Professor Richard Napier
Professor & Deputy Head of School (Operations)
Email: Richard.Napier@warwick.ac.uk
Phone: 024 765 75094
Office: B139
Napier webpage
Research Clusters
Plant & Agricultural Biosciences
Warwick Centres and GRPs
Vacancies and Opportunities
For PhD and postdoctoral opportunities, and interest in potential collaborations, please contact me at the above email address.
Research Interests
Our primary interest is in how the plant hormone auxin works because its actions are the foundations for most of the green plant world. As biochemists, we are fascinated by how specificity is conferred for auxin. Millions of similar, but different small organic molecules cause no reaction at all, whilst the natural hormone molecule (known as indole-3-acetic acid, IAA) fits into its binding pocket perfectly.
We purify members of the auxin receptor family of proteins in the lab and use these in experiments to measure binding using advanced instruments like Biacore SPR (surface plasmon resonance). We are interested in how and why different members of the receptor family show preferences for different auxin mimics and this is important in agriculture because synthetic auxins are vitally important selective herbicides.
The Napier group also has research interests in next generation plastics and agriculture. Principally, we are interested in nanoparticles and determining whether or not polymers with particular characteristics (size, charge etc) can pass into plants and how we may use this information to design nanoparticles to carry very specific payloads to benefit crop performance, or to design nanoparticles which are specifically excluded from plants.
A second interest is in the development of policies to promote fresh food (Fruit and vegetable) production in the UK. In 2023 we published "Growing British - a strategy paper for promoting fresh produce production in the UK". We are developing a knowledge exchange hub for the edible horticulture sector and helping drive the Warwick Agri-Tech initiative. Warwick Agri-Tech will combine world class facilities at Warwick Manufacturing Group (WMG), Warwick Crop Centre (WCC) and the High Value Manufacturing Catapult to spearhead the much needed acceleration of automation and robotics into horticulture, field crops and forestry.
Research: Technical Summary
My biochemistry work on plant proteins includes receptors and membrane transport proteins, which are expressed using recombinant baculoviruses in insect cell culture. After purification we prepare proteins for structural biology according to need, and we assay for activity with SPR Biacore technology. We also use other biophysical tehniques to assess ligand binding and determine molecular mechanisms, including MST and ITC, and collaborate to use CD and additional biophysical methods as necessary.
Policy work brings together my interest in agriculture with my career experiences of working at applied research institutes as well as at the University of Warwick. Warwick Crop Centre specialises in research to support the edible horticulture sector and our policy work aims to create a primary pont of contact and reference for a fragmented community. We are adopting AI technologies to help provide relevant information, working with local councils on developing a fresh food supply strategy and setting up a policy research unit.
Warwick Agri-Tech brings together the engineering expertise of WMG with the Crop Centre's expertise in applied agriculture to the challenges of developing automotive, robotics and supply chain solutions for companies, with those companies.
Professor, 2005, University of Warwick
Bieleszová, Kristýna, Hladík, Pavel, Kubala, Martin, Napier, Richard, Brunoni, Federica, Gelová, Zuzana, Fiedler, Lukáš, Kulich, Ivan, Strnad, Miroslav, Doležal, Karel, Novák, Ondřej, Friml, Jiří and Žukauskaitė, Asta (2024) New fluorescent auxin derivatives : anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation, 102 . pp. 589-602. doi:10.1007/s10725-023-01083-0 ISSN 0167-6903.
Zeng, Yinwei, Verstraeten, Inge, Trinh, Hoang Khai, Lardon, Robin, Schotte, Sebastien, Olatunji, Damilola, Heugebaert, Thomas, Stevens, Christian, Quareshy, Mussa, Napier, Richard, Nastasi, Sara Paola, Costa, Alex, De Rybel, Bert, Bellini, Catherine, Beeckman, Tom, Vanneste, Steffen and Geelen, Danny (2023) Chemical induction of hypocotyl rooting reveals extensive conservation of auxin signalling controlling lateral and adventitious root formation. New Phytologist, 240 (5). pp. 1883-1899. doi:10.1111/nph.19292 ISSN 0028-646X.
Ramans-Harborough, Sigurd, Kalverda, Arnout P. , Manfield, Iain W., Thompson, Gary S., Kieffer, Martin, Uzunova, Veselina, Quareshy, Mussa, Prusinska, Justyna M., Roychoudhry, Suruchi, Hayashi, Ken-ichiro, Napier, Richard, del Genio, Charo and Kepinski, Stefan (2023) Intrinsic disorder and conformational co-existence in auxin co-receptors. Proceedings of the National Academy of Sciences, 120 (40). e2221286120. doi:10.1073/pnas.2221286120 ISSN 0027-8424.
Joshi, Chitra and Napier, Richard (2023) PIN structures shed light on their mechanism of auxin efflux. Journal of Experimental Botany, 74 (15). pp. 4377-4383. doi:10.1093/jxb/erad185 ISSN 0022-0957.
