Job Title
Reader
Department
Life Sciences
Phone
024 765 28144
Email
Web Link
Research Interests
To flourish plants need to adapt their growth and development in response to changes in their environment. Great progress has been made in determining the mechanisms of signal perception and an essential part of subsequent responses is rapid alteration of cellular membranes and the cell wall. Beyond transport of materials, the internalization and secretion of plasma membrane receptors can regulate signal duration and create local signal gradients. Thus, the trafficking of vesicles within a cell can be viewed as regulating overall cellular output. The mechanisms of how signal pathways and membrane trafficking events interact are largely unknown, but substantial rearrangements occur quickly, likely using pre-formed proteins.
The question my research seeks to address is 'how are the mechanisms of membrane trafficking involved in normal growth and development, adapted for responses to biotic and abiotic stress?' My objective is to identify components recruited to responsive trafficking mechanisms and provide targets to uncouple negative impacts on plant growth during adaptation to stress.
My group uses the model plant Arabidopsis thaliana, advanced proteomics, confocal microscopy and biochemistry to identify protein complexes and post-translational modifications at the interface between signal perception and responsive trafficking.
Biography
Reader, School of Life Sciences, University of Warwick. 2013-present
Head of Proteomics at The Sainsbury Laboratory, Norwich, 2005-2013
Post-doctoral researcher Targeting of EDS1/PAD4 resistance signalling complexes by bacterial effector proteins Imperial College, London. 2004-2005
Post-doctoral researcher "Comparative analysis of the defence proteome of Arabidopsis thaliana" Imperial College Wye Campus 2001-2004
Post-doctoral researcher "The impact of transgenes for herbivore and virus resistance on the weediness of crop relatives" at the Centre for Ecology and Hydrology, Dorset. 1999-2001
PhD "Purification and Sequencing of Myrosinase from the Cabbage Aphid". Imperial College Wye campus 1999
MSc Applied Plant Sciences. Imperial College Wye campus 1995
BSc (Hons) Chemistry & Biochemistry. Imperial College London 1990-1993
My publication and citation lists can be viewed at ResearcherID (B-5227-2009)
- Lidbury, Ian, Borsetto, Chiara, Murphy, Andrew, Bottrill, Andrew R., Jones, Alexandra M., Bending, G. D., Hammond, John P., Chen, Yin, Wellington, Elizabeth M. H., Scanlan, David J., 2021. Niche-adaptation in plant-associated Bacteroidetes favours specialisation in organic phosphorus mineralisation. ISME Journal, 15, pp. 1040-1055
- Cai, Weigang, Egertová, Michaela, Zampronio, Cleidiane G., Jones, Alexandra M., Elphick, Maurice R., 2021. Molecular identification and cellular localisation of a corticotropin-releasing hormone type neuropeptide in an echinoderm. Neuroendocrinology
- Cecchetti, Cristina, Scull, Nicola J., Mohan, Thotegowdanapalya C., Alguel, Yilmaz, Jones, Alexandra M. C., Cameron, Alexander D., Byrne, Bernadette, 2021. Transfer of stabilising mutations between different secondary active transporter families. FEBS Open Bio, 11 (6), pp. 1685-1694
- Saouros, Savvas, Mohan, Thotegowdanapalya C., Cecchetti, Cristina, Lehmann, Silke, Barritt, Joseph D., Scull, Nicola J., Simpson, Paul, Alguel, Yilmaz, Cameron, Alexander D., Jones, Alexandra M. E., Byrne, Bernadette, 2021. Structural and functional insights into the mechanism of action of plant borate transporters. Scientific Reports, 11 (1)
