Assistant Professor

Email:  

Phone: 024 765 73527

Office: D135

Twitter: @MojganRabiey

Research Clusters

Plant & Agricultural Biosciences (Cluster Co-Lead)

Environment & Ecology

Microbiology & Infectious Disease

Warwick Centres and GRPs

Warwick Crop Centre

Other Roles

Opportunities in the group

For PhD and postdoctoral opportunities, and interest in potential collaborations, please contact me at the above email address.

Research/Teaching Interests

Crops and trees are attacked by bacterial pathogens, causing huge economic losses. Current control measures for many of these diseases are limited and relatively ineffective. As we are facing a global rise in antibiotic resistance in bacterial plant diseases, there is an urgent need to develop novel measures to control pathogens of important crops. One promising strategy is using naturally occurring bacteriophages for treating plant bacterial diseases. Bacteriophages (phages) are viruses that, as opposed to antibiotics, only infect specific strains of bacteria, and in lab studies can significantly control bacterial populations.

In my lab we are developing phage therapy to treat bacterial diseases of trees and important crops. We also investigate the evolution of pathogenic bacteria and bacteriophages to understand the genetic mechanism of bacteriophage-bacteria interaction, and how bacteriophages can be utilised as an alternative to antibiotics to control bacterial diseases in plants.

Research: Technical Summary

There is a critical need to develop new pathogen control methods in crop production that do not require antibiotics. Research in my group is focused on the development of phage therapy to treat bacterial pathogens that are otherwise difficult to treat. We isolate bacteriophages from plant and soil environment and fully characterise them using genome sequencing, transmission electron microscopy and in vitro assays. The efficacy of phages to reduce the bacterial population are tested on the plant environment.

We perform detailed characterisation of phage-bacteria-plant interaction by genetic engineering and fluorescent labelling of phages and bacteria to fully monitor their movement within plant tissues by confocal microscopy.

We also investigate the genetic mechanism of phage-bacteria interaction by passaging and coevolutionary experiments in vitro and in planta. This is to develop strategies to prevent bacterial resistance emerging and to show the specific resistance mechanisms that are likely to emerge, informing resistance management and the development of tree and crop protection measures in the future