Latest Publications
Effects of next-generation, dual-active-ingredient, long-lasting insecticidal net deployment on insecticide resistance in malaria vectors in Tanzania: an analysis of a 3-year, cluster-randomised controlled trial
Louisa A Messenger, Nancy S Matowo, Chad L Cross, Mohamed Jumanne, Natalie M Portwood, Jackline Martin, Eliud Lukole, Elizabeth Mallya, Jacklin F Mosha, Robert Kaaya, Oliva Moshi, Bethanie Pelloquin, Katherine Fullerton, Alphaxard Manjurano, Franklin W Mosha, Thomas Walker, Mark Rowland, Manisha A Kulkarni, Natacha Protopopof
Insecticide resistance among malaria-vector species is a pervasive problem that might jeopardise global disease-control efforts. Novel vector-control tools with different modes of action, including long-lasting insecticidal nets (LLINs) incorporating new active ingredients, are urgently needed to delay the evolution and spread of insecticide resistance. We aimed to measure phenotypic and genotypic insecticide-resistance profiles among wild Anopheles collected over 3 years to assess the longitudinal effects of dual-active-ingredient LLINs on insecticide resistance.