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Mechanochemistry of Molecular Motors and Cytoskeletal Filaments, a focused scientific meeting, 8-9 May 2026, University of Warwick

A focused scientific meeting on cytoskeletal filaments and molecular motors - the cellular machinery that drives cell division, cell migration and the motility and correct distribution of organelles. The programme will include inspiring keynotes from Joe Howard and Kristen Verhey, and provide many speaking opportunities for postdocs and students. Further, we will celebrate the career of Rob Cross and his contributions to kinesin and tubulin biophysics as he transitions into life as Emeritus Professor. The event will also be available via Livestream.

Thu 05 Feb 2026, 10:44 | Tags: BMS

Multiparametric Electrogram Feature Analysis for Ventricular Tachycardia Functional Extra-Stimulus Substrate Mapping

Defining the critical VT substrate has been a major focus of R&D teams globally. The importance of functional substrate identification has been reported by several world-renowned groups. However, as we move towards implementation, standardisation of functional extra-stimulus mapping is required. Our work just published in JACC Journals attempts to address this.

What are the important electrogram features that provide the greatest accuracy in defining the VT isthmus?

This international, multicentre study provides insights important to consider as we work towards automation of the approach.

Read the paper here.Link opens in a new window

Thu 05 Feb 2026, 10:39 | Tags: BMS BMS_newpub

Patient recruitment begins for major real-world digital weight management study

A new Warwick Medical School study evaluating W8Buddy, a digital specialist weight management service, has started patient recruitment, potentially offering a solution to improve access to obesity care across the NHS.

Find out more about how W8Buddy began in this BBC news clip

Mon 26 Jan 2026, 09:41 | Tags: news ITM

Highly Ranked Scholar - Dr Thomas Barber

Dr Thomas Barber has been recognised by ‘Scholar GPSLink opens in a new window’ as highly ranked scholar in field of obesity for the last 5 years, placed in the top 0.05% of all scholars in the specialty worldwide, and ranked number 37Link opens in a new window in the world.

 

Wed 14 Jan 2026, 12:23 | Tags: news BMS

ShapeSpaceExplorer: Analysis of morphological transitions in migrating cells using similarity-based shape space mapping

The paper describes the development of ShapeSpaceExplorer, an interactive software package that makes it easy to analyse cell morphology without any prior knowledge of relevant shape features and in particular enables tracking how cell shape changes dynamically. At the core of our software is a new and efficient method to measure the similarity of two shapes. Pairwise distances from all shapes in the dataset are used to position each shape in a low-dimensional map of shape space. The user can explore this shape space and visualise average shapes from any region of interest, partition shape space to analyse shape distributions from different experimental conditions or measure the speed of shape changes between two regions of shape space. We also show that shape dynamics information is sufficient to predict when migrating cells change direction.
Read the paper here.Link opens in a new window

Wed 14 Jan 2026, 11:49 | Tags: BMS BMS_newpub

University of Warwick launches spin-out VerIQ Limited, a new medtech clinical trials accelerator

The University of Warwick has announced the launch of a new spin-out company, VerIQ Limited, to transform how medical device and health technology clinical trials are designed, initiated and delivered across the UK.

Thu 08 Jan 2026, 09:27 | Tags: news ITM

Warwick Medical School launches new Community First Responder scheme

Warwick Medical School has officially launched its Community First Responder scheme, part of the wider regional scheme led by West Midlands Ambulance Service University NHS Foundation Trust.

Wed 10 Dec 2025, 09:24 | Tags: news

Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Actin is a highly abundant and key protein that forms long filaments inside cells, helping them maintain shape, move, and divide. This functional versatility arises from its ability to interact with a wide range of binding partners and via tight regulation. One important mechanism of regulation is post-translational modifications such as actin arginylation.

A new study from the labs of Professor Mohan Balasubramanian, Associate Professor Masanori Mishima, Professor Karuna Sampath and collaborators, Dr Sarah Heissler and Dr Krishna Chinthalapudi, in the Ohio State College of Medicine, published in the Journal of Cell Biology, further our understanding of how arginylated actin looks and interacts with a key actin interactor Myosin II. Importantly, they found that the acidic amino acids in the N-terminus of actin facilitate interactions with a set of basic amino acids in myosin, and that arginylation might sort actin into locations wherein contractility is minimized.

Read the paper here.Link opens in a new window
Tue 09 Dec 2025, 11:33 | Tags: BMS BMS_newpub

Patient-led learning day boosts rheumatology confidence for final year medics

Our final-year medical students had an invaluable opportunity to deepen their understanding of a wide range of rheumatology conditions recently through a direct patient interaction day of teaching.

