme production and analysing the impact of lateral gene transfer. During the past decade expertise has been developed in the detection, quantification and analysis of soil microbial communities, including the identification of pathogen reservoirs outside of their hosts. Her group was one of the first to report the molecular detection of antibiotic biosynthesis in soil and co-evolution of resistance in non-producers. Subsequent work indicated that waste disposal practices further disseminate antibiotic resistance gene into the environment. Studying the fate of introduced bacteria in the environment has focused on the survival of pathogens such as Salmonella species, MRSA, Dichelobacter nodosus and slow growing mycobacteria including the M. tuberculosis complex. Recent research produced the first non-invasive methods for monitoring shedding in wild life and cattle infected with bTB in order to elucidate the impact of control measures on transmission.
Research Interests:
- Antibiotic resistance dissemination, aim to identify reservoirs of drug resistance in the environment
- Defining environmental reservoirs of pathogenic bacteria in soil and water
- Biodegradation of recalcitrant compounds and biopolymers in the environment
- Microbial community analysis and specific expertise in the development of environmental proteomics for extraction and analysis of enzymes from soils and wastes, and in the processing of biopolymers
- Metagenomics and analyses of microbial gene pools in soil; discovery of novel antibiotic gene clusters
Biography
PhD University of Liverpool 1980
- Waschulin, Valentin, Borsetto, Chiara, James, Robert, Newsham, Kevin K., Donadio, Stefano, Corre, Christophe, Wellington, Elizabeth M. H., 2022. Biosynthetic potential of uncultured Antarctic soil bacteria revealed through long-read metagenomic sequencing. The ISME Journal, 16, pp. 101-111
- Lidbury, Ian, Borsetto, Chiara, Murphy, Andrew, Bottrill, Andrew R., Jones, Alexandra M., Bending, G. D., Hammond, John P., Chen, Yin, Wellington, Elizabeth M. H., Scanlan, David J., 2021. Niche-adaptation in plant-associated Bacteroidetes favours specialisation in organic phosphorus mineralisation. ISME Journal, 15, pp. 1040-1055
- Murphy, Andrew, Scanlan, David J., Chen, Yin, Adams, Nathan B. P., Cadman, William A., Bottrill, Andrew R., Bending, G. D., Hammond, John P., Hitchcock, Andrew, Wellington, Elizabeth M. H., Lidbury, Ian D. E. A., 2021. Transporter characterisation reveals aminoethylphosphonate mineralisation as a key step in the marine phosphorus redox cycle. Nature Communications, 12 (1)
- Hillman, Evette B. M, Rijpkema, Sjoerd, Carson, Danielle, Arasaradnam, Ramesh P., Wellington, Elizabeth M. H., Amos, Gregory C. A., 2021. Manipulating the microbiome : an alternative treatment for bile acid diarrhoea. Microbiology Research, 12 (2), pp. 335-353
- Amos, Gregory C. A., Sergaki, Chrysi, Logan, Alastair, Iriarte, Rolland, Bannaga, Ayman, Chandrapalan, Subashini, Wellington, Elizabeth M. H., Rijpkema, Sjoerd, Arasaradnam, Ramesh P., 2021. Exploring how microbiome signatures change across inflammatory bowel disease conditions and disease locations. Scientific Reports, 11 (1)
- Borsetto, Chiara, Raguideau, Sébastien, Travis, Emma Rachel, Kim, Dae-Wi, Lee, Do-Hoon, Bottrill, Andrew R., Stark, Richard Jan, Song, Lijiang, Cha, Chang-Jun, Pearson, Jonathan M., Quince, Christopher, Singer, Andrew C., Wellington, Elizabeth M. H., 2021. Impact of sulfamethoxazole on a riverine microbiome. Water Research, 201
- Rangama, Severine, Lidbury, Ian, Holden, Jennifer, Borsetto, Chiara, Murphy, Andrew, Hawkey, Peter, Wellington, E. M. H., Rangama, Severine, Lidbury, Ian, Holden, Jennifer, Borsetto, Chiara, Murphy, Andrew, Hawkey, Peter, Wellington, E. M. H., 2021. Mechanisms involved in the active secretion of CTX-M-15 ß-lactamase by pathogenic Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 65 (10)
- Lee, Kihyun, Kim, Dae-Wi, Lee, Do-Hoon, Kim, Yong-Seok, Bu, Ji-Hye, Cha, Ju-Hee, Thawng, Cung Nawl, Hwang, Eun-Mi, Seong, Hoon Je, Sul, Woo Jun, Wellington, Elizabeth M. H., Quince, Christopher, Cha, Chang-Jun, 2020. Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance. Microbiome, 8 (1)
- Alam, Mohammad T., Amos, Gregory C. A., Murphy, Andrew, Murch, Simon, Wellington, E. M. H., Arasaradnam, Ramesh P., 2020. Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels. Gut Pathogens, 12
- Styles, Kathryn, Thummeepak, Rapee, Leungtongkam, Udomluk, Smith, Sophie, Christie, Gabrielle S., Millard, Andrew D., Moat, John, Dowson, Christopher G., Wellington, Elizabeth M. H., Sitthisak, Sutthirat, Sagona, Antonia P., 2020. Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii. Antibiotics, 9 (4)
- Murphy, Andrew, Travis, Emma Rachel, Hibberd, Victoria, Porter, David, Wellington, Elizabeth M. H., 2020. Evaluation of a fecal shedding test to detect badger social groups infected with Mycobacterium bovis. Journal of Clinical Microbiology, 59 (1)
- Leungtongkam, Udomluk, Thummeepak, Rapee, Kitti, Thawatchai, Tasanapak, Kannipa, Wongwigkarn, Jintana, Styles, Kathryn, Wellington, Elizabeth M. H., Millard, Andrew D., Sagona, Antonia P., Sitthisak, Sutthirat, 2020. Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii. Scientific Reports, 10