El Houari, Ilias, Klíma, Petr, Baekelandt, Alexandra, Staswick, Paul E., Uzunova, Veselina, Del Genio, Charo I., Steenackers, Ward, Dobrev, Petre I., Filepová, Roberta, Novák, Ondrej, Napier, Richard, Petrášek, Jan, Inzé, Dirk, Boerjan, Wout and Vanholme, Bartel (2023) Non‐specific effects of the CINNAMATE‐4‐HYDROXYLASE inhibitor piperonylic acid. The Plant Journal, 115 (2). pp. 470-479. doi:10.1111/tpj.16237 ISSN 0960-7412.
Becker, Jonas, Terracciano, Roberto, Yilmaz, Gokhan, Napier, Richard and Becer, C. Remzi (2023) Step-growth glycopolymers with a defined tacticity for selective carbohydrate–lectin recognition. Biomacromolecules, 24 (4). pp. 1924-1933. doi:10.1021/acs.biomac.3c00133 ISSN 1525-7797.
Sinigaglia Angonese, Paula, Silva de Queiroz, Andrew Rerison, Sinigaglia Angonese, Liana, Mesquita Machado, Filipi, Napier, Richard, Markus, Catarine, Delatorre, Carla and Merotto, Aldo (2023) Rapid necrosis : implications of environmental conditions and plant growth stage on 2,4-D resistance and effect of other auxinic herbicides in Sumatran fleabane (Conyza sumatrensis). Weed Technology, 37 (2). pp. 174-184. doi:10.1017/wet.2023.21 ISSN 0890-037X.
Prusińska, Justyna, Uzunova, Veselina, Schmitzer, Paul, Weimer, Monte, Bell, Jared and Napier, Richard (2023) The differential binding and biological efficacy of auxin herbicides. Pest Management Science, 79 (4). pp. 1305-1315. doi:10.1002/ps.7294 ISSN 1526-498X.
Tungsirisurp, Sireethorn, O’Reilly, Rachel K. and Napier, Richard (2023) Nucleic acid aptamers as aptasensors for plant biology. Trends in Plant Science, 28 (3). pp. 359-371. doi:10.1016/j.tplants.2022.10.002 ISSN 1360-1385.
Parkinson, Sam J., Tungsirisurp, Sireethorn, Joshi, Chitra, Richmond, Bethany L., Gifford, Miriam L., Sikder, Amrita, Lynch, Iseult, O’Reilly, Rachel K. and Napier, Richard (2022) Polymer nanoparticles pass the plant interface. Nature Communications, 13 (1). 7385. doi:10.1038/s41467-022-35066-y ISSN 2041-1723.
Qi, Linlin, Kwiatowski, Mateusz, Chen, Huihuang, Howrmayer, Lukas, Sinclair, Scott, Zou, Minxia, del Genio, Charo I., Kubeš, Martin F., Napier, Richard, Jaworski, Krzysztof and Friml, Jiří (2022) Adenylate cyclase activity of TIR1/AFB auxin receptors in plants. Nature (611). pp. 133-138. doi:10.1038/s41586-022-05369-7 ISSN 0028-0836.
Zhao, Zerui, Liu, Xudong, Pan, Xukun, Napier, Richard, Dong, Liyao and Liu, Jun (2022) Different regulation of auxin homeostasis would be a possible mechanism conferring quinclorac resistance in Echinochloa crusgalli var. zelayensis. Weed Research, 62 (5). pp. 318-327. doi:10.1111/wre.12546 ISSN 0043-1737.
Fukui, Kosuke, Arai, Kazushi, Tanaka, Yuka, Aoi, Yuki, Kukshal, Vandna, Jez, Joseph M., Kubeš, Martin F., Napier, Richard, Zhao, Yunde, Kasahara, Hiroyuki and Hayashi, Ken-ichiro (2022) Chemical inhibition of auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis. Proceedings of the National Academy of Sciences, 119 (32). e2206869119. doi:10.1073/pnas.2206869119 ISSN 0027-8424.
Xu, Jiaqi, Liu, Xudong, Napier, Richard, Dong, Liyao and Li, Jun (2022) Mode of action of a novel synthetic auxin herbicide, halauxifen-methyl. Agronomy, 12 (7). 1659. doi:10.3390/agronomy12071659 ISSN 2073-4395.
de Figueiredo, Marcelo R. A., Küpper, Anita, Malone, Jenna M., Petrovic, Tijana, de Figueiredo, Ana Beatriz T. B., Campagnola, Grace, Peersen, Olve B., Prasad, Kasavajhala V.S.K., Patterson, Eric L., Reddy, Anireddy S.N., Kubeš, Martin F., Napier, Richard, Preston, Christopher and Gaines, Todd A. (2022) An in-frame deletion mutation in the degron tail of auxin co-receptor IAA2 confers resistance to the herbicide 2,4-D in Sisymbrium orientale. Proceedings of the National Academy of Sciences of the United States of America, 119 (9). e2105819119. doi:10.1073/pnas.2105819119 ISSN 0027-8424.