- Petre, Benjamin, Contreras, Mauricio P., Bozkurt, Tolga O., Schattat, Martin H., Sklenar, Jan, Schornack, Sebastian, Abd-El-Haliem, Ahmed, Castells-Graells, Roger, Lozano-Durán, Rosa, Dagdas, Yasin F., Menke, Frank L. H., Jones, Alexandra M. E., Vossen, Jack H., Robatzek, Silke, Kamoun, Sophien, Win, Joe, 2021. Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process. The Plant Cell, 33 (5), pp. 1447-1471
- Vong, Yin Ho, Sivashanmugam, Lavanya, Leech, Rebecca, Zaucker, Andreas, Jones, Alexandra M., Sampath, Karuna, 2021. The RNA-binding protein Igf2bp3 is critical for embryonic and germline development in zebrafish. PLoS Genetics, 17 (7)
- Tinoco, Ana B., Barreiro-Iglesias, Antón, Yañez Guerra, Luis Alfonso, Delroisse, Jérôme, Zhang, Ya, Gunner, Elizabeth F., Zampronio, Cleidiane G., Jones, Alexandra M., Egertová, Michaela, Elphick, Maurice R., 2021. Ancient role of sulfakinin/cholecystokinin-type signalling in inhibitory regulation of feeding processes revealed in an echinoderm. eLife, 10
- Bender, Kyle W., Couto, Daniel, Kadota, Yasuhiro, Macho, Alberto P., Sklenar, Jan, Derbyshire, Paul, Bjornson, Marta, DeFalco, Thomas A., Petriello, Annalise, Font Farre, Maria, Schwessinger, Benjamin, Ntoukakis, Vardis, Stransfeld, Lena, Jones, Alexandra M. E., Menke, Frank L. H., Zipfel, Cyril, 2021. Activation loop phosphorylaton of a non-RD receptor kinase initiates plant innate immune signaling. Proceedings of the National Academy of Sciences of the United States of America, 118 (38)
- Baxter, Laura, Roy, Proyash, Picot, Emma, Watts, Jess, Jones, Alexandra M., Wilkinson, Helen, Schäfer, Patrick, Gifford, Miriam L., Lagunas, Beatriz, 2021. Comparative genomics across three ensifer species using a new complete genome sequence of the Medicago symbiont Sinorhizobium (Ensifer) meliloti WSM1022. Microorganisms, 9 (12)
- Jacomin, Anne-Claire, Petridi, Stavroula, Di Monaco, Marisa, Bhujabal, Zambarlal, Jain, Ashish, Mulakkal, Nitha Charles, Palara, Anthimi, Powell, Emma L., Chung, Bonita, Zampronio, Cleidiane, Jones, Alexandra M., Cameron, Alexander, Johansen, Terje, Nezis, Ioannis P., 2020. Regulation of expression of autophagy genes by Atg8a-interacting partners Sequoia, YL-1 and Sir2 in Drosophila. Cell Reports, 31 (8)
- Saouros, Savvas, Cecchetti, Cristina, Jones, Alexandra M., Cameron, Alexander, Byrne, Bernadette, 2020. Strategies for successful isolation of a eukaryotic transporter. Protein Expression and Purification, 166
- Yañez-Guerra, Luis Alfonso, Zhong, Xingxing, Moghul, Ismail, Butts, Thomas, Zampronio, Cleidiane G., Jones, Alexandra M., Mirabeau, Olivier, Elphick, Maurice R., 2020. Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling. eLife, 9
- Zhang, Ya, Yañez Guerra, Luis Alfonso, Egertová, Michaela, Zampronio, Cleidiane G., Jones, Alexandra M., Elphick, Maurice R., 2020. Molecular and functional characterization of somatostatin-type signalling in a deuterostome invertebrate. Open Biology, 10 (9)
- Syed, Junetha, Palani, Saravanan, Clarke, Scott T., Asad, Zainab, Bottrill, Andrew R., Jones, Alexandra M.E., Sampath, Karuna, Balasubramanian, Mohan K., 2019. Expanding the zebrafish genetic code through site-specific introduction of azido-lysine, bicyclononyne-lysine, and diazirine-lysine. International Journal of Molecular Sciences, 20 (10)
