Research Interests
Elizabeth Creak Chair in Food Security
My research interests centre around plant-microbe interactions with a predominate focus on host responses to pathogenic bacteria. We also study the mechanisms underpinning biocontrol and plant growth promotion conferred by beneficial fungi and have interest in applying our general expertise to emerging tree diseases.
We deploy interdisciplinary approaches such as real time imaging, physiology, reverse genetics, a range of "omics" techniques (including untargeted metabolomics) and network inference modelling to study the dynamics and molecular basis of three fundamental outcomes of plant-pathogen interactions; suppression of defence, gene-for-gene resistance and the early events involved in propagating systemic immunity.
Notable contributions to the field include the first map-based cloning of a dual recognition resistance gene, RPM1 ; the first evolutionary study of an R gene; the first real time measurement of in planta cytosolic calcium changes during a resistance response; the first functional characterisation of an evolutionarily conserved plant inhibitor of apoptosis; the first description on how pathogen effector proteins modulate defence networks. More recently we have studied phytohormone cross talk in moulding the outcome of plant defences responses. We are particularly interested in exploring; (i) the key role ABA plays in hijacking plant defence and (ii) an unexpected contribution of jasmonates and auxin in systemic immunity. We are currently using synthetic biology approaches to re-wire these pathways thus interfering with pathogen virulence strategies. A more recent discovery that the chloroplast is a key player in orchestrating effective innate immune responses and is targeted by pathogen effectors mechanistically links disease with yield loss.
A remarkable 40% of the proteome of the saprophytic fungus Trichoderma hamatum is unique compared to other Trichoderma spp. Using a combination of metabolomic and transcriptomic informed targeted mutagenesis, we are studying whether this additional genetic material encodes novel chemistries that contribute to T. hamatum's remarkable plant growth promotion and biocontrol activities.
Biography
PhD Biochemistry, Otago University, New Zealand. 1988
BSc (first class) Biochemistry, Otago University, New Zealand. 1983
- Schofield, Zoe, Meloni, Gabriel N., Tran, Peter, Zerfass, Christian, Sena, Giovanni, Hayashi, Yoshikatsu, Grant, Murray R., Contera, Sonia A., Minteer, Shelley D., Kim, Minsu, Prindle, Arthur, Rocha, Paulo, Djamgoz, Mustafa B. A., Pilizota, Teuta, Unwin, Patrick R., Asally, Munehiro, Soyer, Orkun S., 2020. Bioelectrical understanding and engineering of cell biology. Journal of The Royal Society Interface, 17 (166)
- Sambles, Christine, Venkatesan, Lakshmipriya, Shittu, Olanrewaju M., Harrison, James, Moore, Karen, Tripathi, Leena, Grant, Murray R., Warmington, Rachel, Studholme, David J., 2020. Genome sequencing data for wild and cultivated bananas, plantains and abacá. Data in Brief, 33
- Nakato, Gloria V., Studholme, David J., Blomme, Guy, Grant, Murray, Coutinho, Teresa A., Were, Evans M., Wicker, Emmanuel, Mahuku, George, 2020. SNP-based genotyping and whole-genome sequencing reveal previously unknown genetic diversity in Xanthomonas vasicola pv. musacearum , causal agent of banana xanthomonas wilt, in its presumed Ethiopian origin. Plant Pathology
- Sidda, John D., Song, Lijiang, Parker, Jack L., Studholme, David J., Sambles, Christine, Grant, Murray, 2020. Diversity of secoiridoid glycosides in leaves of UK and Danish ash provide new insight for ash dieback management. Scientific Reports, 10 (1)