- Kim, Dae-Wi, Thawng, Cung Nawl, Lee, Kihyun, Wellington, E. M. H., Cha, Chang-Jun, 2019. A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria. Environment International, 127, pp. 206-215
- Borsetto, Chiara, Amos, Gregory C. A., da Rocha, Ulisses Nunes, Mitchell, Alex L., Finn, Robert D., Laidi, Rabah Forar, Vallin, Carlos, Pearce, David A., Newsham, Kevin K., Wellington, E. M. H., 2019. Microbial community drivers of PK/NRP gene diversity in selected global soils. Microbiome, 7 (1)
- Simcox, Lee J., Pereira, Rui P. A., Wellington, E. M. H., Macpherson, Julie V., 2019. Boron doped diamond as a low biofouling material in aquatic environments : assessment of pseudomonas aeruginosa biofilm formation. ACS Applied Materials and Interfaces, 11
- Zhang, Lihong, Calvo-Bado, Leo A., Murray, A. K., Amos, Gregory C. A., Hawkey, P. M., Wellington, E. M. H., Gaze, William H., 2019. Novel clinically relevant antibiotic resistance genes associated with sewage sludge and industrial waste streams revealed by functional metagenomic screening. Environment International, 132
- Amin, Dina, Abolmaaty, Assem, Tolba, Sahar, Abdallah, Nagwa, Wellington, E. M. H., 2018. Phylogenic characteristics of a unique antagonistic micromonospora Sp. Rc5 to S. aureus isolated from Sinai Desert of Egypt. Annual Research & Review in Biology, 22 (2), pp. 1-15
- Amos, Gregory C. A., Ploumakis, Semina, Zhang, Lihong, Hawkey, Peter M., Gaze, William H., Wellington, E. M. H., 2018. The widespread dissemination of integrons throughout bacterial communities in a riverine system. The ISME Journal, 12 (3), pp. 681-691
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Larsson, D.G. Joakim, Andremont, Antoine, Bengtsson-Palme, Johan, Brandt, Kristian Koefoed, de Roda Husman, Ana Maria, Fagerstedt, Patriq, Fick, Jerker, Flach, Carl-Fredrik, Gaze, William H., Kuroda, Makoto, Kvint, Kristian, Laxminarayan, Ramanan, Manaia, Celia M., Nielsen, Kaare Magne, Plant, Laura, Ploy, Marie-Cécile, Segovia, Carlos, Simonet, Pascal, Smalla, Kornelia, Snape, Jason et al (Select to open full list), 2018. Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance. Environment International, 117, pp. 132-138
- Lidbury, Ian, Murphy, Andrew, Fraser, Tandra D., Bending, G. D., Jones, Alexandra M., Moore, Jonathan D., Goodall, Andrew, Tibbetts, Mark, Hammond, John P., Scanlan, David J., Wellington, E. M. H., 2017. Identification of extracellular glycerophosphodiesterases in Pseudomonas and their role in soil organic phosphorus remineralisation. Scientific Reports, 7 (1)
- Lidbury, Ian, Fraser, Tandra, Murphy, Andrew, Scanlan, David J., Bending, G. D. (Gary D.), Jones, Alexandra M., Moore, Jonathan D., Goodall, Andrew, Tibbett, Mark, Hammond, John P., Wellington, E. M. H., 2017. The ?known' genetic potential for microbial communities to degrade organic phosphorus is reduced in low-pH soils.. MicrobiologyOpen
- Kaur, Amandeep, Hernandez Fernaud, Juan Ramon, Aguilo-Ferretjans, Maria del Mar, Wellington, E. M. H., Christie-Oleza, Joseph Alexander, 2017. 100 days of marine Synechococcus ? Ruegeria pomeroyi interaction, a detailed analysis of the exoproteome. Environmental Microbiology, 20 (2), pp. 785-799
- Konstantopoulou, Marina, Slator, Paddy J., Taylor, Charles R., Wellington, E. M. H., Allison, Gordon, Harper, Andrea L., Bancroft, Ian, Bugg, Timothy D. H., 2017. Variation in susceptibility to microbial lignin oxidation in a set of wheat straw cultivars : influence of genetic, seasonal and environmental factors. Nordic Pulp and Paper Research Journal, 32 (4), pp. 493-507
- King, Hayley C., Khera-Butler , Tanya, James, Phillip, Oakley, Brian B., Erenso, Girume, Aseffa, Abraham, Knight, Robert, Wellington, E. M. H., Courtenay, Orin, 2017. Environmental reservoirs of pathogenic mycobacteria across the Ethiopian biogeographical landscape. PLoS One, 12 (3)
- Cruz, João C. S., Maffioli, Sonia I., Bernasconi, Alice, Brunati, Cristina, Gaspari, Eleonora, Sosio, Margherita, Wellington, E. M. H., Donadio, Stefano, 2016. Allocyclinones, hyperchlorinated angucyclinones from Actinoallomurus. The Journal of Antibiotics
- Lidbury, Ian, Murphy, Andrew, Scanlan, David J., Bending, G. D., Jones, Alexandra M., Moore, Jonathan D., Goodall, Amanda, Hammond, John P., Wellington, E. M. H., 2016. Comparative genomic, proteomic and exoproteomic analyses of three Pseudomonas strains reveals novel insights into the phosphorus scavenging capabilities of soil bacteria. Environmental Microbiology, 18 (10), pp. 3535-3549
- Cleary, David W., Bishop, Alistair H., Zhang, Lihong, Topp, Edward, Wellington, E. M. H., Gaze, William H., Smalla, Kornelia, 2016. Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. FEMS Microbiology Ecology, 92 (10)
- Gudeta, Dereje Dadi, Bortolaia, Valeria, Amos, Gregory C. A., Wellington, E. M. H., Brandt, Kristian K., Poirel, Laurent, Nielsen, Jesper Boye, Westh, Henrik, Guardabassi, Luca, 2016. The soil microbiota harbors a diversity of Carbapenem-Hydrolyzing ß-Lactamases of potential clinical relevance. Antimicrobial Agents and Chemotherapy, 60 (1), pp. 151-160
