Molecular Interactions BioSRL
The Molecular Interactions Bio-Analytical Shared Resource Laboratory (BioSRL) is capable of investigating macromolecules and their biomolecular binding properties. We have two different instruments that use refractive index or fluorescence intensity to investigate biological interactions.
For help in deciding which instrument would be best for your experiment click here.
Contact
Lesley Ward (Technology specialist)
Dr Sarah Bennett (Head of BioSRLs)
School of Life Sciences, Gibbet Hill Road, University of Warwick, CV4 7AL
Access
Our technology facilities are open to internal and external users. For more information, such as access and charging, please click on the following links:
University of Warwick - Access
University of Warwick users - link to booking calendars
Instruments and Services
Biacore T200
- Surface plasmon resonance instrument
- Concentration requirements: 1pM to 2mM
- Temperature control from 4 to 45°C
- Biacore Insite software is available to use on the analysis computer in C029, for off instrument analysis.
Monolith NT.115
- MicroScale themophoresis instrument
- Nano Blue/Red detector channels
- Concentration requirements: 10-9- 10-3M
- Temperature control
FIDA Neo
- Flow Induced Dispersion Analysis
- 280nm, 480nm, 640nm detectors
- Laminar flow/Taylor curve/hydrodynamic radius calculations
- nL/uL requirements
- Absolute size, stickiness, viscosity, aggregation, PDB correlation, sample loss, polydispersity index, labelling quality
- More information on consumables and software
Other instruments on campus - Polymer Research Technology Platform:
Octet RED96 ForteBio
- Bio-layer interferometry instrument
QSense QCM-D instrument
Both are available to use at the Polymer RTPLink opens in a new window; please contact Dan Lester ( d.lester@warwick.ac.ukLink opens in a new window).