- Drenichev, Mikhail S., Bennett, Mark, Novikov, Roman A., Mansfield, John, Smirnoff, Nick, Grant, Murray R., Mikhailov, Sergey N., 2019. A role for 3'-O-ß-D-ribofuranosyladenosine in altering plant immunity. Phytochemistry Letters, 157, pp. 128-134
- Studholme, David J., Panda, Preeti, Sanfuentes Von Stowasser, Eugenio, González, Mariela, Hill, Rowena, Sambles, Christine, Grant, Murray R., Williams, Nari M., McDougal, Rebecca L., 2019. Genome sequencing of oomycete isolates from Chile supports the New Zealand origin of Phytophthora kernoviae and makes available the first Nothophytophthora sp. genome. Molecular Plant Pathology, 20 (3), pp. 423-431
- Yemataw, Zerihun, Muzemil, Sadik, Ambachew, Daniel, Tripathi, Leena, Tesfaye, Kassahun, Chala, Alemayheu, Farbos, Audrey, O'Neill, Paul, Moore, Karen, Grant, Murray R., Studholme, David J., 2018. Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, pp. 285-293
- Penfold, Christopher A., Sybirna, Anastasiya, Reid, John E., Huang, Yun, Wernisch, Lorenz, Ghahramani, Zoubin, Grant, Murray R., Surani, M. Azim, 2018. Branch-recombinant Gaussian processes for analysis of perturbations in biological time series. Bioinformatics, 34 (17), pp. i1005-i1013
- Srivastava, Anjil Kumar, Orosa, Beatriz, Singh, Prashant, Cummins, Ian, Walsh, Charlotte, Zhang, Cunjin, Grant, Murray R., Roberts, Michael R., Anand, Ganesh Srinivasan, Fitches, Elaine, Sadanandom, Ari, 2018. SUMO suppresses the activity of the jasmonic acid receptor CORONATINE INSENSITIVE1. The Plant Cell, 30 (9), pp. 2099-2115
- Sambles, Christine, Salmon, Deborah L., Florance, Hannah, Howard, Thomas P., Smirnoff, Nicholas, Nielsen, Lene R., McKinney, Lea V., Kjær, Erik D., Buggs, Richard J. A., Studholme, David J., Grant, Murray R., 2017. Ash leaf metabolomes reveal differences between trees tolerant and susceptible to ash dieback disease. Scientific Data, 4
- Turner, Judith, O'Neill, Paul, Grant, Murray, Mumford, R., Thwaites, Richard, Studholme, David J., 2017. Genome sequences of 12 isolates of the EU1 lineage of Phytophthora ramorum, a fungus-like pathogen that causes extensive damage and mortality to a wide range of trees and other plants. Genomics Data, 12, pp. 17-21
- Yemataw, Zerihun, Chala, Alemayehu, Ambachew, Daniel, Studholme, David J., Grant, Murray R., Tesfaye, Kassahun, 2017. Morphological variation and inter-relationships of quantitative traits in enset (Ensete ventricosum (welw.) Cheesman) germplasm from South and South-Western Ethiopia. Plants, 6 (4)
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Sollars, Elizabeth S. A., Harper, Andrea L., Kelly, Laura J., Sambles, Christine M., Ramirez-Gonzalez, Ricardo H., Swarbreck, David, Kaithakottil, Gemy, Cooper, Endymion D., Uauy, Cristobal, Havlickova, Lenka, Worswick, Gemma, Studholme, David J., Zohren, Jasmin, Salmon, Deborah L., Clavijo, Bernardo J., Li, Yi, He, Zhesi, Fellgett, Alison, McKinney, Lea Vig, Nielsen, Lene Rostgaard et al (Select to open full list), 2017. Genome sequence and genetic diversity of European ash trees. Nature, 541, pp. 212-216
- Thatcher, Louise F., Cevik, Volkan, Grant, Murray R., Zhai, Bing, Jones, Jonathan D. G., Manners, John M., Kazan, Kemal, 2016. Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum. Journal of Experimental Botany, 67 (8), pp. 2367-2386
- Studholme, David J., McDougal, R. L., Sambles, Christine, Hansen, Everett, Hardy, Giles, Grant, Murray R., Ganley, R. J., Williams, N. M., 2016. Genome sequences of six Phytophthora species associated with forests in New Zealand. Genomics Data, 7, pp. 54-56