- Salimraj, Ramya, Zhang, Lihong, Hinchliffe, Philip, Wellington, E. M. H., Brem, Jürgen, Schofield, Christopher J., Gaze, William H., Spencer, James, 2016. Structural and biochemical characterization of Rm3, a subclass B3 Metallo-ß-Lactamase identified from a functional metagenomic study. Antimicrobial Agents and Chemotherapy, 60 (10), pp. 5828-5840
- Lehmann, Katja, Bell, Thomas, Bowes, Michael J., Amos, Gregory C. A., Gaze, William H., Wellington, E. M. H., Singer, Andrew C., 2016. Trace levels of sewage effluent are sufficient to increase class 1 integron prevalence in freshwater biofilms without changing the core community. Water Research, 106, pp. 163-170
- Cruz, João C. S., Iorio, Marianna, Monciardini, Paolo, Simone, Matteo, Brunati, Cristina, Gaspari, Eleonora, Maffioli, Sonia I., Wellington, E. M. H., Sosio, Margherita, Donadio, Stefano, 2015. Brominated variant of the Lantibiotic NAI-107 with enhanced antibacterial potency. Journal of Natural Products, 78 (11), pp. 2642-2647
- Christie-Oleza, Joseph Alexander, Sousoni, Despoina, Armengaud, Jean, Wellington, E. M. H., Jones, Alexandra M., 2015. Defining a pipeline for metaproteomic analyses. Springer Protocols Handbooks
- Amos, Gregory C. A., Borsetto, Chiara, Laskaris, Paris, Krsek, Martin, Berry, Andrew E., Newsham, Kevin K., Calvo-Bado, Leo A., Pearce, David A., Vallin, Carlos, Wellington, E. M. H., 2015. Designing and implementing an assay for the detection of rare and divergent NRPS and PKS clones in European, Antarctic and Cuban soils. PLoS One, 10 (9), pp. 1-15
- Müller, Christina A., Oberauner-Wappis, Lisa, Peyman, Armin, Amos, Gregory C. A., Wellington, E. M. H., Berg, Gabriele, 2015. Mining for nonribosomal peptide synthetase and polyketide synthase genes revealed a high level of diversity in the sphagnum bog metagenome. Applied and Environmental Microbiology, 81 (15), pp. 5064-5072
- Muzafar, Mohd, Green, Laura E., Calvo-Bado, Leo A., Tichauer, Esther, King, Hayley C., James, Philip, Wellington, E. M. H., 2015. Survival of the ovine footrot pathogen Dichelobacter nodosus in different soils. Anaerobe, 38, pp. 81-87
- Muzafar, Mohd, Calvo-Bado, Leo A., Green, Laura E., Smith, Edward M., Russell, Claire L., Grogono-Thomas, Rosemary, Wellington, E. M. H., 2015. The role of the environment in transmission of Dichelobacter nodosus between ewes and their lambs. Veterinary Microbiology, 179 (1-2), pp. 53-59
- King, Hayley C., Murphy, Andrew, James, Phillip, Travis, Emma Rachel, Porter, David, Hung, Yu-Jiun, Sawyer, Jason, Cork, Jennifer, Delahay, Richard J., Gaze, William H., Courtenay, Orin, Wellington, E. M. H., 2015. The variability and seasonality of the environmental reservoir of Mycobacterium bovis shed by wild European badgers. Scientific Reports, 5, pp. 1-7
- Amos, Gregory C. A., Gozzard, Emma, Carter, Charlotte E., Mead, A. (Andrew), Bowes, Mike J., Hawkey, P. M., Zhang, Lihong, Singer, Andrew C., Gaze, William H., Wellington, E. M. H., 2015. Validated predictive modelling of the environmental resistome. The ISME Journal, 9
- King, Hayley C., Murphy, Andrew, James, Phillip, Travis, Emma Rachel, Porter, David, Sawyer, Jason, Cork, Jennifer, Delahay, Richard J., Gaze, William H., Courtenay, Orin, Wellington, E. M. H., 2015. Performance of a non-invasive test for detecting mycobacterium bovis shedding in European badger (meles meles) populations. Journal of Clinical Microbiology, 53, pp. 2316-2323
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Roca, Ignasi, Akova, Murat, Baquero, F., Carlet, Jean, Cavaleri, Marco, Coenen, Samuel, Cohen, J., Findlay, D., Gyssens, Inge, Heure, O. E., Kahlmeter, Gunnar, Kruse, H., Laxminarayan, Ramanan, Liébana, Ernesto, López-Cerero, Lorena, MacGowan, Alasdair, Martins, Marta, Rodríguez-Baño, Jesus, Rolain, Jean-Marc, Segovia, Carlos et al (Select to open full list), 2015. The global threat of antimicrobial resistance : science for intervention. New Microbes and New Infections, 6, pp. 22-29
- Witcomb, Luci, Green, Laura E., Calvo-Bado, Leo A., Russell, Claire, Smith, Edward M., Grogono-Thomas, Rose, Wellington, E. M. H., 2015. First study of pathogen load and localisation of ovine footrot using fluorescence in situ hybridisation (FISH). Veterinary Microbiology, 176 (3?4), pp. 321-327
- Wellington, E. M. H., Courtenay, Orin, 2014. Comment : Badgers and Bovine TB ? how can environmental microbiology help?. Microbiology Today, 41 (3)
- Dealtry, Simone, Ding, Guo-Chun, Weichelt, Viola, Dunon, Vincent, Schlüter, Andreas, Martini, María Carla, Papa, María Florencia Del, Lagares, Antonio, Amos, Gregory C. A., Wellington, E. M. H., Gaze, William H., Sipkema, Detmer, Sjöling, Sara, Springael, Dirk, Heuer, Holger, Elsas, J. D. van, Thomas, Christopher M., Smalla, Kornelia, 2014. Cultivation-independent screening revealed hot spots of IncP-1, IncP-7 and IncP-9 plasmid occurrence in different environmental habitats. PLoS One, 9 (2)
- Amos, Gregory C. A., Zhang, Lihong, Hawkey, P. M., Gaze, William H., Wellington, E. M. H., 2014. Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes. Veterinary Microbiology, 171 (3-4), pp. 441-447