- Palani, Saravanan, Köster, Darius, Hatano, Tomoyuki, Kamnev, Anton, Kanamaru, Taishi, Brooker, Holly R., Hernandez-Fernaud, Juan Ramon, Jones, Alexandra M. E., Millar, Jonathan B. A., Mulvihill, Daniel P., Balasubramanian, Mohan K., 2019. Phosphoregulation of tropomyosin is crucial for actin cable turnover and division site placement. Journal of Cell Biology, 218 (11), pp. 3548-3559
- Cai, Weigang, Kim, Chan-Hee, Go, Hye-Jin, Egertová, Michaela, Zampronio, Cleidiane, Jones, Alexandra M., Park, Nam Gyu, Elphick, Maurice R., 2018. Biochemical, anatomical, and pharmacological characterization of calcitonin-type neuropeptides in starfish : discovery of an ancient role as muscle relaxants. Frontiers in Neuroscience, 12
- Mohan, Thotegowdanapalya C., Jones, Alexandra M., 2018. Determination of boron content using a simple and rapid miniaturized curcumin assay. Bio-protocol, 7 (2)
- Waghmare, Sakharam, Lileikyte, Edita, Karnik, Rucha Anil, Goodman, Jennifer, Blatt, Mike R., Jones, Alexandra M., 2018. SNAREs SYNTAXIN OF PLANTS 121 (SYP121) and SYP122 mediate the secretion of distinct cargo subsets. Plant Physiology, 4, pp. 1679-1688
- Goodman, Jennifer, Zampronio, Cleidiane, Jones, Alexandra M., Hernandez-Fernaud, Juan Ramon, 2018. Updates of the in-gel digestion method for protein analysis by mass spectrometry. Proteomics
- Hatano, Tomoyuki, Alioto, Salvatore, Roscioli, Emanuele, Palani, Saravanan, Clarke, Scott T., Kamnev, Anton, Hernandez Fernaud, Juan Ramon, Sivashanmugam, Lavanya, Chapa y Lazo, Bernardo, Jones, Alexandra M., Robinson, Robert C., Sampath, Karuna, Mishima, Masanori, McAinsh, Andrew D., Goode, Bruce L., Balasubramanian, Mohan K., 2018. Rapid production of pure recombinant actin isoforms in Pichia pastoris. Journal of Cell Science, 131 (8)
- Lin, Ming, Egertová, Michaela, Zampronio, Cleidiane G., Jones, Alexandra M., Elphick, Maurice R., 2018. Functional characterization of a second pedal peptide/orcokinin-type neuropeptide signaling system in the starfish Asterias rubens. Journal of Comparative Neurology, 526 (5), pp. 858-876
- Lidbury, Ian, Murphy, Andrew, Fraser, Tandra D., Bending, G. D., Jones, Alexandra M., Moore, Jonathan D., Goodall, Andrew, Tibbetts, Mark, Hammond, John P., Scanlan, David J., Wellington, E. M. H., 2017. Identification of extracellular glycerophosphodiesterases in Pseudomonas and their role in soil organic phosphorus remineralisation. Scientific Reports, 7 (1)
- Lin, Ming, Egertová, Michaela, Zampronio, Cleidiane, Jones, Alexandra M., Elphick, Maurice R., 2017. Pedal peptide/orcokinin-type neuropeptide signaling in a deuterostome : the anatomy and pharmacology of starfish myorelaxant peptide in Asterias rubens. Journal of Comparative Neurology, 525 (18), pp. 3890-3917
- Lidbury, Ian, Fraser, Tandra, Murphy, Andrew, Scanlan, David J., Bending, G. D. (Gary D.), Jones, Alexandra M., Moore, Jonathan D., Goodall, Andrew, Tibbett, Mark, Hammond, John P., Wellington, E. M. H., 2017. The ?known' genetic potential for microbial communities to degrade organic phosphorus is reduced in low-pH soils.. MicrobiologyOpen
- Lidbury, Ian, Murphy, Andrew, Scanlan, David J., Bending, G. D., Jones, Alexandra M., Moore, Jonathan D., Goodall, Amanda, Hammond, John P., Wellington, E. M. H., 2016. Comparative genomic, proteomic and exoproteomic analyses of three Pseudomonas strains reveals novel insights into the phosphorus scavenging capabilities of soil bacteria. Environmental Microbiology, 18 (10), pp. 3535-3549