- Torres Zabala, Marta de, Zhai, Bing, Jayaraman, Siddharth, Eleftheriadou, Garoufalia, Winsbury, Rebecca, Yang, Ron, Truman, William, Tang, Saijung, Smirnoff, N., Grant, Murray R., 2016. Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection. New Phytologist, 209 (3), pp. 1120-1134
- Bailey, Mark, Srivastava, Anjil, Conti, Lucio, Nelis, Stuart, Zhang, Cunjin, Florance, Hannah, Love, Andrew, Milner, Joel, Napier, R. (Richard), Grant, Murray R., Sadanandom, Ari, 2016. Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana. Journal of Experimental Botany, 67 (1), pp. 353-363
- Shaw, Sophie, Le Cocq, Kate, Paszkiewicz, Konrad, Moore, Karen, Winsbury, Rebecca, de Torres Zabala, Marta, Studholme, David, Salmon, Deborah, Thornton, Christopher R., Grant, Murray R., 2016. Transcriptional reprogramming underpins enhanced plant growth promotion by the biocontrol fungus Trichoderma hamatum GD12 during antagonistic interactions with Sclerotinia sclerotiorumin soil. Molecular Plant Pathology, 17 (9), pp. 1425-1441
- Yang, Jing, Penfold, Christopher A., Grant, Murray R., Rattray, Magnus, 2016. Inferring the perturbation time from biological time course data. Bioinformatics, 32 (19), pp. 2956-2964
- Hodgetts, J., Karamura, G., Johnson, G., Hall, J., Perkins, K., Beed, F., Nakato, V., Grant, Murray, Studholme, David J., Boonham, N., Smith, J., 2015. Development of a lateral flow device for in-field detection and evaluation of PCR-based diagnostic methods forXanthomonas campestrispv.musacearum, the causal agent of banana xanthomonas wilt. Plant Pathology, 64 (3), pp. 559-567
- Sambles, Christine, Schlenzig, Alexandra, O'Neill, Paul, Grant, Murray, Studholme, David J., 2015. Draft genome sequences of Phytophthora kernoviae and Phytophthora ramorum lineage EU2 from Scotland. Genomics Data, 6, pp. 193-194
- Mata Saez, Lourdes de la, McCracken, Alistair R., Cooke, Louise R., O'Neill, Paul, Grant, Murray, Studholme, David J., 2015. Draft genome sequences of seven isolates of Phytophthora ramorum EU2 from Northern Ireland. Genomics Data, 6, pp. 191-192
- Hutt, Hugo, Everson, Richard, Grant, Murray, Love, John, Littlejohn, George, 2015. How clumpy is my image?. Soft Computing, 19 (6), pp. 1541-1552
- Ingle, Robert A., Stoker, Claire, Stone, Wendy, Adams, Nicolette, Smith, Rob, Grant, Murray, Carré, Isabelle, Roden, Laura C., Denby, Katherine J., 2015. Jasmonate signalling drives time-of-day differences in susceptibility of Arabidopsis to the fungal pathogen Botrytis cinerea. The Plant Journal, 84, pp. 937-948
- Li, Yaxiao, Scott, Rod, Doughty, James, Grant, Murray, Qi, Baoxiu, 2015. ProteinS-Acyltransferase 14 : a specific role for Palmitoylation in Leaf Senescence in Arabidopsis. Plant Physiology, 170 (1), pp. 415-428
- Hodgetts, J., Hall, J., Karamura, G., Grant, Murray, Studholme, David J., Boonham, N., Karamura, E., Smith, J. J., 2015. Rapid, specific, simple, in-field detection ofXanthomonas campestrispathovarmusacearumby loop-mediated isothermal amplification. Journal of Applied Microbiology, 119 (6), pp. 1651-1658
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Lewis, Laura, Polanskia, Krzysztof, de Torres-Zabala, Marta, Jayaraman, Siddharth, Bowden, Laura, Moore, Jonathan D., Penfold, Christopher A., Jenkins, Dafyd J., Hills, Claire E., Baxter, Laura, Kulasekaran, Satish, Truman, William, Littlejohn, George, Prusinska, Justyna, Mead, Andrew, Steinbrenner, Jens, Hickman, Richard J., Rand, D. A., Wild, David L., Ott, Sascha et al (Select to open full list), 2015. Transcriptional dynamics driving MAMP-triggered immunity and pathogen effector-mediated immunosuppression in Arabidopsis leaves following infection with pseudomonas syringae pv tomato DC3000. The Plant Cell, 27 (11), pp. 3038-3064