- Mohamad, A. J., Zhu, Xinyao, Tian, Y. (Yuan), Wellington, E. M. H., Pfleging, W., Liu, X., 2014. Investigating the effect of surface topography on hydrophobicity and bacterial attachment on polystyrene. Surface Topography : Metrology and Properties, 2 (2)
- Selama, Okba, Amos, Gregory C. A., Djenane, Zahia, Borsetto, Chiara, Laidi, Rabah Forar, Porter, David, Nateche, Farida, Wellington, E. M. H., Hacène, Hocine, 2014. Screening for genes coding for putative antitumor compounds, antimicrobial and enzymatic activities from haloalkalitolerant and haloalkaliphilic bacteria strains of Algerian Sahara soils. BioMed Research International, 2014
- Amos, Gregory C. A., Hawkey, P. M., Gaze, William H., Wellington, E. M. H., 2014. Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment. Journal of Antimicrobial Chemotherapy, 69 (7), pp. 1785-1791
- Johnson-Rollings, Ashley S., Wright, H., Masciandaro, Grazia, Macci, Cristina, Doni, Serena, Calvo-Bado, Leo A., Slade, Susan E., Plou, Carlos Vallin, Wellington, E. M. H., 2014. Exploring the functional soil-microbe interface and exoenzymes through soil metaexoproteomics. The ISME Journal, 8 (10), pp. 2148-2150
- Smith, Edward M., Green, Olivia, Calvo-Bado, Leo A., Witcomb, Luci, Grogono-Thomas, Rosemary, Russell, Claire L., Brown, J. C., Medley, Graham, Kilbride, A. L., Wellington, E. M. H., Green, Laura E., 2014. Dynamics and impact of footrot and climate on hoof horn length in 50 ewes from one farm over a period of 10 months. The Veterinary Journal, 201 (3), pp. 295-301
- Witcomb, Luci, Green, Laura E., Kaler, Jasmeet, Ul-Hassan, Atiya, Calvo-Bado, Leo A., Medley, Graham, Grogono-Thomas, Rosemary, Wellington, E. M. H., 2014. A longitudinal study of the role of Dichelobacter nodosus and Fusobacterium necrophorum load in initiation and severity of footrot in sheep. Preventive Veterinary Medicine, 115 (1-2), pp. 48-55
- Russell, Claire L., Smith, Edward M., Calvo-Bado, Leo A., Green, Laura E., Wellington, E. M. H., Medley, Graham, Moore, Lynda J., Grogono-Thomas, Rosemary, 2014. Multiple locus VNTR analysis highlights that geographical clustering and distribution of Dichelobacter nodosus, the causal agent of footrot in sheep, correlates with inter-country movements. Infection, Genetics and Evolution, 22 (1), pp. 273-279
- Gaze, William H., Krone, Stephen M., Larsson, D.G. Joakim, Li, Xian-Zhi, Robinson, Joseph A., Simonet, Pascal, Smalla, Kornelia, Timinouni, Mohammed, Topp, Ed, Wellington, E. M. H., Wright, Gerard D., Zhu, Yong-Guan, 2013. Influence of humans on evolution and mobilization of environmental antibiotic resistome. Emerging Infectious Diseases, 19 (7)
- Wellington, E. M. H., Boxall, Alistair B. A., Cross, Paul, Feil, Edward J., Gaze, William H., Hawkey, P. M., Johnson-Rollings, Ashley S., Jones, Davey L., Lee, Nick, Otten, Wilfred, Thomas, Christopher M., Williams, A. Prysor, 2013. The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria. The Lancet Infectious Diseases, Vol.13 (No.2), pp. 155-165
- Pontiroli, Alessandra, Khera, Tanya T., Oakley, Brian B., Mason, Sam, Dowd, Scot E., Travis, Emma Rachel, Erenso, Girum, Aseffa, Abraham, Courtenay, Orin, Wellington, E. M. H., 2013. Prospecting environmental mycobacteria: combined molecular approaches reveal unprecedented diversity. PLoS One, 8 (7)
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Engel, Katja, Ashby, Deborah, Brady, Sean F., Cowan, Don A., Doemer, John, Edwards, E. A., Fiebig, Klaus, Martens, Eric C., McCormac, Dennis, Mead, David A., Miyazaki, Kentaro, Moreno-Hagelsieb, Gabriel, O'Gara, F., Reid, A., Rose, David R., Simonet, Pascal, Sjöling, Sara, Smalla, K., Streit, Wolfgang R., Tedman-Jones, Jennifer et al (Select to open full list), 2013. Meeting report : 1st international functional metagenomics workshop May 7?8, 2012, St. Jacobs, Ontario, Canada. Standards in Genomic Sciences, 8 (1), pp. 106-111
- Thomas, L., Hodgson, D. A., Wentzel, A., Nieselt, K., Ellingsen, T. E., Moore, Jonathan D., Morrissey, Edward R., Legaie, Roxane, Wohlleben, W., Rodriguez-Garcia, A., Martin, J. F., Burroughs, Nigel John, Wellington, E. M. H., Smith, M. C. M., 2012. Metabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture. Molecular & Cellular Proteomics, Vol.11 (No.2)
- Edwards, Lindsey A., O'Neill, Colette, Furman, Mark A., Hicks, Susan, Torrente, Franco, Pérez-Machado, Miguel, Wellington, E. M. H., Phillips, Alan D., Murch, Simon, 2012. Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation. Inflammatory Bowel Diseases, Vol.18 (No.4), pp. 624-640
- Laskaris, Paris, Sekine, Takuya, Wellington, E. M. H., 2012. Diversity analysis of Streptomycetes and associated phosphotranspherase genes in soil. PLoS ONE, Vol.7 (No.4)
- Martín, Juan F., Santos-Beneit, Fernando, Rodríguez-García, Antonio, Sola-Landa, Alberto, Smith, Margaret C. M., Ellingsen, Trond E., Nieselt, Kay, Burroughs, Nigel John, Wellington, E. M. H., 2012. Transcriptomic studies of phosphate control of primary and secondary metabolism in Streptomyces coelicolor. Applied Microbiology and Biotechnology, Vol.95 (No.1), pp. 61-75