Thu 04 Dec 2025, 10:06 | Tags: news

MB ChB student wins Royal College of Psychiatrists' 2025 Medical Student Essay Prize

Congratulations to MB ChB student Grace Fisher, who has been named joint winner of the 2025 Medical Student Essay Prize from the Royal College of Psychiatrists' Faculty of Perinatal Psychiatry.

Mon 17 Nov 2025, 09:06 | Tags: news

Dean of Warwick Medical School receives Lifetime Achievement Award

Congratulations to the Dean of Warwick Medical School, Professor Gavin Perkins, who has received the Resuscitation Science Lifetime Achievement Award from the American Heart Association. This prestigious award recognises Gavin’s significant contributions to resuscitation research, including leading major trials evaluating mechanical chest compression devices, adrenaline and intraosseous vascular access.

Mon 17 Nov 2025, 08:37 | Tags: news

Celebrating our Highly Cited Researchers at Warwick Medical School

Three Warwick Medical School academics have been named in Clarivate’s Highly Cited Researcher List 2025.

Wed 12 Nov 2025, 14:02 | Tags: news

StayRose: a photostable StayGold derivative red-shifted by genetic code expansion

StayRose: a photostable StayGold derivative red-shifted by genetic code expansion was published in the Journal of Biological Chemistry last week by a team of scientists from the groups of Mohan Balasubramanian (WMS), Masanori Mishima (WMS), Allister Crow (SLS), Falk Schneider (WMS), Abhishek Kumar (Marine Biological Laboratory) and Lijiang Song (Warwick Chemistry), funded by a collaborative Wellcome Trust bioimaging grant.

This work was led by first author Dr Will Smith, who completed his PhD as part of the MRC DTP.

The work presents a new fluorescent protein named StayRose, which is the first red version of the photobleaching-resistant green protein StayGold. These photostable proteins can be tagged to proteins of interest for microscopy and overcome the previous issue of fluorescence loss during prolonged imaging. StayRose contains an unnatural amino acid, 3-aminotyrosine, which underpins its red colour. Tests showed that StayRose maintains the extreme photostability of StayGold. The work presents a StayRose crystal structure, the first of a 3-aminotyrosine-incorporating fluorescent protein, and demonstrates use of StayRose in bacteria and zebrafish embryos.

Read the paper here.Link opens in a new window

Thu 30 Oct 2025, 11:48 | Tags: BMS BMS_newpub

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN-38 in Treatment of Colorectal Cancer Model

A recent publication in Advanced Healthcare Materials led by PhD student Sophie Hill is the result of a collaboration between Sébastien Perrier and Robert Dallmann. Together they show the potential of cyclic peptide-polymer conjugate nanotubes as powerful drug delivery vectors in a mammalian model of human disease.

The Perrier lab has already shown that these nanotubes are great drug delivery tools due to their propensity for dynamic self-assembly, high aspect ratio morphology and structural interchangeability, and demonstrated the shielding abilities of the polymeric corona of nanotubes to enhance pro-drug bond stabilities and modulate hydrolysis.

Here, they have used a hydrophobic core with multiple drug units attached to improve drug loading capacity and overall efficiency of the nanotube carriers. They show in vitro efficacy and in vivo pharmacokinetic and anti-tumour pharmacodynamics of these nanotubes in colorectal cancer models, comparing the potent topoisomerase inhibitor SN-38 with its clinically-used parent pro-drug irinotecan.

This work highlights the potential of SN-38 nanotubes as well-tolerated therapeutic option for colorectal cancer, with implications for future clinical translation and improved patient outcomes.

Read the paper here.Link opens in a new window

Thu 30 Oct 2025, 11:45 | Tags: BMS BMS_newpub

1 in 8 children survive cardiac arrest outside hospital in England, according to first national report

For the first time, the OHCAO team at University of Warwick have published national data for children who suffer an out-of-hospital cardiac arrest, underscoring urgent need for CPR training.

Thu 23 Oct 2025, 11:21 | Tags: news

New study highlights equity gap in accessing menopause care

Warwick Medical School research has explored how women experience menopause and access care within the NHS, focusing on inequalities shaped by ethnicity, socioeconomic status, and cultural norms.

Thu 23 Oct 2025, 10:25 | Tags: news

Prof Swaran Singh named in list of top 50 most influential BAME health leaders

Professor Swaran Singh has been named in Health Service Journal’s (HSJ) list of the top 50 most influential Black, Asian and Minority Ethnic people in English health and care.