- de Torres Zabala, Marta, Littlejohn, George, Jayaraman, Siddharth, Studholme, David, Bailey, Trevor, Lawson, Tracy, Tillich, Michael, Licht, Dirk, Bölter, Bettina, Delfino, Laura, Truman, William, Mansfield, John, Smirnoff, Nicholas, Grant, Murray, 2015. Chloroplasts play a central role in plant defence and are targeted by pathogen effectors. Nature Plants, 1 (6)
- Littlejohn, George R., Mansfield, Jessica C., Christmas, Jacqueline T., Witterick, Eleanor, Fricker, Mark D., Grant, Murray, Smirnoff, N., Everson, Richard, Moger, Julian, Love, John, 2014. An update : improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology. Frontiers in Plant Science, 5, pp. 1-8
- Jensen, Michael Krogh, Lindemose, Søren, de Masi, Federico, Reimer, Julia J., Nielsen, Michael, Perera, Venura, Workman, Chris T., Turck, Franziska, Grant, Murray, Mundy, John, Petersen, Morten, Skriver, Karen, 2013. ATAF1 transcription factor directly regulates abscisic acid biosynthetic geneNCED3 in Arabidopsis thaliana. FEBS Open Bio, 3 (1), pp. 321-327
- Grant, Murray, Kazan, Kemal, Manners, John M., 2013. Exploiting pathogens' tricks of the trade for engineering of plant disease resistance : challenges and opportunities. Microbial Biotechnology, 6 (3), pp. 212-222
- Finiti, I., Leyva, M. O., López-Cruz, J., Calderan Rodrigues, B., Vicedo, B., Angulo, C., Bennett, A. B., Grant, Murray, García-Agustín, P., González-Bosch, C., Elzenga, T., 2013. Functional analysis of endo-1,4-ß-glucanases in response to Botrytis cinerea and Pseudomonas syringae reveals their involvement in plant-pathogen interactions. Plant Biology, 15 (5), pp. 819-831
- Perkins, L. E., Cribb, B. W., Brewer, P. B., Hanan, J., Grant, Murray, de Torres, M., Zalucki, M. P., 2013. Generalist insects behave in a jasmonate-dependent manner on their host plants, leaving induced areas quickly and staying longer on distant parts. Proceedings of the Royal Society B: Biological Sciences, 280 (1756)
- Quinn, Lisa, O'Neill, Paul A., Harrison, James, Paskiewicz, Konrad H., McCracken, Alistair R., Cooke, Louise R., Grant, Murray, Studholme, David J., 2013. Genome-wide sequencing of Phytophthora lateralis reveals genetic variation among isolates from Lawson cypress (Chamaecyparis lawsoniana) in Northern Ireland. FEMS Microbiology Letters, 344 (2), pp. 179-185
- Studholme, David J., Harris, Beverley, Le Cocq, Kate, Winsbury, Rebecca, Perera, Venura, Ryder, Lauren, Ward, Jane L., Beale, Michael H., Thornton, Chris R., Grant, Murray, 2013. Investigating the beneficial traits of Trichoderma hamatum GD12 for sustainable agriculture : insights from genomics. Frontiers in Plant Science, 4, pp. 1-13
- Chen, Yan-Jun, Perera, Venura, Christiansen, Michael W., Holme, Inger B., Gregersen, Per L., Grant, Murray, Collinge, David B., Lyngkjær, Michael F., 2013. The barley HvNAC6 transcription factor affects ABA accumulation and promotes basal resistance against powdery mildew. Plant Molecular Biology, 83 (6), pp. 577-590
- Perera, Venura, De Torres Zabala, Marta, Florance, Hannah, Smirnoff, Nicholas, Yang, Zheng Rong, Grant, Murray, 2012. Aligning extracted LC-MS peak lists via density maximization. Metabolomics, 8 (S1), pp. 175-185
- Yang, Zheng Rong, Grant, Murray, 2012. An ultra-fast metabolite prediction algorithm. PLoS One, 7 (6), pp. 1-11