- Pearce, David A., Newsham, Kevin K., Thorne, Michael A. S., Calvo-Bado, Leo A., Krsek, Martin, Laskaris, Paris, Hodson, Andrew J., Wellington, E. M. H., 2012. Metagenomic analysis of a southern maritime Antarctic soil. Frontiers in Microbiology, 3
- Travis, Emma Rachel, Gaze, William H., Pontiroli, Alessandra, Sweeney, Francis P., Porter, David, Mason, Sam, Keeling, Matthew James, Jones, Rebecca M., Sawyer, Jason, Aranaz, Alicia, Castellanos Rizaldos, Elena, Cork, Jennifer, Delahay, Richard J., Wilson, Gavin J., Hewinson, R. Glyn, Courtenay, Orin, Wellington, E. M. H., 2011. An inter-laboratory validation of a real time PCR assay to measure host excretion of bacterial pathogens, particularly of mycobacterium bovis. PLoS One, Vol.6 (No.11)
- Gaze, William H., Zhang, Lihong, Abdouslam, Nouradin A., Hawkey, P. M., Calvo-Bado, Leo A., Royle, Jeremy, Brown, Helen, Davis, Susan, Kay, Paul, Boxall, Alistair B. A., Wellington, E. M. H., 2011. Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment. ISME Journal, Vol.5 (No.8), pp. 1253-1261
- Anukool, Usanee, O'Neill, Colette E., Butr-Indr, Bordin, Hawkey, P. M., Gaze, William H., Wellington, E. M. H., 2011. Meticillin-resistant Staphylococcus aureus in pigs from Thailand. International Journal of Antimicrobial Agents, 38 (1), pp. 86-87
- Gaze, William H., Morgan, Gina, Zhang, Lihong, Wellington, E. M. H., 2011. Mimivirus-like particles in Acanthamoebae from sewage sludge. Emerging Infectious Diseases, 17 (6), pp. 1127-1129
- Calvo-Bado, Leo A., Oakley, Brian B., Dowd, Scot E., Green, Laura E., Medley, Graham, Ul-Hassan, Atiya, Bateman, Vicky, Gaze, William H., Witcomb, Luci, Grogono-Thomas, Rosemary, Kaler, Jasmeet, Russell, Claire L., Wellington, E. M. H., 2011. Ovine pedomics : the first study of the ovine foot 16S rRNA-based microbiome. ISME Journal, Vol.5 (No.9), pp. 1426-1437
- Pontiroli, Alessandra, Travis, Emma Rachel, Sweeney, F. P., Porter, David, Gaze, William H., Mason, Sam, Hibberd, V., Holden, Jennifer, Courtenay, Orin, Wellington, E. M. H., 2011. Pathogen quantitation in complex matrices : a multi-operator comparison of DNA extraction methods with a novel assessment of PCR inhibition. PLoS One, Vol.6 (No.3)
- Tsibidis, George D., Burroughs, Nigel John, Gaze, William H., Wellington, E. M. H., 2011. Semi-automated Acanthamoeba polyphaga detection and computation of Salmonella typhimurium concentration in spatio-temporal images. Micron, Vol.42 (No.8), pp. 911-920
- Byrne-Bailey, K. G., Gaze, William H., Zhang, Lihong, Kay, Paul, Boxall, Alistair B.A., Hawkey, P. M., Wellington, E. M. H., 2011. Integron prevalence and diversity in manured soil. Applied and Environmental Microbiology, Vol.77 (No.2), pp. 684-687
- Reddy, T. V. K., Mahmood, Shaik, Laskaris, Paris, Reddy, Y. Harish Kumar, Wellington, E. M. H., Idris, M. M., 2011. Streptomyces hyderabadensis sp. nov., an actinomycete isolated from soil. International Journal of Systematic and Evolutionary Microbiology, 61 (1), pp. 76-80
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Nieselt, Kay, Battke, Florian, Herbig, Alexander, Bruheim, Per, Wentzel, Alexander, Jakobsen, Øyvind M, Sletta, Håvard, Alam, Mohammad Tauqee, Merlo, Maria E., Moore, Jonathan, Omara, Walid A. M., Morrissey, Edward R., Juarez-Hermosillo, Miguel A, Rodríguez-García, Antonio, Nentwich, Merle, Thomas, Louise, Iqbal, Mudassar, Legaie, Roxane, Gaze, William H., Challis, Gregory L. et al (Select to open full list), 2010. The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics, 11
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Nieselt, Kay, Battke, Florian, Herbig, Alexander, Bruheim, Per, Wentzel, Alexander, Jakobsen, Øyvind M., Sletta, Håvard, Alam, Mohammad T., Merlo, Maria E., Moore, Jonathan D., Omara, Walid A. M., Morrissey, Edward R., Juárez, Miguel A., Rodríguez-García, Antonio, Nentwich, Merle, Thomas, L., Iqbal, Mudassar, Legaie, Roxane, Gaze, William H., Challis, Gregory L. et al (Select to open full list), 2010. The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics, Vol.11 (Article 10)
- Calvo-Bado, Leo A., Green, Laura E., Medley, Graham, Ul-Hassan, Atiya, Buller, Nicky B., Kaler, Jasmeet, Russell, Claire L., Kennan, Ruth M., Rood, Julian I., Wellington, E. M. H., Grogono-Thomas, Rosemary, 2010. Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus. Veterinary Microbiology, Vol.147 (No.3-4), pp. 358-366
- Alam, Mohammad T., Merlo, Maria E., Hodgson, D. A., Wellington, E. M. H., Takano, Eriko, Breitling, Rainer, 2010. Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor. BMC Genomics, Vol.11 (No.202)
- Kaler, Jasmeet, Medley, Graham, Grogono-Thomas, Rosemary, Wellington, E. M. H., Calvo-Bado, Leo A., Wassink, Geert J., King, Elisabeth M., Moore, L. J., Russell, Claire L., Green, Laura E., 2010. Factors associated with changes of state of foot conformation and lameness in a flock of sheep. Preventive Veterinary Medicine, Vol.97 (No.3/4), pp. 237-244
- Laskaris, Paris, Tolba, Sahar, Calvo-Bado, Leo A., Wellington, E. M. H., 2010. Coevolution of antibiotic production and counter-resistance in soil bacteria. Environmental Microbiology, Vol.12 (No.3), pp. 783-796