Figueiredo, Marcelo R. A. de, Küpper, Anita, Malone, Jenna M., Petrovic, Tijana, Figueiredo, Ana Beatriz T. B. de, Campagnola, Grace, Peersen, Olve B., Prasad, Kasavajhala V. S. K., Patterson, Eric L., Reddy, Anireddy S. N., Kubeš, Martin F., Napier, Richard, Dayan, Franck E., Preston, Christopher and Gaines, Todd A. (2022) An in-frame deletion mutation in the degron tail of auxin coreceptor IAA2 confers resistance to the herbicide 2,4-D in Sisymbrium orientale. Proceedings of the National Academy of Sciences of the United States of America, 119 (9). e2105819119. doi:10.1073/pnas.2105819119 ISSN 0027-8424.
Gooch, James, Tungsirisurp, Sireethorn, Costanzo, Hayley, Napier, Richard and Frascione, Nunzianda (2021) Generating aptamers towards human sperm cells using massively parallel sequencing. Analytical and Bioanalytical Chemistry, 413 . pp. 5821-5834. doi:10.1007/s00216-021-03562-7 ISSN 1618-2642.
Quan, Wen-Dong, Baker, Lewis A., Napier, Richard, O'Reilly, Rachel K., Stavros, Vasilios G., Staniforth, Michael and Wilks, Thomas R. (2021) Ultrafast spectroscopic investigation of discrete co-assemblies of a Zn-porphyrin–polymer conjugate with a hexapyridyl template. Chemical Physics Letters, 777 . 138736. doi:10.1016/j.cplett.2021.138736 ISSN 0009-2614.
el Houaria, I., van Beirsa, C., Artensa, H. E., Hanc, H., Chanoca, A., Opdenacker, D., Polliera, J., Sotrmea, V., Steenackers, W., Quareshy, M., Napier, R. (Richard), Beeckman, T., Frimic, J., de Rybela, B., Boerjan, W. and Vanholme, B. (2021) Seedling developmental defects upon blocking CINNAMATE 4-HYDROXYLASE are caused by perturbations in auxin 3 transport. New Phytologist, 230 (60). pp. 2275-2291. doi:10.1111/nph.17349 ISSN 0028-646X.
Napier, Richard (2021) The Story of Auxin-Binding Protein 1 (ABP1). Cold Spring Harbor Perspectives in Biology . a039909. doi:10.1101/cshperspect.a039909 ISSN 1943-0264.
Collis, Dominic W. P., Yilmaz, Gokhan, Yuan, Yichen, Monaco, Alessandra, Ohbaum, Guy, Shi, Yejiao, O'Malley, Clare, Uzunova, Veselina, Napier, Richard, Bitton, Ronit, Becer, Remzi and Azevedo, Helena S. (2021) Hyaluronan (HA)-inspired glycopolymers as molecular tools for studying HA functions. RSC Chemical Biology, 2 (2). pp. 568-576. doi:10.1039/D0CB00223B ISSN 2633-0679.
Pařízková, Barbora, Žukauskaitė, Asta, Vain, Thomas, Grones, Peter, Raggi, Sara, Kubeš, Martin F., Kieffer, Martin, Doyle, Siamsa M., Strnad, Miroslav, Kepinski, Stefan, Napier, Richard, Doležal, Karel, Robert, Stéphanie and Novák, Ondřej (2021) New fluorescent auxin probes visualize tissue-specific and subcellular distributions of auxin in Arabidopsis. New Phytologist, 230 (2). pp. 535-549. doi:10.1111/nph.17183 ISSN 0028-646X.
Sikder, Amrita, Pearce, Amanda K., Parkinson, Sam J., Napier, Richard and O’Reilly, Rachel K. (2021) Recent trends in advanced polymer materials in agriculture related applications. ACS Applied Polymer Materials, 3 (3). pp. 1203-1217. doi:10.1021/acsapm.0c00982 ISSN 2637-6105.
Todd, Olivia E., Figueiredo, Marcelo R. A., Morran, Sarah, Soni, Neeta, Preston, Christopher, Kubeš, Martin F., Napier, Richard and Gaines, Todd A. (2020) Synthetic auxin herbicides : finding the lock and key to weed resistance. Plant Science, 300 . 110631. doi:10.1016/j.plantsci.2020.110631 ISSN 0168-9452.
Monaco, Alessandra, Beyer, Valentin P., Napier, Richard and Becer, C. Remzi (2020) Multi-arm star shaped glycopolymers with precisely controlled core size and arm length. Biomacromolecules, 21 (9). pp. 3736-3744. doi:10.1021/acs.biomac.0c00838 ISSN 1525-7797.
