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Professor Alfonso Jaramillo

Job Title
Professor of Synthetic Biology
Life Sciences
Web Link
Research Interests

Engineering organism-specific virus-like antibiotics. Engineering synthetic RNA circuits in living cells.


After a PhD in Particle Physics (1999), AJ he worked on the computational design of proteins, using molecular modeling techniques. Afterwards, after moving as Assistant Professor to Ecole Polytechnique, he developed computational design methods for metabolic networks, transcriptional networks, and particularly RNA networks. In 2009, after moving to CNRS-Genopole as senior researcher, he started his experimental microbiology lab where he could validate experimentally his computational methodologies. He then developed and used automated microscopy and microfluidics chips for single-cell validations. In 2013, he moved to the University of Warwick as Full Professor, where he is developing new cell-culture bioreactors for directed evolution, which he applies to engineer the first synthetic bacteriophage. He also is developing a novel gene regulation relying on RNA. He has coordinated several Synthetic Biology international consortia and he is member of the editorial boards of ACS Synthetic Biology and the J. of Biol. Engineering.

Title Funder Award start Award end
Warwick Integrative Synthetic Biology Centre (WISB) extension - related to 46082 BBSRC 01 Apr 2020 31 Mar 2022
EVO-ENGINE: A directed evolution engine for engineering proteins and logic gates BBSRC 01 Oct 2017 30 Sep 2021
Warwick Integrative Synthetic Biology Centre (WISB) BBSRC 14 Nov 2014 31 May 2020
MetaRNA - RNA-based technologies for single-cell metabolite analysis (Marie Curie ITN) European Commission 01 Jun 2015 30 Jun 2019
PROMYS: Programming synthetic networks for bio-based production of value chemicals EU 01 Jan 2014 31 Dec 2017
General-Purpose Programmable Evolution Machine on a Chip (EVOPROG) EU 01 Jan 2014 31 Dec 2016
Engineering bacterial circuits BBSRC 22 Jun 2015 28 Sep 2015
iGEM Glasgow student stipend competition February 2014 - University of Glasgow 23 Jun 2014 30 Sep 2014

Research themes:

Biomedical Science
Synthetic Biology and Biotechnology