- Newbigin, Edward, Rayson, Samantha, Arciga-Reyes, Luis, Wootton, Lucie, Torres Zabala, Marta de, Truman, William, Graham, Neil, Davies, Brendan, Grant, Murray, 2012. A role for nonsense-mediated mRNA decay in plants : pathogen responses are induced in Arabidopsis thaliana NMD mutants. PLoS One, 7 (2), pp. 1-13
- Sanchez-Vallet, A., Lopez, G., Ramos, B., Delgado-Cerezo, M., Riviere, M. -P., Llorente, F., Fernandez, P. V., Miedes, E., Estevez, J. M., Grant, Murray, Molina, A., 2012. Disruption of abscisic acid signaling constitutively activates arabidopsis resistance to the necrotrophic fungus plectosphaerella cucumerina. Plant Physiology, 160 (4), pp. 2109-2124
- Wasukira, Arthur, Tayebwa, Johnbosco, Thwaites, Richard, Paszkiewicz, Konrad, Aritua, Valente, Kubiriba, Jerome, Smith, Julian, Grant, Murray, Studholme, David J., 2012. Genome-wide sequencing reveals two major sub-lineages in the genetically monomorphic pathogen xanthomonas campestris pathovar musacearum. Genes, 3 (4), pp. 361-377
- Rose, Laura E., Atwell, Susanna, Grant, Murray, Holub, E. B., 2012. Parallel loss-of-function at the RPM1 bacterial resistance locus in Arabidopsis thaliana. Frontiers in Plant Science, 3
- Rayson, Samantha, Ashworth, Mary, Torres Zabala, Marta de, Grant, Murray, Davies, Brendan, 2012. The salicylic acid dependent and independent effects of NMD in plants. Plant Signaling & Behavior, 7 (11), pp. 1434-1437
- Studholme, David J., Wasukira, Arthur, Paszkiewicz, Konrad, Aritua, Valente, Thwaites, Richard, Smith, Julian, Grant, Murray, 2011. Draft genome sequences of xanthomonas sacchari and two banana-associated xanthomonads reveal insights into the xanthomonas group 1 clade. Genes, 2 (4), pp. 1050-1065
- Robert-Seilaniantz, Alexandre, Jones, Jonathan D. G., Grant, Murray, 2011. Hormone crosstalk in plant disease and defense : more than just JASMONATE-SALICYLATE antagonism. Annual Review of Phytopathology, 49 (1), pp. 317-343
- Truman, W. M., Bennett, M. H., Turnbull, C. G. N., Grant, Murray, 2010. Arabidopsis auxin mutants are compromised in systemic acquired resistance and exhibit aberrant accumulation of various indolic compounds. Plant Physiology, 152 (3), pp. 1562-1573
- Forsyth, Alec, Mansfield, John W., Grabov, Nina, de Torres, Marta, Sinapidou, Eva, Grant, Murray, 2010. Genetic dissection of basal resistance to pseudomonas syringaepv.phaseolicolain accessions of Arabidopsis. Molecular Plant-Microbe Interactions, 23 (12), pp. 1545-1552
- Studholme, David J., Kemen, Eric, MacLean, Daniel, Schornack, Sebastian, Aritua, Valente, Thwaites, Richard, Smith, Julian, Jones, Jonathan D.G., Grant, Murray, 2010. Genome-wide sequencing data reveals virulence factors implicated in banana Xanthomonas wilt. FEMS Microbiology Letters, 310 (2), pp. 182-192
- Forcat, Silvia, Bennett, Mark, Mansfield, John W., Grant, Murray, 2010. Rapid linkage of indole carboxylic acid to the plant cell wall identified as a component of basal defence in Arabidopsis against hrp mutant bacteria. Phytochemistry, 71 (8-9), pp. 870-876
- Ward, Jane L., Forcat, Silvia, Beckmann, Manfred, Bennett, Mark, Miller, Sonia J., Baker, John M., Hawkins, Nathaniel D., Vermeer, Cornelia P., Lu, Chuan, Lin, Wanchang, Truman, William M., Beale, Michael H., Draper, John, Mansfield, John W., Grant, Murray, 2010. The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. The Plant Journal, 63 (3), pp. 443-457
- de Torres Zabala, Marta, Bennett, Mark H., Truman, William H., Grant, Murray, 2009. Antagonism between salicylic and abscisic acid reflects early host-pathogen conflict and moulds plant defence responses. The Plant Journal, 59 (3), pp. 375-386