Beyer, Valentin, Monaco, Alessandra, Napier, Richard, Yilmaz, Gokhan and Becer, C. Remzi (2020) Bottlebrush glycopolymers from 2-oxazolines and acrylamides for targeting DC-SIGN and MBL. Biomacromolecules, 21 (6). pp. 2298-2308. doi:10.1021/acs.biomac.0c00246 ISSN 1525-7797.
Oochi, Akihiro, Hajny, Jakub, Fukui, Kosuke, Nakao, Yukio, Gallei, Michelle, Quareshy, Mussa, Takahashi, Koji, Kinoshita, Toshinori, Ramans Harborough, Sigurd, Kepinski, Stefan, Kasahara, Hiroyuki, Napier, R. (Richard), Friml, Jiri and Hayashi, Ken-ichiro (2019) Pinstatic acid promotes auxin efflux transport by inhibiting PIN internalization. Plant Physiology, 180 (2). pp. 1152-1165. doi:10.1104/pp.19.00201 ISSN 0032-0889.
Kubes, Martin and Napier, Richard (2019) Non-canonical auxin signalling : fast and curious. Journal of Experimental Botany, 70 (10). pp. 2609-2614. doi:10.1093/jxb/erz111 ISSN 0022-0957.
Singh, Gaurav, Retzer, Katarzyna, Vosolsobě, Stanislav and Napier, R. (Richard) (2018) Advances in understanding the mechanism of action of the auxin permease AUX1. International Journal of Molecular Sciences, 19 (11). 3391. doi:10.3390/ijms19113391 ISSN 1422-0067.
Skalicky, V., Kubes, M., Napier, R. and Novak, O. (2018) Auxins and cytokinins : the role of subcellular organization on homeostasis. International Journal of Molecular Sciences, 19 (10). 3115. doi:10.3390/ijms19103115 ISSN 1422-0067.
Busi, Roberto, Goggin, Danica E., Heap, Ian, Horak, Michael J., Jugulam, Mithila, Masters, Robert A., Napier, R., Riar, Dilpreet S., Satchivi, Norbert M., Torra, Joel, Westra, Phillip and Wright, Terry R. (2018) Weed resistance to synthetic auxin herbicides. Pest Management Science , 74 (10). pp. 2265-2276. doi:10.1002/ps.4823 ISSN 1526-498X.
Quareshy, Mussa, Prusińska, Justyna, Kieffer, Martin, Fukui, Kosuke, Pardal , Alonso Javier, Lehmann, Silke, Schäfer, Patrick, Del Genio, Charo I., Kepinski, Stefan, Hayashi, Kenichiro, Marsh, Andrew and Napier, R. (Richard) (2018) The tetrazole analogue of the auxin indole-3-acetic acid binds preferentially to TIR1 and not AFB5. ACS Chemical Biology, 13 (9). pp. 2585-2594. doi:10.1021/acschembio.8b00527 ISSN 1554-8929.
Ishimaru, Yasuhiro, Hayashi, Ken-ichiro, Suzuki, Takeshi, Fukaki, Hidehiro, Prusińska, Justyna, Meesters, Christian, Quareshy, Mussa, Egoshi, Yuusuke, Matsuura, Hideyuki, Takahashi, Kosaku, Kato, Nobuki, Kombrink, Erich, Napier, R. (Richard), Hayashi, Kengo and Ueda, Minoru (2018) Jasmonic acid inhibits auxin-induced lateral rooting independently of the CORONATINE INSENSITIVE 1 receptor. Plant Physiology, 177 (4). pp. 1704-1716. doi:10.1104/pp.18.00357 ISSN 0032-0889.
Yilmaz, Gokhan, Uzunova, Veselina, Napier, R. (Richard) and Becer, C. Remzi (2018) Single-chain glycopolymer folding via host-guest interactions and its unprecedented effect on DC-SIGN binding. Biomacromolecules, 19 (7). pp. 3040-3047. doi:10.1021/acs.biomac.8b00600 ISSN 1526-4602.
Riemer, Martin, Uzunova, Veselina, Riemer, Nastja, Clarkson, Guy J., Pereira, Nicole, Napier, R. (Richard) and Shipman, Michael (2018) Phyllostictine A : total synthesis, structural verification and determination of substructure responsible for plant growth inhibition. Chemical Communications, 54 (52). pp. 7211-7214. doi:10.1039/c8cc03349h ISSN 1359-7345.