- Üstün, Suayib, Sheikh, Arsheed, Gimenez-Ibanez , Selena, Jones, Alexandra M., Ntoukakis, Vardis, Börnke, Frederik, 2016. The proteasome acts as a hub for plant immunity and is targeted by Pseudomonas type-III effectors. Plant Physiology, 172 (3), pp. 1941-1958
- Chaparro-Garcia, Angela, Schwizer, Simon, Sklenar, Jan, Yoshida, Kentaro, Petre, Benjamin, Bos, Jorunn I. B., Schornack, Sebastian, Jones, Alexandra M., Bozkurt, Tolga O., Kamoun, Sophien, 2015. Phytophthora infestans RXLR-WY Effector AVR3a Associates with Dynamin-Related Protein 2 Required for Endocytosis of the Plant Pattern Recognition Receptor FLS2. PLoS One, 10 (9)
- Shao, Nan, Singh, N. Sadanands, Slade, Susan E., Jones, Alexandra M., Balasubramanian, Mohan K., 2015. Site specific genetic incorporation of azidophenylalanine in Schizosaccharomyces pombe. Scientific Reports, 5, pp. 1-9
- Heard, William, Sklenar, Jan, Tomé, Daniel F. A., Robatzek, Silke, Jones, Alexandra M., 2015. Identification of regulatory and cargo proteins of endosomal and secretory pathways in Arabidopsis thaliana by proteomic dissection. Molecular & Cellular Proteomics, 14 (7), pp. 1796-1813
- Wirthmueller, Lennart, Roth, Charlotte, Fabro, Georgina, Caillaud, Marie-Cécile, Rallapalli, Ghanasyam, Asai, Shuta, Sklenar, Jan, Jones, Alexandra M., Wiermer, Marcel, Jones, Jonathan D. G., Banfield, Mark J., 2015. Probing formation of cargo/importin-a transport complexes in plant cells using a pathogen effector. The Plant Journal, 81 (1), pp. 40-52
- Kadota, Yasuhiro, Sklenar, Jan, Derbyshire, Paul, Stransfeld, Lena, Asai, Shuta, Ntoukakis, Vardis, Jones, Jonathan D. G., Shirasu, Ken, Menke, Frank, Jones, Alexandra M., Zipfel, Cyril, 2014. Direct regulation of the NADPH oxidase RBOHD by the PRR-associated kinase BIK1 during plant immunity. Molecular Cell, 54 (1), pp. 43-55
- Piquerez, Sophie J., Balmuth, Alexi L., Sklenár, Jan, Jones, Alexandra M., Rathjen, John P., Ntoukakis, Vardis, 2014. Identification of post-translational modifications of plant protein complexes. Journal of Visualized Experiments
- Caillaud, Marie-Cécile, Wirthmueller, Lennart, Sklenar, Jan, Findlay, Kim, Piquerez, Sophie J. M., Jones, Alexandra M., Robatzek, Silke, Jones, Jonathan D. G., Faulkner, Christine, 2014. The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. PLoS Pathogens, 10 (11)
- Wilhelm, Thomas, Jones, Alexandra M., 2014. Identification of related peptides through the analysis of fragment ion mass shifts. Journal of Proteome Research, 13 (9), pp. 4002-4011
- Dong, S., Stam, R., Cano, L. M., Song, J., Sklenar, J., Yoshida, K., Bozkurt, T. O., Oliva, R., Liu, Z., Tian, M., Win, J., Banfield, M. J., Jones, Alexandra M., van der Hoorn, R. A. L., Kamoun, S., 2014. Effector specialization in a lineage of the irish potato famine pathogen. Science, 343 (6170), pp. 552-555
- Jones, Alexandra M., Monaghan, Jacqueline, Ntoukakis, Vardis, 2013. Editorial : mechanisms regulating immunity in plants. Frontiers in Plant Science, 4
- Ntoukakis, Vardis, Balmuth, Alexi L., Mucyn, Tatiana S., Gutierrez, Jose R., Jones, Alexandra M., Rathjen, John P., 2013. The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation. PLoS Pathogens, Vol.9 (No.1)
- Pais, Marina, Win, Joe, Yoshida, Kentaro, Etherington, Graham J., Cano, Liliana M., Raffaele, Sylvain, Banfield, Mark J., Jones, Alexandra M., Kamoun, Sophien, Saunders, Diane G. O., 2013. From pathogen genomes to host plant processes : the power of plant parasitic oomycetes. Genome Biology, 14 (6)