- Grant, Murray, Jones, J. D. G., 2009. Hormone (dis)harmony moulds plant health and disease. Science, 324 (5928), pp. 750-752
- Kissen, Ralph, Pope, Tom W., Grant, Murray, Pickett, John A., Rossiter, John T., Powell, Glen, 2009. Modifying the Alkylglucosinolate profile in Arabidopsis thaliana alters the Tritrophic interaction with the Herbivore Brevicoryne brassicae and Parasitoid Diaeretiella rapae. Journal of Chemical Ecology, 35 (8), pp. 958-969
- Savage, Richard S., Heller, K. (Katherine), Xu, Yang, Ghahramani, Zoubin, Truman, William M., Grant, Murray, Denby, Katherine J., Wild, David L., 2009. R/BHC : fast Bayesian hierarchical clustering for microarray data. BMC Bioinformatics, 10
- Forcat, Silvia, Bennett, Mark H., Mansfield, John W., Grant, Murray, 2008. A rapid and robust method for simultaneously measuring changes in the phytohormones ABA, JA and SA in plants following biotic and abiotic stress. Plant Methods, 4 (1)
- Pope, Tom W., Kissen, Ralph, Grant, Murray, Pickett, John A., Rossiter, John T., Powell, Glen, 2008. Comparative innate responses of the aphid parasitoid diaeretiella rapae to Alkenyl Glucosinolate derived isothiocyanates, Nitriles, and Epithionitriles. Journal of Chemical Ecology, 34 (10), pp. 1302-1310
- Smirnoff, Nick, Grant, Murray, 2008. Plant Biology : do DELLAs do defence?. Current Biology, 18 (14), pp. R617-R619
- Jensen, Michael K., Hagedorn, Peter H., de Torres-Zabala, Marta, Grant, Murray, Rung, Jesper H., Collinge, David B., Lyngkjaer, Michael F., 2008. Transcriptional regulation by an NAC (NAM-ATAF1,2-CUC2) transcription factor attenuates ABA signalling for efficient basal defence towards Blumeria graminisf. sp.hordeiin Arabidopsis. The Plant Journal, 56 (6), pp. 867-880
- de Torres-Zabala, Marta, Truman, William, Bennett, Mark H, Lafforgue, Guillaume, Mansfield, John W, Rodriguez Egea, Pedro, Bögre, Laszlo, Grant, Murray, 2007. Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease. The EMBO Journal, 26 (5), pp. 1434-1443
- Loake, Gary, Grant, Murray, 2007. Salicylic acid in plant defence - the players and protagonists. Current Opinion in Plant Biology, 10 (5), pp. 466-472
- Jones, Alexandra M., Bennett, Mark H., Mansfield, John W., Grant, Murray, 2006. Analysis of the defence phosphoproteome of Arabidopsis thaliana using differential mass tagging. Proteomics, 6 (14), pp. 4155-4165
- Truman, William, Bennett, Mark H., Kubigsteltig, Ines, Turnbull, Colin, Grant, Murray, 2006. Arabidopsissystemic immunity uses conserved defense signaling pathways and is mediated by jasmonates. Proceedings of the National Academy of Sciences of the United States of America, 104 (3), pp. 1075-1080
- Jones, Alexandra M., Thomas, V., Bennett, M. H., Mansfield, J., Grant, Murray, 2006. Modifications to the Arabidopsis defense proteome occur prior to significant transcriptional change in response to inoculation with pseudomonas syringae. Plant Physiology, 142 (4), pp. 1603-1620
- Ashley, M. K., Grant, Murray, Grabov , A., 2006. Plant responses to potassium deficiencies : a role for potassium transport proteins. Journal of Experimental Botany, 57 (2), pp. 425-436
- de Torres, Marta, Mansfield, John W., Grabov, Nina, Brown, Ian R., Ammouneh, Hassan, Tsiamis, George, Forsyth, Alec, Robatzek, Silke, Boch, Jens, Grant, Murray, 2006. Pseudomonas syringae effector AvrPtoB suppresses basal defence in Arabidopsis. The Plant Journal, 47 (3), pp. 368-382
- Lamb, Chris, Grant, Murray, 2006. Systemic immunity. Current Opinion in Plant Biology, 9 (4), pp. 414-420
