Biomedical Sciences
Our research programme in Translational and Experimental Medicine integrates laboratory-based biologists, chemists, engineers and clinicians with computer-based mathematicians, statisticians and data analysts to exploit knowledge derived from fundamental discovery science to develop novel or innovative drugs, devices, techniques and treatments and to provide public health advice for improving the clinical outcomes for patients. The work of the unit is particularly focused on reproductive medicine, metabolic disease and on novel cancer therapy and delivery systems.
Biomedical Sciences News
Wellcome Bioimaging Award - A Multi-modal Imaging Platform Using Light-Sheet and Photostable Probes for Quantitative Cell and Tissue-Scale Biology
Satyajit Mayor, Mohan Balasubramanian and Masanori Mishima along with a group in the USA (Abhishek Kumar at Marine Biological laboratories- MBL- WoodsHole) have been awarded a Wellcome Trust Bioimaging Award.
In Phase 1 of this project, feasibility, proof-of-principle, and ease of use of the prototype light-sheet system with three detection modalities using existing and new fluorescent proteins will be established. In Phase 2, we explore a breadth of biological questions through investigation of model membranes, cultured cells (yeast, mammalian), and animal models (nematode, fly, fish). Our ultimate goal is to develop transformative imaging technology including optics and probes for widespread use by quantitative cell biologists everywhere.
EnteroBase in 2025: exploring the genomic epidemiology of bacterial pathogens
A temperature-induced metabolic shift in the emerging human pathogen Photorhabdus asymbiotica
Dr Erin Greaves explains her lab's research into endometriosis and how she hopes her work could help millions of women worldwide.