Retzer, Katarzyna, Singh, Gaurav and Napier, R. (Richard) (2018) It starts with TIRs. Nature Plants, 4 (7). pp. 410-411. ISSN 2055-026X doi:10.1038/s41477-018-0196-8
Gao, Yuan, Liu, Jun, Pan, Xukun, Liu, Dingrong, Napier, R. (Richard) and Dong, Liyao (2018) Quinclorac resistance induced by the suppression of the expression of 1-aminocyclopropane-1-carboxylic acid (ACC) synthase and ACC oxidase genes in Echinochloa crus-galli var. zelayensis. Pesticide Biochemistry and Physiology, 146 . pp. 25-32. doi:10.1016/j.pestbp.2018.02.005 ISSN 0048-3575.
Hoyerova, Klara, Hosek, Petr, Quareshy, Mussa, Li, Jun, Klima, Petr, Kubes, Martin, Yemm, Antony A., Neve, Paul, Tripathi, Ashutosh, Bennett , Malcolm J. and Napier, R. (Richard) (2018) Auxin molecular field maps define AUX1 selectivity : many auxin herbicides are not substrates. New Phytologist, 217 (4). pp. 1625-1639. doi:10.1111/nph.14950 ISSN 0028-646X.
Yilmaz, Gokhan, Uzunova, Veselina, Hartweg, Manuel, Beyer, Valentin, Napier, R. (Richard) and Becer, C. Remzi (2018) The effect of linker length on ConA and DC-SIGN binding of S-glucosyl functionalized poly(2-oxazoline)s. Polymer Chemistry, 9 (5). 611-618 . doi:10.1039/C7PY01939D ISSN 1759-9954.
Retzer, Katarzyna, Lacek, Jozef, Skokan, Roman, Del Genio, Charo I., Vosolsobě, Stanislav, Laňková, Martina, Malínská, Kateřina, Konstantinova, Nataliia, Zažímalová, Eva, Napier, R. (Richard), Petrášek, Jan and Luschnig, Christian (2017) Evolutionary conserved cysteines function as cis-acting regulators of Arabidopsis PIN-FORMED 2 distribution. International Journal of Molecular Sciences, 18 (11). 2274. doi:10.3390/ijms18112274 ISSN 1422-0067.
Quareshy, Mussa, Prusińska, Justyna, Li, Jun and Napier, R. (Richard) (2017) A cheminformatics review of auxins as herbicides. Journal of Experimental Botany . doi:10.1093/jxb/erx258 ISSN 0022-0957.
Novák, Ondřej, Napier, R. (Richard) and Ljung, Karin (2017) Zooming in on plant hormone analysis : tissue- and cell-specific approaches. Annual Review of Plant Biology, 68 (1). 1543-5008. doi:10.1146/annurev-arplant-042916-040812 ISSN 1543-5008.
Lavilla, Cristina, Yilmaz, Gokhan, Uzunova, Veselina, Napier, Richard, Becer, C. Remzi and Heise, Andreas (2017) Block sequence-specific glycopolypeptides with selective lectin binding properties. Biomacromolecules . doi:10.1021/acs.biomac.7b00356 ISSN 1525-7797.
Zhu, Ziqiang and Napier, R. (Richard) (2017) Jasmonate – a blooming decade. Journal of Experimental Botany, 68 (6). pp. 1299-1302. doi:10.1093/jxb/erx068 ISSN 1460-2431.
Steenackers, Ward Jan, Klíma, Petr, Quareshy, Mussa, Cesarino, Igor, Kumpf, Robert P., Corneillie, Sander, Araújo, Pedro, Viaene, Tom, Goeminne, Geert, Nowack, Moritz K, Ljung, Karin, Friml, Jiří, Blakeslee, Joshua J, Novák, Ondřej, Zažímalová, Eva, Napier, R. (Richard), Boerjan, Wout A and Vanholme, Bartel (2016) cis-cinnamic acid is a novel, natural auxin efflux inhibitor that promotes lateral root formation. Plant Physiology, 173 (1). pp. 552-565. doi:10.1104/pp.16.00943 ISSN 0032-0889.
Uzunova, Veselina V., Quareshy, Mussa, Del Genio, Charo I. and Napier, R. (Richard) (2016) Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity. Open Biology, 6 (10). 160139. doi:10.1098/rsob.160139 ISSN 2046-2441.
Steenackers, Ward Jan, Cesarino, Igor, Klíma, Petr, Quareshy, Mussa, Vanholme, Ruben, Corneillie, Sander, Kumpf, Robert P., Van de Wouwer, Dorien, Ljung, Karin, Goeminne, Geert, Novak, Ondrej, Zažímalová, Eva, Napier, R. (Richard), Boerjan, Wout A. and Vanholme, Bartel (2016) The allelochemical MDCA inhibits lignification and affects auxin homeostasis. Plant Physiology, 172 (2). pp. 874-888. doi:10.1104/pp.15.01972 ISSN 0032-0889.