- Liebrand, T. W. H., van den Berg, G. C. M., Zhang, Z., Smit, P., Cordewener, J. H. G., America, A. H. P., Sklenar, J., Jones, Alexandra M., Tameling, W. I. L., Robatzek, S., Thomma, B. P. H. J., Joosten, M. H. A. J., 2013. Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infection. Proceedings of the National Academy of Sciences of the United States of America, 110 (24), pp. 10010-10015
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Jones, Alexandra M., Aebersold, Ruedi, Ahrens, Christian H., Apweiler, Rolf, Baerenfaller, Katja, Baker, Mark, Bendixen, Emøke, Briggs, Steve, Brownridge, Philip, Brunner, Erich, Daube, Michael, Deutsch, Eric W., Grossniklaus, Ueli, Heazlewood, Joshua, Hengartner, Michael O., Hermjakob, Henning, Jovanovic, Marko, Lawless, Craig, Lochnit, Günter, Martens, Lennart et al (Select to open full list), 2012. The HUPO initiative on model organism proteomes, iMOP. Proteomics, 12 (3), pp. 340-345
- Greer, E., Martin, A. C., Pendle, A., Colas, I., Jones, Alexandra M., Moore, G., Shaw, P., 2012. The Ph1 locus suppresses Cdk2-type activity during premeiosis and meiosis in wheat. The Plant Cell, 24 (1), pp. 152-162
- Liebrand, T. W. H., Smit, P., Abd-El-Haliem, A., de Jonge, R., Cordewener, J. H. G., America, A. H. P., Sklenar, J., Jones, Alexandra M., Robatzek, S., Thomma, B. P. H. J., Tameling, W. I. L., Joosten, M. H. A. J., 2012. Endoplasmic reticulum-quality control chaperones facilitate the biogenesis of Cf receptor-like proteins involved in pathogen resistance of tomato. Plant Physiology, 159 (4), pp. 1819-1833
- Göhre, Vera, Jones, Alexandra M., Sklenár, Jan, Robatzek, Silke, Weber, Andreas P. M., 2012. Molecular crosstalk between PAMP-triggered immunity and photosynthesis. Molecular Plant-Microbe Interactions, 25 (8), pp. 1083-1092
- van Damme, Mireille, Bozkurt, Tolga O., Cakir, Cahid, Schornack, Sebastian, Sklenar, Jan, Jones, Alexandra M., Kamoun, Sophien, 2012. The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells. PLoS Pathogens, 8 (8)
- Fan, Jun, Mohareb, Fady, Jones, Alexandra M., Bessant, Conrad, 2012. MRMaid : the SRM assay design tool for Arabidopsis and other species. Frontiers in Plant Science, 3
- Guttman, David S., Schwessinger, Benjamin, Roux, Milena, Kadota, Yasuhiro, Ntoukakis, Vardis, Sklenar, Jan, Jones, Alexandra M., Zipfel, Cyril, 2011. Phosphorylation-Dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-Like Kinase BAK1. PLoS Genetics, Vol. 7 (No. 4)
- Roux, Milena, Schwessinger, Ben, Albrecht, C. (Catherine), Chinchilla, D. (Delphine), Jones, Alexandra M., Holton, Nicholas, Malinovsky, F. G., Tör, Mahmut, de Vries, Sacco, Zipfel, Cyril, 2011. The Arabidopsis leucine-rich repeat receptor-like kinases BAK1/SERK3 and BKK1/SERK4 are required for innate immunity to hemibiotrophic and biotrophic pathogens. The Plant Cell, Vol.23 (No.6), pp. 2440-2455
- Win, Joe, Kamoun, Sophien, Jones, Alexandra M., 2011. Purification of effector?target protein complexes via transient expression in Nicotiana benthamiana. Methods in Molecular Biology, 712, pp. 181-194
- Jones, Alexandra M., Nühse, Thomas S., 2011. Phosphoproteomics using iTRAQ. Methods in Molecular Biology, 779, pp. 287-302
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Joshi, H. J., Hirsch-Hoffmann, M., Baerenfaller, K., Gruissem, W., Baginsky, S., Schmidt, R., Schulze, W. X., Sun, Q., van Wijk, K. J., Egelhofer, V., Wienkoop, S., Weckwerth, W., Bruley, C., Rolland, N., Toyoda, T., Nakagami, H., Jones, Alexandra M., Briggs, S. P., Castleden, I., Tanz, S. K. et al (Select to open full list), 2011. MASCP Gator : an aggregation portal for the visualization of arabidopsis proteomics data. Plant Physiology, 155 (1), pp. 259-270
