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Dr Daniel Hebenstreit

Job Title
Associate Professor
Life Sciences
024 765 74457
Web Link
Research Interests

My group is working on the mechanisms of transcriptional regulation in metazoan cells. We are interested in several aspects of this, including the interplay of epigenetics and transcription, the role of 'noise' in gene and protein expression, and the reorganization of transcriptional networks upon differentiation. To study these subjects, we are employing a systems-biology approach based on accurate experimental quantification with next-generation sequencing technologies such as mRNA-seq and ChIP-seq, studying cell population diversity with flow cytometry, and statistical and mathematical analysis of the data. We focus on the system of murine T helper cells, particularly the Th2 subtype, which provides a valuable model for mammalian cell differentiation and is experimentally accessible.

If you are interested in joining my group, please contact me per email and send me your CV. Molecular biologists, bioinformaticians, physicists, and mathematicians welcome.


Assistant Professor at University of Warwick, Coventry, UK, 2012 - now
MRC Career Development Fellow at MRC Laboratory of Molecular Biology, Cambridge, UK, 2009 - 2012
Post-doctoral fellow at the MRC Laboratory of Molecular Biology, Cambridge, UK, 2007 - 2009
BSc in Mathematics, University of Salzburg, Austria, 2007
PhD in Genetics, University of Salzburg, Austria, 2005
MSc in Genetics, University of Salzburg, Austria, 2000

Title Funder Award start Award end
Defining and exploiting the role of PML protein in innate immune responses to pathogens - MRC Research Grant MRC 01 Aug 2017 31 Jul 2020
Warwick Integrative Synthetic Biology Centre (WISB) BBSRC 14 Nov 2014 31 May 2020
Genomic scaling of transcriptional noise BBSRC 01 Jan 2014 17 Mar 2019
Establishing and optimizing quantitative single cell RNA-sequencing (scRNA-seq) Royal Society 31 Dec 2013 30 Dec 2014