- Boxall, Alistair B.A., Hardy, Anthony, Beulke, Sabine, Boucard, Tatiana, Burgin, Laura, Falloon, Peter D., Haygarth, Philip M., Hutchinson, Thomas, Kovats, R. Sari, Leonardi, Giovanni, Levy, Leonard S., Nichols, Gordon, Parsons, Simon, Potts, Laura, Stone, David, Topp, Edward, Turley, David B., Walsh, Kerry, Wellington, E. M. H., Williams, Richard J., 2009. Impacts of Climate Change on indirect human exposure to pathogens and chemicals from agriculture. Environmental Health Perspectives, Vol.11 (No.4), pp. 508-514
- Byrne-Bailey, K. G., Gaze, William H., Kay, Paul, Boxall, Alistair B.A., Hawkey, P. M., Wellington, E. M. H., 2009. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. Antimicrobial Agents and Chemotherapy, Vol.53 (No.2), pp. 696-702
- Gaze, William H., O'Neill, Colette, Wellington, E. M. H., Hawkey, P. M., 2008. Antibiotic resistance in the environment, with particular reference to MRSA. Advances in Applied Microbiology, Vol.63, pp. 249-280
- Courtenay, Orin, Wellington, E. M. H., 2008. Mycobacterium bovis in the environment : towards our understanding of its biology. Cattle Practice, Vol.16 (Part 2), pp. 122-126
- Masciandaro, Grazia, Macci, Cristina, Doni, Serena, Maserti, Bianca Elena, Leo, A. Calvo-Bado, Ceccanti, Brunello, Wellington, E. M. H., 2008. Comparison of extraction methods for recovery of extracellular beta-glucosidase in two different forest soils. Soil Biology & Biochemistry, Vol.40 (No.9), pp. 2156-2161
- Sweeney, F. P., Courtenay, Orin, Hibberd, V., Hewinson, R. G., Reilly, L. A., Gaze, William H., Wellington, E. M. H., 2007. Environmental monitoring of Mycobacterium bovis in badger feces and badger sett soil by real-time PCR, as confirmed by immunofluorescence, immunocapture, and cultivation. Applied and Environmental Microbiology, Vol.73 (No.22), pp. 7471-7473
- Courtenay, Orin, Reilly, L. A., Keeling, Matthew James, Sweeney, F. P., Wellington, E. M. H., Macdonald, David W., Delahay, Richard J., Wilson, G. J., Cheeseman, C. L., 2007. Performance of an environmental test to detect Mycobacterium bovis infection in badger social groups. Veterinary Record, The, Vol.161, pp. 817-818
- Krsek, Martin, Wellington, E. M. H., 2006. Studies of microbial community structure and function below ground in a managed upland grassland site at Sourhope Research Station. Applied Soil Ecology, 33 (2), pp. 127-136
- Courtenay, Orin, Reilly, L. A., Sweeney, F. P., Hibberd, V., Bryan, S., Ul-Hassan, Atiya, Newman, C., Macdonald, D. W., Delahay, R. J., Wilson, G. J., Wellington, E. M. H., 2006. Is Mycobacterium bovis in the environment important for the persistence of bovine tuberculosis?. Biology Letters, Vol.2 (No.3), pp. 460-462
- Sweeney, F. P., Courtenay, Orin, Ul-Hassan, Atiya, Hibberd, V., Reilly, L. A., Wellington, E. M. H., 2006. Immunomagnetic recovery of Mycobacterium bovis from naturally infected environmental samples. LETTERS IN APPLIED MICROBIOLOGY, 43 (4), pp. 364-369
- Ul-Hassan, Atiya, Wellington, E. M. H., 2009. Actinobacteria. In Encyclopedia of Microbiology, Elsevier, pp. 25-44
- Rossello, M. R., Griffiths, Nathan, Kalvala, Sara, Wellington, E. M. H., Gaze, William H., 2009. Networking strategies in streptomyces coelicolor. 2nd International Conference on Bioinformatics and Systems Biology (BSB 2009), Leipzig, Germany, 23-25 March 2009
- Edwards, L., Hicks, S., Furman, M., O'Neill, C., Wellington, E. M. H., Torrente, F., Fitzhenry, R., Phillips, A., Murch, Simon, 2007. Seg/I producing Staphylococcus aureus induces intestinal epithelial cytopathy independent of T cell responses. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Barcelona, Spain, May 9-12, 2007, Published in Journal of Pediatric Gastroenterology and Nutrition, pp. 118-118
- Lee, Learn-Han, Chan, Kok-Gan, Stach, Jem, Wellington, Elizabeth M. H., Goh, Bey-Hing, 2018. Editorial: The Search for Biological Active Agent(s) From Actinobacteria. Frontiers in Microbiology, Frontiers Research Foundation
- Amos, Gregory C. A., Carter, Abigail, Hawkey, Peter M., Gaze, William H., Wellington, E. M. H., 2015. The hidden resistome of retail chicken meat. Journal of Global Antimicrobial Resistance, Elsevier BV, pp. 44-46
- Roug, Annette, Geoghegan, Claire, Wellington, E. M. H., Miller, Woutrina A., Travis, Emma Rachel, Porter, David, Cooper, David, Clifford, Deana L., Mazet, Jonna A. K., Parsons, Sven, 2014. Utility of a fecal real-time PCR protocol for detection of Mycobacterium bovisInfection in African buffalo (syncerus caffer). Journal of Wildlife Diseases, Wildlife Disease Association, Inc, pp. 140-142
- Laskaris, Paris, Tolba, Sahar, Calvo-Bado, Leo A., Wellington, E. M. H., 2010. Corrigendum to "Coevolution of antibiotic production and counter-resistance in soil bacteria". Environmental Microbiology, Blackwell, pp. 2048-2048
- Boxall, Alistair, Hardy, Anthony, Beulke, Sabine, Boucard, Tatiana, Burgin, Laura, Falloon, Peter, Haygarth, Philip, Hutchinson, Thomas, Kovats, Sari, Leonardi, Giovanni, Levy, Leonard, Nichols, Gordon, Parsons, Simon, Potts, Laura, Stone, David, Topp, Edward, Turley, David, Walsh, Kerry, Wellington, E. M. H., Williams, Richard, 2010. Impacts of climate change on indirect human exposure to pathogens and chemicals from agriculture. Ciencia & Saude Coletiva, Abrasco, pp. 743-756