- Lee, Sarah E., Elphick, Lucy M., Kramer, Holger B., Jones, Alexandra M., Child, Emma S., Anderson, Alexandra A., Bonnac, Laurent, Suwaki, Natsuko, Kessler, Benedikt M., Gouverneur, Véronique, Mann, David J., 2011. The chemoselective one-step alkylation and isolation of thiophosphorylated Cdk2 substrates in the presence of native cysteine. ChemBioChem, 12 (4), pp. 633-640
- Bozkurt, T. O., Schornack, S., Win, J., Shindo, T., Ilyas, M., Oliva, R., Cano, L. M., Jones, Alexandra M., Huitema, E., van der Hoorn, R. A. L., Kamoun, S., 2011. Phytophthora infestans effector AVRblb2 prevents secretion of a plant immune protease at the haustorial interface. Proceedings of the National Academy of Sciences of the United States of America, 108 (51), pp. 20832-20837
- Gutierrez, Jose R., Balmuth, Alexi L., Ntoukakis, Vardis, Mucyn, Tatiana S., Gimenez-Ibanez, Selena, Jones, Alexandra M., Rathjen, John P., 2010. Prf immune complexes of tomato are oligomeric and contain multiple Pto-like kinases that diversify effector recognition. The Plant Journal, Vol. 61 (No. 3), pp. 507-518
- Durek, P., Schmidt, R., Heazlewood, J. L., Jones, Alexandra M., MacLean, Daniel, Nagel, Alexander, Kersten, Birgit, Schulze, W. X., 2010. PhosPhAt : the Arabidopsis thaliana phosphorylation site database : an update. Nucleic Acids Research, 38 (Supplement 1), pp. D828-D834
- Petutschnig, E. K., Jones, Alexandra M., Serazetdinova, L., Lipka, U., Lipka, V., 2010. The lysin motif receptor-like kinase (LysM-RLK) CERK1 is a major chitin-binding protein in Arabidopsis thaliana and subject to chitin-induced phosphorylation. Journal of Biological Chemistry, 285 (37), pp. 28902-28911
- Yelina, N. E., Smith, L. M., Jones, Alexandra M., Patel, K., Kelly, K. A., Baulcombe, D. C., 2010. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Proceedings of the National Academy of Sciences of the United States of America, 107 (31), pp. 13948-13953
- Parker, Jennifer L., Jones, Alexandra M., Serazetdinova, Liliya, Saalbach, Gerhard, Bibb, Mervyn J., Naldrett, Mike J., 2010. Analysis of the phosphoproteome of the multicellular bacterium Streptomyces coelicolor A3(2) by protein/peptide fractionation, phosphopeptide enrichment and high-accuracy mass spectrometry. Proteomics, 10 (13), pp. 2486-2497
- Manzano, D., Marquardt, S., Jones, Alexandra M., Baurle, I., Liu, F., Dean, C., 2009. Altered interactions within FY/AtCPSF complexes required for Arabidopsis FCA-mediated chromatin silencing. Proceedings of the National Academy of Sciences of the United States of America, 106 (21), pp. 8772-8777
- Huang, Linfeng, Jones, Alexandra M., Searle, Iain, Patel, Kanu, Vogler, Hannes, Hubner, Nina C, Baulcombe, David C, 2009. An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature Structural & Molecular Biology, 16 (1), pp. 91-93
- Ntoukakis, Vardis, Mucyn, T. S., Gimenez-Ibanez, S., Chapman, H. C., Gutierrez, J. R., Balmuth, Alexi L., Jones, Alexandra M., Rathjen, J. P., 2009. Host inhibition of a bacterial virulence effector triggers immunity to infection. Science, 324 (5928), pp. 784-787
- Kaffarnik, F. A. R., Jones, Alexandra M., Rathjen, J. P., Peck, S. C., 2009. Effector proteins of the bacterial pathogen pseudomonas syringae alter the extracellular proteome of the host plant, Arabidopsis thaliana. Molecular & Cellular Proteomics, 8 (1), pp. 145-156