Badescu, George O., Marsh, Andrew, Smith, Timothy R., Thompson, Andrew J. and Napier, R. (Richard) (2016) Kinetic characterisation of a single chain antibody against the Hormone Abscisic Acid : comparison with its parental monoclonal. PLoS One, 11 (3). pp. 1-14. e0152148. doi:10.1371/journal.pone.0152148 ISSN 1932-6203.
Bailey, Mark, Srivastava, Anjil, Conti, Lucio, Nelis, Stuart, Zhang, Cunjin, Florance, Hannah, Love, Andrew, Milner, Joel, Napier, R. (Richard), Grant, Murray R. and Sadanandom, Ari (2016) Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana. Journal of Experimental Botany, 67 (1). pp. 353-363. doi:10.1093/jxb/erv468 ISSN 0022-0957.
Quan, Wen-Dong, Pitto-Barry, Anaïs, Baker, Lewis A., Stulz, Eugen, Napier, R. (Richard), O'Reilly, Rachel K. and Stavros, Vasilios G. (2015) Retaining individualities : the photodynamics of self-ordering porphyrin assemblies. Chemical Communications, 52 (9). pp. 1938-1941. doi:10.1039/c5cc09095d ISSN 1359-7345.
Coe, Samuel, Pereira, Nicole, Geden, Joanna V., Clarkson, Guy J., Fox, David J., Napier, R. (Richard), Neve, Paul and Shipman, Michael (2015) Ring closing metathesis reactions of α-methylene-β-lactams : application to the synthesis of a simplified phyllostictine analogue with herbicidal activity. Organic & biomolecular chemistry, Volume 13 (Number 28). pp. 7655-7663. doi:10.1039/c5ob00890e ISSN 1477-0520.
Lee, Sarah C., Sundaram, Shanthy, Armitage, Lynne, Evans, John P., Hawkes, Tim, Kepinski, Stefan, Ferro, Noel and Napier, R. (Richard) (2014) Defining binding efficiency and specificity of auxins for SCFTIR1/AFB-Aux/IAA co-receptor complex formation. ACS Chemical Biology, Volume 9 (Number 3). pp. 673-682. doi:10.1021/cb400618m ISSN 1554-8929.
Tian, Faming, Greplová, Marta, Frébort, Ivo, Dale, Nicholas and Napier, R. (Richard) (2014) A highly selective biosensor with nanomolar sensitivity based on cytokinin dehydrogenase. PLoS One, Volume 9 (Number 3). Article number e90877. doi:10.1371/journal.pone.0090877 ISSN 1932-6203.
Conti, Lucio, Nelis, Stuart, Zhang, Cunjin, Woodcock, Ailidh, Swarup, Ranjan, Galbiati, Massimo, Tonelli, Chiara, Napier, R., Hedden, Peter, Bennett, Malcolm J. and Sadanandom, Ari (2014) Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin. Developmental Cell, Volume 28 (Number 1). pp. 102-110. doi:10.1016/j.devcel.2013.12.004 ISSN 1534-5807.
Abdul Kadir, Muhd K., Hines, Evor, Qaddoum, Kefaya, Collier, Rosemary, Dowler, Elizabeth, Grant, Wyn, Leeson, Mark S., Iliescu, Daciana, Subramanian, Arjunan, Richards, Keith, Merali, Yasmin and Napier, R. (2013) Food security risk level assessment : a fuzzy logic-based approach. Applied Artificial Intelligence, Volume 27 (Number 1). pp. 50-61. doi:10.1080/08839514.2013.747372 ISSN 0883-9514.
Calderón Villalobos, Luz Irina A, Lee, Sarah C., Oliveira, Cesar de, Ivetac, Anthony, Brandt, Wolfgang, Armitage, Lynne, Sheard, Laura B., Tan, Xu, Parry, Geraint, Mao, Haibin, Zheng, Ning, Napier, R. (Richard), Kepinski, Stefan and Estelle, Mark (2012) A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin. Nature Chemical Biology, Volume 8 (Number 5). pp. 477-485. doi:10.1038/nchembio.926 ISSN 1552-4450.
Kowalska, Marta, Tian, Faming, Šmehilová, Mária, Galuszka, Petr, Frébort, Ivo, Napier, R. (Richard) and Dale, Nicholas (2011) Prussian Blue acts as a mediator in a reagentless cytokinin biosensor. Analytica Chimica Acta, Vol.701 (No.2). pp. 218-223. doi:10.1016/j.aca.2011.06.018 ISSN 0003-2670.
