Chromatography and Metabolomics
Our chromatography and metabolomics facility offer a wide variety of separation and analysis options. A full work flow from compound concentration to quantification can be provided using the whole range of the equipment available; from preparative HPLC to GC or LC-MS.
Contact
Dr Sarah Bennett (SRL Manager)
Chris de Wolf (Chromatography Specialist)
School of Life Sciences, Gibbet Hill Road, University of Warwick, CV4 7AL
Access
Our technology facilities are open to internal and external users. For more information, such as access and charging, please click on the following links:
Instruments and Services
Agilent 1290/1260 HPLC
- Purification and preparative separation of organic compounds.
- Diode array detector (190 to 950 nm).
- Evaporative light-scattering detector
- Sample temperature control.
- Temperature-controlled fraction collection in either 8 ml or 10 ml vials.
Thermo Dionex ICS 5000 Ion Chromatography System
- Quantification of charged compounds.
- Anion & Cation separation.
- Eluent generation system
- Conductivity and electrochemical detector.
- Sample temperature control.
Monday-Wednesday only
Agilent 1260 Analytical HPLC
- Separation and Quantification or small organic metabolites.
- Autosampler for autonomous sample runs.
- dual-channel UV detector (190-600 nm).
- Compatible with a wide variety of analytical-scale columns.
Agilent 1260 HPLC
- Purification and preparative separation of organic compounds.
- Diode array detector (190 to 950 nm).
- Sample temperature control.
- Temperature-controlled fraction collection in either 5 ml or 45 ml vials.
Thermo Dionex ICS 5000 Ion Chromatography System
- Quantification of charged compounds.
- Anion & Cation separation.
- Eluent generation system
- Conductivity and electrochemical detector.
- Sample temperature control.
Monday-Wednesday only
Agilent GCMS
- Quantification and identification of volatile compounds (liquid or gas phase).
- Autosampler for autonomous sample runs.
- Compatible with a wide variety of columns.
- This instrument is not within the BioSRL.
Thermo/Bruker Impact II LCMS
- Metabolite and lipid identification.
- Low sample volume.
- can be integrated into work-flow with HPLC, IC or GC samples.
Genevac Ez-vac 2
- Centrifugal solvent evaporator.
- Supports 2 ml, 10 ml, 50 ml and 400 ml samples.
- Wide range of solvents accepted (except HCl and HF).
- Faster drying times using customised methods and UV lamp.
Services
- LC, MS, GC and IC Instrument Training.
- Column and solvent selection.
- Method development.
- Application support.
- Data analysis and report writing.
- Commercial sample analysis.