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Biological Inorganic Chemistry

Structure and Dynamics of Metal-binding Proteins

ResearcherID



smta_cov.jpgOur work is concerned with the coordination chemistry of diamagnetic metal ions such as zinc, copper(I), and cadmium in proteins. We are particularly interested in the molecular mechanisms that govern the movements of zinc within whole organisms and within individual cells.

We use NMR and other spectroscopic techniques to study the structure and reactions of metalloproteins. Other techniques that are indispensable in our work are Electrospray Mass Spectrometry and protein expression and purification.

Please use the links below to find out more about our research interests.


Metallothioneins: an overview

Bacterial Metallothioneins

Plant MTs

Histidines in metallothioneins

Metallothioneins from worms

Blood plasma proteins involved in zinc transport

Metalloproteomics

Group photo June 2018

The group in June 2018: Hormoz Parsapour (MChem), Luke Scott (MChem), Deogratias Ikemere (ASI MSc), Claudia Blindauer, Alevtina Mikhaylina (Ph.D.), Agnieszka Mierek-Adamska (Marie Curie-Sklodowska Fellow), James Coverdale (Leverhulme Trust PDRA) . Not in the picture: Qinyi Yang (ASI MSc).