Ghaffari, Reza, Zhang, Fu, Iliescu, Daciana, Hines, Evor, Leeson, Mark S. and Napier, R. (2011) Field asymmetric ion mobility spectrometry based plant disease detection : intelligent systems approach. In: Qahwaji, Rami, 1972- and Green, Roger, 1951- and Hines, Evor, 1957-, (eds.) Applied signal and image processing : multidisciplinary advancements. Hershey, PA: IGI Global, pp. 102-114. ISBN 9781609604776
Ghaffari, Reza, Zhang, Fu, Iliescu, Daciana, Hines, Evor, Leeson, Mark S. and Napier, R. (2011) The analysis of plant's organic volatiles compounds with electronic nose and pattern recognition techniques. In: Qahwaji, Rami, 1972- and Green, Roger, 1951- and Hines, Evor, 1957-, (eds.) Applied signal and image processing : multidisciplinary advancements. Hershey, PA: IGI Global, pp. 115-126. ISBN 9781609604776
Sadanandom, Ari and Napier, R. (Richard) (2010) Biosensors in plants. Current Opinion in Plant Biology, Vol.13 (No.6). pp. 736-743. doi:10.1016/j.pbi.2010.08.010 ISSN 1369-5266.
Ghaffari, Reza, Zhang, Fu, Iliescu, Daciana, Hines, Evor, Leeson, Mark S., Napier, R. and Clarkson, John P. (2010) Early detection of diseases in tomato crops : an electronic nose and intelligent systems approach. In: 2010 International Joint Conference on Neural Networks IJCNN 2010, Barcelona , 18-23 July 2010. Published in: IEEE International Conference on Neural Networks. Proceedings pp. 1-6. doi:10.1109/IJCNN.2010.5596535 ISSN 1098-7576.
Napier, R. (Richard) and Badescu, George O. (2009) A real-time biosensor for plant hormones. In: Annual Meeting of the Society-for-Experimental-Biology, Glasgow, Scotland, June 28-JUL 01, 2009. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.153A (No.2 Suppl. S). S212-S212. doi:10.1016/j.cbpa.2009.04.590 ISSN 1095-6433.
Carrier, David J., Abu Bakar, Norliza Tendot, Swarup, Ranjan, Callaghan, Richard, Napier, R. (Richard), Bennett, Malcolm J. and Kerr, Ian D. (2008) The binding of auxin to the Arabidopsis auxin influx transporter AUX1. Plant Physiology, Volume 148 (Number 1). pp. 529-535. doi:10.1104/pp.108.122044 ISSN 0032-0889.
Carrier, David J. , Bakar, Norliza Tendot Abu , Swarup, Ranjan , Callaghan, Richard , Napier, R. (Richard), Bennett, Malcolm J. and Kerr, Ian D. (2008) The binding of auxin to the Arabidopsis auxin influxtransporter, AUX1. Plant Physiology, Vol.147 . doi:10.1104/pp.108.122044 ISSN 0032-0889.
Hoyerova, Klara, Perry, Lucie, Hand, Paul, Lankova, Martina, Kocabek, Tomas, May, Sean T., Kottova, Jana, Paces, Jan, Napier, R. (Richard) and Zazimalova, Eva (2008) Functional characterization of PaLAX1, a putative auxin permease, in heterologous plant systems. Plant Physiology, Volume 146 (Number 3). pp. 1128-1141. doi:10.1104/pp.107.109371 ISSN 0032-0889.
Smith, Timothy R., Clark, Andrew J., Napier, R. (Richard), Taylor, Paul C., Thompson, Andrew J. and Marsh, Andrew (2007) Function and stability of abscisic acid acyl hydrazone conjugates by LC-MS2 of ex vivo samples. Bioconjugate Chemistry, Vol.18 (No.4). pp. 1355-1359. doi:10.1021/bc070069x ISSN 1043-1802.
Dilly, Suzanne J., Bell, Matthew J., Clark, Andrew J., Marsh, Andrew, Napier, R. (Richard), Sergeant, Martin J., Thompson, Andrew J. and Taylor, Paul C. (2007) A photoimmobilisation strategy that maximises exploration of chemical space in small molecule affinity selection and target discovery. Chemical Communications (Number 27). pp. 2808-2810. doi:10.1039/b704271j ISSN 1359-7345.
Dilly, Suzanne J., Beecham, Matthew P., Brown, Steven P., Griffin, John M., Clark, Andrew J., Griffin, Craig D., Marshall, Jacqueline, Napier, R. (Richard), Taylor, Paul C. and Marsh, Andrew (2006) Novel tertiary amine oxide surfaces that resist nonspecific protein adsorption. Langmuir, Vol.22 (No.19). pp. 8144-8150. doi:10.1021/la060743j ISSN 0743-7463.
Badescu, George O. and Napier, R. (Richard) (2006) Receptors for auxin : will it all end in TIRs? Trends in Plant Science, Volume 11 (Number 5). pp. 217-223. doi:10.1016/j.tplants.2006.03.001 ISSN 1360-1385.