- Truman, William, Zabala, Marta Torres, Grant, Murray, 2006. Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance. The Plant Journal, 46 (1), pp. 14-33
- Bennett, Mark, Mehta, Monaz, Grant, Murray, 2005. Biophoton imaging : a nondestructive method for assaying RGene responses. Molecular Plant-Microbe Interactions, 18 (2), pp. 95-102
- Zabala, Marta de Torres, Bones, Atle M., Grant, Murray, Bennett, Richard, Lim, Yin Sze, Kissen, Ralph, Rossiter, John T., 2005. Characterisation of recombinant epithiospecifier protein and its over-expression in Arabidopsis thaliana. Phytochemistry, 66 (8), pp. 859-867
- Al-Daoude, A., Torres Zabala, Marta de, Ko , Jong-Hyun, Grant, Murray, 2005. RIN13 is a positive regulator of the plant disease resistance protein RPM1. The Plant Cell, 17 (3), pp. 1016-1028
- Jones, Alexandra M., Thomas, Vincent, Truman, Bill, Lilley, Kathryn, Mansfield, John, Grant, Murray, 2004. Specific changes in the Arabidopsis proteome in response to bacterial challenge : differentiating basal and R-gene mediated resistance. Phytochemistry, 65 (12), pp. 1805-1816
- Torres, Marta de, Sanchez, Pedro, Fernandez-Delmond, Isabelle, Grant, Murray, 2003. Expression profiling of the host response to bacterial infection : the transition from basal to induced defence responses inRPM1-mediated resistance. The Plant Journal, 33 (4), pp. 665-676
- Jones, Alexandra M, Grant, Murray, 2003. Finding the functional gems in plant genomes. Genome Biology, 4 (12)
- Holt, Ben F., Boyes, Douglas C., Ellerström, Mats, Siefers, Nicholas, Wiig, Aaron, Kauffman, Scott, Grant, Murray, Dangl, Jeffery L., 2002. An evolutionarily conserved mediator of plant disease resistance gene function is required for normal Arabidopsis development. Developmental Cell, 2 (6), pp. 807-817
- Sanchez, Pedro, de Torres Zabala, Marta, Grant, Murray, 2000. AtBI-1, a plant homologue of Bax Inhibitor-1, suppresses Bax-induced cell death in yeast and is rapidly upregulated during wounding and pathogen challenge. The Plant Journal, 21 (4), pp. 393-399
- Grant, Murray, Brown, Ian, Adams, Sally, Knight, Marc, Ainslie, Alastair, Mansfield, John, 2000. The RPM1 plant disease resistance gene facilitates a rapid and sustained increase in cytosolic calcium that is necessary for the oxidative burst and hypersensitive cell death. The Plant Journal, 23 (4), pp. 441-450
- Mansfield, John, Grant, Murray, 1999. Early events in host-pathogen interactions. Current Opinion in Plant Biology, 2 (4), pp. 312-319
- Grant, Murray, McDowell, J. M., Sharpe, A. G., de Torres Zabala, M., Lydiate, D. J., Dangl, J. L., 1998. Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 95 (26), pp. 15843-15848
- Godiard, Laurence, Grant, Murray, Dietrich, Robert A., Kiedrowski, Siegrid, Dangl, Jeffery L., 1994. Perception and response in plant disease resistance. Current Opinion in Genetics & Development, 4 (5), pp. 662-671
- Rice, Stephen J., Grant, Murray, Reynolds, Paul H. S., Farnden, Kevin J. F., 1993. DNA sequence of Nodulin-45 from Lupinus angustifolius. Plant Science, 90 (2), pp. 155-166
- Dickson, James M. J. J., Vincze, Eva, Grant, Murray, Smith, Laura A., Rodber, Karen A., Farnden, Kevin J. F., Reynolds, Paul H. S., 1992. Molecular cloning of the gene encoding developing seed l-asparaginase from Lupinus angustifolius. Plant Molecular Biology, 20 (2), pp. 333-336
- Lough, Tony J., Reddington, Brett D., Grant, Murray, Hill, Diana F., Reynolds, Paul H. S., Farnden, Kevin J. F., 1992. The isolation and characterisation of a cDNA clone encoding L-asparaginase from developing seeds of lupin (Lupinus arboreus). Plant Molecular Biology, 19 (3), pp. 391-399
