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Publications

2023

"Supramolecular organization and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane", Brown CM, Corey RA, Gerald A, Gao Y, Choi YK, Luna E, Gilleron M, Destainville N, Nigou J, Loquet A, Fullam E, Im W, Stansfeld PJ, Chavent M, PNAS 2023 120 (5) link to the paper Link opens in a new window

2022

"Interrogation of the Pathogen Box reveals small molecule ligands against the mycobacterial trehalose transporter LpqY-SugABC", Radhakrishnan A, Brown CM, Guy CS, Cooper CMV, Stansfeld P, Fullam E, RSC Med Chem 2022 13 1225 Emerging Investigator Issue link to the paperLink opens in a new window

"Imaging of anti-tubercular multimeric boronic acids at the cell surface by click-probe capture" Guy CS, Tomas R, Gibson MI, F Fullam, Chem Commun 2022 58, 9361 Pioneering Investigator Issue link to the paperLink opens in a new window

2021

"Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC" Karlikowska M, Singh A, Bhatt A, Ott S, Bottrill AR, Besra GS, Fullam E  The Cell Surface 2021 7 100053 link to the paperLink opens in a new window

"Osmium–arene complexes with high potency towards Mycobacterium tuberculosis" Coverdale JPC, Guy CS, Bridgewater, Needham RJ, Fullam E, Sadler PJ, Metallomics 2021 13 mfab007 link to the paperLink opens in a new window

"‘Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter" Furze CM, Delso I, Casal E, Guy CS, Seddon C, Brown Cm, Parker HL, Radhakrishnan A, Pacheco-Gomez R, Stansfeld PJ, Angulo J, Cameron AD, Fullam E, J. Biol. Chem. 2021 296 100307 link to the paperLink opens in a new window

"Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?" Fullam E, Young RJ RSC Med Chem (2021) 12 43-56 (2021) 12 43 link to the paperLink opens in a new window

2020

"Asymmetric trehalose analogues to probe disaccharide processing pathways in mycobacteria" Parker HL, Tomas RMF, Furze CM, Guy CS, Fullam E, Org Biomol Chem 2020 18 3607 Glycosylation: new methodologies and applications themed issue link to the paperLink opens in a new window

2019

 ‘Dimeric benzoboroxoles for targeted activity against Mycobacterium tuberculosis’ Guy CS, Murray K, Gibson MI, Fullam E, Org. Biomol. Chem. 2019 17, 9524 link to the paperLink opens in a new window

Structural basis of glycerophosphodiester recognition by the Mycobacterium tuberculosis substrate-binding protein UgpB’ Fenn JS, Nepravishta R, Guy CS, Harrison J, Angulo J, Cameron AD, Fullam E, ACS Chemical Biology 2019 14 1879 link to the paperLink opens in a new window

“Targeting extracellular glycans: Tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosisGuy CS, Gibson MI, Fullam E, Chem. Sci. 2019 10 5935 link to the paperLink opens in a new window

2018

“A GFP-strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatisRadhakrishnan A, Furze CM, Ahangar MS, Fullam E RSC Advances 2018 8 33087 link to the paperLink opens in a new window

Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase, NagA, enzyme” Ahangar MS, Furze CM, Guy CS, Cooper C, Maskew KS, Graham B, Cameron AD, Fullam E J. Biol Chem. 2018 293 9770 link to the paperLink opens in a new window

“Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms” Richards SJ, Isufi K, Wilkins LE, Lipecki J, Fullam E, Gibson MI. Biomacromolecules 2018 19 256 link to the paperLink opens in a new window