- Boxall, Alistair B. A., Hardy, Anthony, Beulke, Sabine, Boucard, Tatiana, Burgin, Laura, Falloon, Peter D., Haygarth, Philip M., Hutchinson, Thomas, Kovats, R. Sari, Leonardi, Giovanni, Levy, Leonard S., Nichols, Gordon, Parsons, Simon A., Potts, Laura, Stone, David, Topp, Edward, Turley, David B., Walsh, Kerry, Wellington, E. M. H., Williams, Richard J., 2009. Impacts of climate change on indirect human exposure to pathogens and chemicals from agriculture. Environmental Health Perspectives, US Department of Health and Human Services, pp. 508-514
| Title | Funder | Award start | Award end |
|---|---|---|---|
| MTA - DSMZ - tba (Lobna HUDIFA, PI: Liz Wellington) | Leibniz-Institut DSMZ | 05 Nov 2020 | 04 Nov 2025 |
| HPRU in Genomics and Enabling at University of Warwick | National Institute for Health Research (DoH) | 01 Apr 2020 | 31 Mar 2025 |
| Resolving the fate and studying the impact of pharmaceutical wastes on the environment and local community of a pharmaceutical manufacturing hub | NERC | 01 Oct 2020 | 30 Sep 2023 |
| CENTA Doctoral Training Partnership (led by Birmingham) | NERC | 01 Oct 2014 | 30 Sep 2023 |
| India-UK Tackling AMR in the Environment from Antimicrobial Manufacturing Waste (AMR India) Programme Coordination Team | NERC | 01 Sep 2021 | 28 Feb 2023 |
| Microbial hitch-hikers of marine plastics: the survival, persistence & ecology of microbial communities in the 'Plastisphere' | NERC | 14 Jan 2019 | 13 Jan 2023 |
| Studentship Agreement with NIBSC for Evette Hillman | National Institute of Biological Standards and Control (NIBSC) | 30 Sep 2019 | 29 Sep 2022 |
| HT MTA with Arden Tissue Bank to recieve blood samples | University Hospitals Coventry and Warwickshire NHS Trust | 14 Mar 2019 | 13 Mar 2022 |
| Combatting Antimicrobial Resistance Training Network | European Commission | 01 Jan 2018 | 31 Dec 2021 |
| LinkPI: Linking Phenotype function with Identity: a novel integrated single-cell technology and metagenomics approach - Nerc Global Partnership seedcorn fund | NERC | 01 Nov 2018 | 31 Aug 2021 |
| Ion mobility mass spectrometer for proteomics facility. ALERT19 | BBSRC | 01 Jul 2020 | 30 Jun 2021 |
| Strain resolved metagenomics for medical microbiology | MRC | 01 Oct 2019 | 15 Apr 2021 |
| FAPIC - Fast Assay for Pathogen Identification and Characterisation (v2) | European Commission | 01 Jun 2015 | 31 Oct 2020 |
| UK Thailand - Overcoming the opportunistic pathogen Acinetobacter baumannii in Thailand? developing bacteriophages as antimicrobial agents | British Council | 01 Apr 2018 | 31 Mar 2020 |
| The farm environment: an overlooked reservoir of Mycobacterium bovis? | BBSRC | 01 Apr 2016 | 31 Mar 2020 |
| New approaches to resolving community metaproteomes: ComProt | NERC | 01 Jan 2019 | 31 Dec 2019 |
| Chicken or the Egg: Is AMR in the Environment Driven by Dissemination of Antibiotics or Antibiotic Resistance Genes? | NERC | 01 May 2016 | 31 Dec 2019 |
| Phosphorus cycling in the soil-microbe-plant continuum of agri-ecosystems | BBSRC | 31 Dec 2014 | 31 Jul 2019 |
| MRC-KHIDI UK-KOREA PARTNERING AWARDS -Exploring the relationship between antibiotic persistence and antibiotic resistance in exposed bacteria in environmental locations | MRC | 31 May 2018 | 30 Apr 2019 |
| Programme Integration Group (PIG) - Using next generation sequencing to reveal human impact on aquatic reservoirs of antibiotic resistant bacteria at the catchment scale | NERC | 01 Jul 2017 | 31 Dec 2018 |
| Using next generation sequencing to reveal human impact on aquatic reservoirs of antibiotic resistant bacteria at the catchment scale | NERC | 04 May 2015 | 31 Dec 2018 |
| MRC AMR Development Grant application - AMREPAK: Novel inter-disciplinary approaches for identifying and tackling the spread of AntiMicrobial Resistance through Environmental pathways in PAKistan | MRC | 01 Oct 2017 | 31 Mar 2018 |
| Diversity of chlamydia and other bacterial species within amoebae isolated from river sediments - Harry Smith Vacation Studentship Chandara Olgunsoy | Microbiology Society | 11 Jul 2016 | 10 Jul 2017 |
| Community Network in metagenomics: The exploitation of metagenomics and meta-omics approaches in life science research | BBSRC | 01 Feb 2014 | 31 May 2017 |
| PhD scholarship for Jenny Johnson under the British Council Newton-Mosharafa Fund Title: Metagenomic analysis in gauging the innate microbial community structure and metabolic potential of a contaminated site - A study towards bioremediation | British Council | 01 Apr 2016 | 31 Mar 2017 |
| Exploiting microbial genomics and synthetic biology for discovery of novel antibiotics | BBSRC | 01 Sep 2013 | 30 Sep 2016 |
| TRAIN-ASAP 2011 | European Commission | 01 Jan 2012 | 19 Sep 2016 |
| KTP Partnership with Biome Technologies PLC | Technology Strategy Board | 01 Jul 2013 | 30 Jun 2016 |
| KTP Partnership with Biome Technologies PLC - Life Science Component of 36502 | Technology Strategy Board | 01 Jul 2013 | 30 Jun 2016 |