- Grant, Murray, Carne, Alan, Hill, Diana F., Farnden, Kevin J. F., 1989. The isolation and characterization of a cDNA clone encoding Lupinus angustifolius root nodule glutamine synthetase. Plant Molecular Biology, 13 (5), pp. 481-490
- Rufián, José S., López-Márquez, Diego, López-Pagán, Nieves, Grant, Murray, Ruiz-Albert, Javier, Beuzón, Carmen R., 2017. Generating chromosome-located transcriptional fusions to fluorescent proteins for single-cell gene expression analysis in pseudomonas syringae. In Medina, C.; López-Baena , F. (eds.), Host-Pathogen Interactions, New York, NY, Humana Press, pp. 183-199
- Hutt, Hugo, Everson, Richard, Grant, Murray, Love, John, Littlejohn, George, 2013. How clumpy is my image? Evaluating crowdsourced annotation tasks. 13th UK Workshop on Computational Intelligence (UKCI), Guildford, 9-11 Sep 2013, Published in 2013 13th UK Workshop on Computational Intelligence (UKCI), pp. 136-143
| Title | Funder | Award start | Award end |
|---|---|---|---|
| Xanthomonas plant diseases: mitigating existing, emerging and future threats to UK agriculture | BBSRC | 01 Aug 2020 | 31 Jul 2023 |
| Co-ordination Team for the Bacterial Diseases of Plants Initiative | BBSRC | 01 May 2020 | 30 Apr 2023 |
| China Partnering Award: Does chloroplast reactive oxygen underpin plant disease resistance? | BBSRC | 01 Jul 2019 | 30 Jun 2022 |
| US Partnering Award: The role of the chloroplast in activation of systemic immunity | BBSRC | 01 Apr 2018 | 31 Mar 2022 |
| Towards engineering disease resistance in Banana to Fusarium Wilt - avoiding the next apocalypse | Royal Society | 01 Dec 2017 | 30 Nov 2021 |
| Ion mobility mass spectrometer for proteomics facility. ALERT19 | BBSRC | 01 Jul 2020 | 30 Jun 2021 |
| Understanding the mechanism of chloroplast immunity | BBSRC | 01 Jan 2017 | 31 May 2021 |
| CoA: Retaining the Ashes: The potential for ash populations to be restored following the dieback epidemic; linked to Ideate 56318 | UK Research and Innovation | 01 Nov 2020 | 31 May 2021 |
| Retaining the Ashes: The potential for ash populations to be restored following the dieback epidemic | BBSRC | 09 Aug 2018 | 07 Feb 2021 |
| Developing analytical methods to determine the role of NAD and ADP-ribosylation in plant defence and disease (Daniel Pap) Undergraduate Vacation Bursary | British Society for Plant Pathology | 27 Jul 2020 | 26 Sep 2020 |
| A role for 3 prime O beta ribofuranosyladenosine in altering plant immunity | Royal Society | 30 Nov 2018 | 25 Apr 2019 |
| (Susan Breen) Vacation studentship for Nicole Hargreaves:Investigating the role of the Chloroplast in Plant Immunity | British Society for Plant Pathology | 02 Jul 2018 | 01 Sep 2018 |
| 16ALERT: Mid-Range Equipment Initiative: A high sensitivity triple quadruple mass spectrometer coupled to an ultra-high pressure liquid chromatograph system for quantitative analysis | BBSRC | 01 Jul 2017 | 30 Jun 2018 |
| Towards protecting the UK landscape; a novel method to screen for resistance to ash dieback while mitigating herbivory tradeoffs | BBSRC | 01 Oct 2016 | 31 Mar 2018 |
| Re-engineering plant defenses to nullify phytopathogen virulence strategies | Leverhulme Trust | 25 Apr 2016 | 14 Sep 2017 |
| Vacation Studentship for Breagha Magill - The role of truncated R proteins in plant-pathogen interactions | British Society for Plant Pathology | 19 Jun 2017 | 18 Aug 2017 |
| Enhancing human health and food security through disease resistant, biofortified bananas | BBSRC | 15 Sep 2016 | 31 Dec 2016 |