- Bush, Maxwell S., Hutchins, Andrew P., Jones, Alexandra M., Naldrett, Mike J., Jarmolowski, Artur, Lloyd, Clive W., Doonan, John H., 2009. Selective recruitment of proteins to 5' cap complexes during the growth cycle in Arabidopsis. The Plant Journal, 59 (3), pp. 400-412
- Jones, Alexandra M., MacLean, Daniel, Studholme, David J., Serna-Sanz, Antonio, Andreasson, Erik, Rathjen, John P., Peck, Scott C., 2009. Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis thaliana. Journal of Proteomics, 72 (3), pp. 439-451
- MacLean, Daniel, Burrell, Michael A., Studholme, David J., Jones, Alexandra M., 2008. PhosCalc : A tool for evaluating the sites of peptide phosphorylation from Mass Spectrometer data. BMC Research Notes, 1 (1)
- Traka, Maria H., Gasper, Amy V., Melchini, Antonietta, Bacon, James R., Needs, Paul W., Frost, Victoria, Chantry, Andrew, Jones, Alexandra M., Ortori, Catharine A., Barrett, David A., Ball, Richard Y., Mills, Robert D., Mithen, Richard F., 2008. Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One, 3 (7)
- De Lucia, F., Crevillen, P., Jones, Alexandra M., Greb, T., Dean, C., 2008. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proceedings of the National Academy of Sciences of the United States of America, 105 (44), pp. 16831-16836
- Whiteman, Sally-Anne, Serazetdinova, Liliya, Jones, Alexandra M., Sanders, Dale, Rathjen, John, Peck, Scott C., Maathuis, Frans J. M., 2008. Identification of novel proteins and phosphorylation sites in a tonoplast enriched membrane fraction of Arabidopsis thaliana. Proteomics, 8 (17), pp. 3536-3547
- Romero-Puertas, M. C., Laxa, M., Matte, A., Zaninotto, F., Finkemeier, I., Jones, Alexandra M., Perazzolli, M., Vandelle, E., Dietz, K.-J., Delledonne, M., 2007. S-nitrosylation of peroxiredoxin II E promotes peroxynitrite-mediated tyrosine nitration. The Plant Cell, 19 (12), pp. 4120-4130
- Nühse, Thomas S., Bottrill, Andrew R., Jones, Alexandra M., Peck, Scott C., 2007. Quantitative phosphoproteomic analysis of plasma membrane proteins reveals regulatory mechanisms of plant innate immune responses. The Plant Journal, 51 (5), pp. 931-940
- Herr, A. J., Molnar, A., Jones, Alexandra M., Baulcombe, D. C., 2006. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 103 (41), pp. 14994-15001
- Lowe, Andrew J., Jones, Alexandra M., Raybould, Alan F., Trick, Martin, Moule, Carolyn L., Edwards, Keith J., 2002. Transferability and genome specificity of a new set of microsatellite primers among Brassica species of the U triangle. Molecular Ecology Notes, 2 (1), pp. 7-11
- Bridges, M., Jones, Alexandra M., Bones, A. M., Hodgson, C., Cole, R., Bartlet, E., Wallsgrove, R., Karapapa, V. K., Watts, N., Rossiter, J. T., 2002. Spatial organization of the glucosinolate-myrosinase system in brassica specialist aphids is similar to that of the host plant. Proceedings of the Royal Society B: Biological Sciences, 269 (1487), pp. 187-191
- Jones, Alexandra M., Winge, P., Bones, A. M., Cole, R., Rossiter, J. T., 2002. Characterization and evolution of a myrosinase from the cabbage aphid Brevicoryne brassicae. Insect Biochemistry and Molecular Biology, 32 (3), pp. 275-284
- Jones, Alexandra M., Bridges, M., Bones, A. M., Cole, R., Rossiter, J. T., 2001. Purification and characterisation of a non-plant myrosinase from the cabbage aphid Brevicoryne brassicae (L.). Insect Biochemistry and Molecular Biology, 31 (1), pp. 1-5
- Davenport, I. J., Wilkinson, M. J., Mason, D. C., Charters, Y. M., Jones, Alexandra M., Allainguillaume, J., Butler, H. T., Raybould, A. F., 2000. Quantifying gene movement from oilseed rape to its wild relatives using remote sensing. International Journal of Remote Sensing, 21 (18), pp. 3567-3573