Wed 22 Oct 2025, 14:42 | Tags: news

New Dual-Action Antimicrobial Polymers with Anti-Inflammatory Properties

A recent publication in the ACS journal Biomacromolecules by Sebastien Perrier and Robert Dallmann, in collaboration with Monash University and the CSIRO in Australia, reports a major step forward in the design of antimicrobial materials that not only fight infection but also reduce harmful inflammation.

Antimicrobial polymers, inspired by cationic host defence peptides (HDPs), are emerging as promising alternatives to antibiotics in the global battle against antimicrobial resistance. In this study, the researchers synthesized a library of 15 copolymers using RAFT polymerization and explored their ability to modulate immune responses in activated macrophages.

Two copolymers stood out, showing the ability to suppress the NF-κB pro-inflammatory pathway, scavenge reactive oxygen species, and reduce IL-6 cytokine production. Remarkably, one of these also demonstrated strong antimicrobial activity against Pseudomonas aeruginosa.

This dual antimicrobial and anti-inflammatory action opens new therapeutic avenues for materials that can combat bacterial infections while preventing excessive inflammation and sepsis at infection sites.

Read the paper here.Link opens in a new window

Fri 17 Oct 2025, 15:16 | Tags: BMS BMS_newpub

Warwick secures UKRI backing to help bring digital Endometrium Function Test from lab to clinic

Congratulations to our researchers Joanne Muter and Chow Seng Kong on receiving funding through UKRI's new Proof of Concept programme to develop the digital Endometrium Function Test.

Mon 29 Sept 2025, 09:59 | Tags: BMS ITM

Warwick secures Knowledge Transfer Partnership for AI assisted microscopy

University of Warwick researchers have secured a Knowledge Transfer Partnership with Intelligent Imaging Innovations (3i) to roll out a new AI-guided microscopy platform.

Mon 22 Sept 2025, 15:47 | Tags: news BMS

Warwick Medical School rises to 13th place in the Guardian University Guide 2026

Warwick Medical School has risen eight places to 13th in the Guardian University Guide 2026.

Thu 18 Sept 2025, 10:25 | Tags: news

Leda Mirbahai Appointed to QAA Writing Group

Dr Leda Mirbahai has been appointed as a member of the writing group for QAA’s UK Quality Code Advice and Guidance – Principle 11 (Teaching, Learning, and Assessment).

Leda will be contributing to the development of guidance on designing assessments that are fair, reliable, accessible, authentic, and inclusive, including exploring how providers can offer different assessment options to enhance accessibility and inclusion. Publication of the new guidance is expected by June 2026. This appointment recognises Leda’s sector-wide leadership in inclusive assessment design.

Mon 15 Sept 2025, 13:44 | Tags: BMS

Flying Lifesavers: Drones could soon respond to cardiac arrests

Researchers at the University of Warwick have teamed up with the Welsh Ambulance Services University NHS Trust and autonomous drone specialists SkyBound for a National Institute for Health and Care Research (NIHR) study to test the feasibility of drone-delivered AEDs.

Mon 08 Sept 2025, 12:05 | Tags: news ITM

CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues

A new paper from the Saunders lab introduces CellMet, an open-source toolkit that extracts 3D cell shape and topology metrics within dense tissue. Going beyond basic measures like volume and surface area, CellMet reveal detailed morphological features - such as twisting shape - and highlights how cells interact and organise themselves. From organoids to Drosophila embryos, CellMet provides a powerful framework to reveal hidden tissue architecture.

Read the paper.Link opens in a new window
CellMetLink opens in a new window

Thu 04 Sept 2025, 09:30 | Tags: BMS BMS_newpub

Live cell LaBeRling

A new paper from the Royle lab describes a method to label membrane contact sites in living cells on-demand. Laura Downie found that the Lamin B Receptor (LBR), which is usually on the nuclear envelope, can be used as a multi-purpose contact site highlighter. With a bit of engineering, LBR can label ER contacts with the plasma membrane, mitochondria, lysosomes, endosomes, lipid droplets and the Golgi! We found Golgi-ER contact sites persist in mitosis, a time when the Golgi is broken down but the contact sites remain intact! As a bonus track, the paper contains a method to segment mitochondria and ER from volume-EM data using machine learning, and find their contacts in 3D.

Read the paper here.

Mon 28 Jul 2025, 16:55 | Tags: BMS BMS_newpub

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