Dilly, Suzanne J., Beecham, Matthew P., Brown, Steven P., Griffin, John M., Clark, Andrew J., Griffin, Craig D., Marshall, Jacqueline, Napier, R. (Richard), Taylor, Paul C. and Marsh, Andrew (2006) Novel tertiary amine oxide surfaces that resist non-specific protein adsorption. Langmuir, Vol.22 (No.19). pp. 8144-8150. doi:10.1021/la060743j ISSN 1520-5827.
Perrot‐Rechenmann, Catherine and Napier, R. (Richard) (2005) Auxins. Plant Hormones, Volume 72 . pp. 203-233. doi:10.1016/S0083-6729(04)72006-3 ISSN 0083-6729.
Napier, R. (Richard) (2004) Plant hormone binding sites. Annals of Botany, Volume 93 (Number 3). pp. 227-233. doi:10.1093/aob/mch041 ISSN 0305-7364.
Title | Funder | Award start | Award end |
---|---|---|---|
Warwick application TIAH | The Institute of Agriculture and Horticulture | 28 May 2024 | 10 Feb 2025 |
Developing a Knowledge Exchange Hub for the UK Fresh Produce sector | Royal Agricultural University | 01 Jul 2024 | 31 Dec 2024 |
CENTA Doctoral Training Partnership (led by Birmingham) | NERC | 01 Oct 2014 | 30 Sep 2023 |
BBSRC Mid-range Equipment ALERT 2021 Application - November 2021 | BBSRC | 01 Aug 2022 | 31 Jul 2023 |
Structural and functional characterization of the major auxin uptake carrier AUX1 protein (Chitra Joshi) | Medical and Life Sciences Research Fund | 01 Aug 2021 | 31 Mar 2022 |
Self-organising carbon nanosensors for imaging morphogenic gradients in plants | Leverhulme Trust | 01 Aug 2017 | 31 Aug 2021 |
H20 MC: Crystal structures of PIN proteins - CrysPINs. MSCA IF EF ST for Fellow Martin Kubes | European Commission | 01 Aug 2018 | 31 Jul 2020 |
Characterisation of aptamer sequences for the forensic detection of human sperm cells (James Gooch) | Royal Society of Chemistry | 26 Sep 2019 | 25 Feb 2020 |
Masters student placement agreement for Jill Stewart | SGS United Kingdom Limited | 03 Apr 2018 | 31 Jul 2018 |
Next generation auxins and anti-auxins : principles for binding and design | BBSRC | 03 Mar 2014 | 02 Mar 2017 |
GCRF-IAA Resistance to quinolates ? a computational biophysics approach | BBSRC | 01 Oct 2016 | 31 Dec 2016 |
BBSRC Industrial CASE Studentship (Craig Knight) Novel informed modelling approaches to invetigate the evolution and management of herbicide resistance in Alopecurus myosuroides | Bayer Crop Science | 03 Oct 2011 | 02 Oct 2015 |
CASE (DTG) Development of the Plant Ubiquitome as a Novel Crop Protection Strategy - Mark Bailey studentship (Ari Sadanandom now Durham) | Syngenta Seeds B.V | 01 Oct 2011 | 30 Sep 2014 |
Summer Vacation Grant - Biochemical Society | Biochemical Society | 16 Apr 2014 | 12 Sep 2014 |
Association of Commonwealth Universities Professional Fellowship - Dr Tripathi | Commonwealth Scholarship Commision in the UK | 10 Sep 2013 | 28 Feb 2014 |
Quantitative sensors for phytohormone signalling systems | BBSRC | 01 Aug 2011 | 31 Jul 2012 |
Efficient use of inputs in protected horticulture EUPHOROS | European Commission | 01 Mar 2008 | 29 Feb 2012 |
Research Support Grant for Dr Shanthy Sundaram | Commonwealth Scholarship Commision in the UK | 04 Feb 2011 | 31 Mar 2011 |
Understanding specificity in auxin perception | BBSRC | 01 Mar 2008 | 28 Feb 2011 |
National Science Week Awards: Hands-on Plants | RCUK | 09 Mar 2007 | 10 Mar 2007 |
UG teaching:
“Introduction to enzymes” in BS129, Physiology and Metabolism
“Measuring binding and molecular interactions” in BS219, Tools for Biochemical Discovery
“Bioethics for biotechnology” in BS365, Exploiting Innovation in Biology
I am developing a Y2 module on “Plants, People, Products and Places”
PGT teaching includes lectures on lodging and use of PGRs in broadfield crops and leadership of the “Research Project” module for EFS courses.
Final year UG project topics will include “alternative protein/dairy/milk technologies and markets” and other topical science subjects; “aptamers”; “nanoparticles in the terresphere”; “intrinsically-disordered proteins including Aux/IAA co-receptor proteins” and other plant biochemistry projects by discussion. I may be able to offer lab projects on the fate of polymer nanoparticles in Drosophila and/or mealworms.
I am happy to receive enquires about PG Research projects. Topics available are listed on my research pages, link above. Please contact me by email.