- Wilkinson, M. J., Davenport, I. J., Charters, Y. M., Jones, Alexandra M., Allainguillaume, J., Butler, H. T., Mason, D. C., Raybould, A. F., 2000. A direct regional scale estimate of transgene movement from genetically modified oilseed rape to its wild progenitors. Molecular Ecology, 9 (7), pp. 983-991
- Raybould, A. F., Alexander, M. J., Mitchell, E., Thurston, M. I., Pallett, D. W., Hunter, P., Walsh, J. A., Edwards, M. L., Jones, Alexandra M., Moyes, C. L., Gray, A. J., Cooper, J. I., 2003. The ecology of turnip mosaic virus in wild populations of Brassica species. The Fifteenth Special Symposium of the British Ecological Society, 17-19 Sep 2001, Published in Genes in the Environment. The Fifteenth Special Symposium of the British Ecological Society, pp. 226-244
- Bender, Kyle W., Couto, Daniel, Kadota, Yasuhiro, Macho, Alberto P., Sklenar, Jan, Bjornson, Marta, Petriello, Annalise, Farre, Maria Font, Schwessinger, Benjamin, Ntoukakis, Vardis, Stransfeld, Lena, Jones, Alexandra M. E., Menke, Frank L. H., Zipfel, Cyril, 2021. Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling [pre-print]. bioRxiv
- Saouros, Savvas, Mohan, Thotegowdanapalya C., Cecchetti, Cristina, Lehmann, Silke, Barritt, Joseph D., Scull, Nicola J., Simpson, Paul, Alguel, Yilmaz, Cameron, Alexander D., Jones, Alexandra M. E., Byrne, Bernadette, 2020. Structural and functional insights into the mechanism of action of plant boron transporters [pre-print]. bioRxiv
- Vong, Yin Ho, Sivashanmugam, Lavanya, Zaucker, Andreas, Jones, Alex, Sampath, Karuna, 2020. The RNA-binding protein Igf2bp3 is critical for embryonic and germline development in zebrafish [pre-print]. bioRxiv
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| Title | Funder | Award start | Award end |
|---|---|---|---|
| Resource Only Strategic Equipment: the Warwick Analytical Science Centre (Full) | EPSRC | 01 Sep 2020 | 31 Aug 2024 |
| Phospho-proteomic Analysis of Microbe-Associated Molecular Patterns (MAMPs) Signalling in Plant Immunity - A small MLSRF grant | Medical and Life Sciences Research Fund | 01 May 2021 | 30 Apr 2022 |
| Ion mobility mass spectrometer for proteomics facility. ALERT19 | BBSRC | 01 Jul 2020 | 30 Jun 2021 |
| Elucidating molecular level details of the plant Borate transporter structure and function | BBSRC | 03 Oct 2016 | 31 Mar 2020 |
| Phosphorus cycling in the soil-microbe-plant continuum of agri-ecosystems | BBSRC | 31 Dec 2014 | 31 Jul 2019 |
| MLSRF Mohan T Chandrashekarai | Medical and Life Sciences Research Fund | 01 Mar 2018 | 28 Feb 2019 |
| Neuropeptide function in a decentalized nervous system | BBSRC | 01 Jan 2015 | 31 Dec 2017 |
| Control of seed and organ size by a ubiquitin-mediated signalling cascade | BBSRC | 01 Oct 2013 | 30 Sep 2016 |
| Regulation of polar growth in plant roots: the interplay of signalling and vesicle trafficking | Medical and Life Sciences Research Fund | 01 Aug 2015 | 31 Jul 2016 |
| Pilot study to develop methodologies and acquire data, allowing elucidation of the coordinated control of splicing in oestrogen positive and negative breast cancer tissues | Medical and Life Sciences Research Fund | 01 Jun 2014 | 31 May 2015 |
| Developing interdisciplinary omics tools for organelle and cell type-specific analysis of Arabidopsis thaliana | New Phytologist Trust | 01 Sep 2014 | 30 Sep 2014 |