Biomedical Sciences
Our research programme in Translational and Experimental Medicine integrates laboratory-based biologists, chemists, engineers and clinicians with computer-based mathematicians, statisticians and data analysts to exploit knowledge derived from fundamental discovery science to develop novel or innovative drugs, devices, techniques and treatments and to provide public health advice for improving the clinical outcomes for patients. The work of the unit is particularly focused on reproductive medicine, metabolic disease and on novel cancer therapy and delivery systems.
Biomedical Sciences News
ATP-controlled remodeling in reconstituted actomyosin
This work was conducted by Sedigheh (Mobi) Ghanbarzadeh and Darius Koester in close collaboration with collaboration with theorists Sami Al-Izzi and Richard Morris from the School of Physics, UNSW Sydney (both alumni of Warwick) and discusses how different levels of ATP (our loved fuel for molecular motors and other cellular processes) can lead to different dynamics and patterns of force generation by membrane tethered actomyosin networks. Inspired by experimental observations, we developed a new way of using a hydrodynamics approach to describe a hierarchical system of membrane tethered actin networks with a layer of force generating myosin motors atop that interact with each other while taking into account how myosin motor activity and affinity to actin depends on ATP concentrations. Read the paper here.Link opens in a new window
Safety and efficacy of a temperature-controlled ablation system for ventricular tachycardia: Results from the TRAC-VT study
The eduWOSM: a benchtop advanced microscope for education and research
Dr Erin Greaves explains her lab's research into endometriosis and how she hopes her work could help millions of women worldwide.