| Agreement for the joint funding of a drug development programme | NERC | 01 Apr 2013 | 31 Mar 2016 |
| Detection of Mycobacterium bovis in badger faeces: an inter-laboratory comparison study | Department for Environment, Food and Rural Affairs | 17 Oct 2014 | 16 Oct 2015 |
| Exploitation of novel metabolites from Antarctic metagenomes (MyIP383) - NERC Innovation Fund (Application for part A Funding ) | NERC | 01 Jul 2014 | 31 Aug 2015 |
| Tuberculosis epidemiology and novel transmission routes in rural Tanzania (NIH grant via University of California - Year 5) | National Institutes of Health | 01 Jul 2014 | 30 Jun 2015 |
| Optimisation of sampling strategies for improving sensitivity of M. bovis detection by PCR (SE3280) - (Extension to RLFEW3011) | Department for Environment, Food and Rural Affairs | 19 Aug 2014 | 18 Oct 2014 |
| Continued development of M. bovis detection in badger faeces by PCR (DEFRA extension RLFEW3011) | Department for Environment, Food and Rural Affairs | 08 Feb 2014 | 19 Aug 2014 |
| Strategic Environmental Science Capital Call | NERC | 01 Jan 2014 | 30 Jun 2014 |
| NIH grant via University of California - Year 4 | National Institutes of Health | 01 Jul 2013 | 30 Jun 2014 |
| Development of Metaproteomics for In-situ Investigation of Microbial Activity both in Vivo and in Soil and Faeces | BBSRC | 01 May 2010 | 30 Apr 2014 |
| METAEXPLORE- Metagenomics for bioexploration- Tools and application | EU | 01 May 2009 | 30 Apr 2014 |
| Proposed extension to RLFEW3011 (30437)Optimisation of sampling strategies for improving sensitivity of M. bovis detection by PCR | Department for Environment, Food and Rural Affairs | 12 Nov 2013 | 11 Feb 2014 |
| Unrestricted Research Grant from Biome Bioplastics Ltd | Biome Bioplastics Ltd | 15 Jul 2013 | 31 Jan 2014 |
| NIH Grant via University of California: Year 3 | National Institutes of Health | 01 Jul 2012 | 30 Jun 2013 |
| Optimisation of sampling strategies for improving sensitivity of M. bovis detection by PCR | Department for Environment, Food and Rural Affairs | 01 Sep 2011 | 30 Nov 2012 |
| Studentship Luci Witcomb - In situ analysis of the microbial community associated with footrot of sheep | Pfizer Limited | 01 Oct 2008 | 30 Sep 2012 |
| Tuberculosis epidemiology and novel transmission routes in rural Tanzania (Year 2) | National Institutes of Health | 01 Jul 2011 | 30 Jun 2012 |
| Supplement to: NIH Grant via University of California: Year 2 | National Institutes of Health | 01 Jul 2011 | 30 Jun 2012 |
| The ecology of protist associated human pathogens | NERC | 01 Mar 2011 | 31 May 2012 |
| Global Metabolic Switching in Streptomyces Coelicolor. | BBSRC | 01 Dec 2006 | 17 Nov 2011 |
| BBSRC India Partnering Award (IndiaPA) 2008 | BBSRC | 01 Sep 2009 | 31 Aug 2011 |
| Tuberculosis epidemiology and novel transmission routes in rural Tanzania | National Institutes of Health | 07 Jul 2010 | 30 Jun 2011 |
| A Molecular Epidemiological Approach to Combating Footrot, an Endemic Disease of Sheep. | BBSRC | 01 Apr 2007 | 31 Mar 2011 |
| Intra- and extra-cellular mechanisms affecting the persistence of Mycobacterium bovis in the environment: towards molecular surveillance of bovine TB. | BBSRC | 01 May 2007 | 30 Apr 2010 |
| The impact of pollution on the evolution of antibiotic resistance in rhizobacteria. | NERC | 01 Jan 2007 | 31 Dec 2009 |
| ASEM-DUO Fellowship | Commission on Higher Education, Ministry of Education Thailand | 04 Dec 2009 | 11 Dec 2009 |
| CASE Studentship (Colette ONeill) Survival and dissemination of MRSA in the environment | Lumora Limited | 02 Oct 2006 | 01 Oct 2009 |
| SE3231 - Validation and Epidemiological Application of Molecular Methods for Monitoring M Bovis Survival and Dissemination in the environment | Department for Environment, Food and Rural Affairs | 21 Jun 2007 | 20 Jun 2008 |
| Evolution of disease: current patterns and future trends | National Institutes of Health | 01 Sep 2003 | 31 Aug 2007 |
| Evolution of disease: current patterns and future trends | National Institutes of Health | 01 May 2003 | 01 May 2007 |
| The Biology of Environmental Mycobacterium bovis, and its significance to the epidemiology of Bovine TB | BBSRC | 01 Feb 2004 | 31 Jan 2007 |
| INDEX - STREP | EU | 01 Jan 2004 | 31 Dec 2006 |
| Vacation Student | Lumora Limited | 19 Jun 2006 | 22 Sep 2006 |
| A Multidisciplinary study of Salmonella-protozoa interactions on surfaces, liquid culture and soil:bacterial phenotype dynamics. | BBSRC | 16 Feb 2006 | 14 Aug 2006 |
| Dissemination of Bacterial Genes (qc) Encoding Resistance to Quaternary Ammonium Compounds - CASE Award - Aileen Rahilly | Wyeth | 01 Oct 2002 | 30 Sep 2005 |
| Real time PCR & high throughput sequencing facilities for biomedical research, microbiology and cell biology | BBSRC | 01 Oct 2003 | 30 Jun 2004 |
| Rates and quantities of carbon flow through mycorrhizal mycelium to soil bacteria and fungal-feeders: Effects of micro-arthropod diversity | NERC | 01 Dec 2003 | 31 Mar 2004 |
| Royal Society Conference Grant | Royal Society | 01 Dec 2003 | 31 Dec 2003 |