Research Interests

My group is working on the mechanisms of transcriptional regulation in metazoan cells. We are interested in several aspects of this, including the interplay of epigenetics and transcription, the role of 'noise' in gene and protein expression, and the reorganization of transcriptional networks upon differentiation. To study these subjects, we are employing a systems-biology approach based on accurate experimental quantification with next-generation sequencing technologies such as mRNA-seq and ChIP-seq, studying cell population diversity with flow cytometry, and statistical and mathematical analysis of the data. We focus on the system of murine T helper cells, particularly the Th2 subtype, which provides a valuable model for mammalian cell differentiation and is experimentally accessible.

If you are interested in joining my group, please contact me per email and send me your CV. Molecular biologists, bioinformaticians, physicists, and mathematicians welcome.

Biography

Associate Professor at University of Warwick, Coventry, UK, 2017 - present
Assistant Professor at University of Warwick, Coventry, UK, 2012 - 2017
MRC Career Development Fellow at MRC Laboratory of Molecular Biology, Cambridge, UK, 2009 - 2012
Post-doctoral fellow at the MRC Laboratory of Molecular Biology, Cambridge, UK, 2007 - 2009
BSc in Mathematics, University of Salzburg, Austria, 2007
PhD in Genetics, University of Salzburg, Austria, 2005
MSc in Genetics, University of Salzburg, Austria, 2000

Research Projects

Publications