Structural Biology at Warwick
Subject: Structural Biology Symposium at Warwick - 15th Nov Zeeman Building- Room MS.03
Structural Biology Symposium at Warwick - 15th Nov Zeeman Building- Room MS.03
As part of an initiative to bring structural biologists at Warwick together, we are holding a ‘Structural Biology at Warwick’ Symposium’ on Wednesday November 15th 2023. The aim of the symposium is to showcase structural biology research carried out at Warwick and to provide early career researchers (PhD students, postdocs, technical professionals, new PIs) with an opportunity to share their work. We would like to invite you to this event and to encourage your group members or other colleagues to submit a talk title. Talks will be 15 minutes including questions. We will select talks based on scientific interest and to achieve a good balance of techniques and topics. Please register here to confirm your attendance. Lunch will be provided, please detail any dietary requirements.
Full Programme:
12pm Lunch, posters and meet the facilities
1pm Welcome and introduction to talks
1.10pm Debs Brotherton, Life Sciences
The Connexin Conundrum: Clarifying Cx26 with High Resolution Cryo-EM
1.25pm Rosalie Cresswell, Solid-state NMR group, Physics
Using 2D solid-state NMR to understand the molecular structure of the secondary cell wall of plants
1.40pm Basim R. Hussain, MAS-CDT and FT-ICR MS Group, Chemistry
Tandem Mass Spectrometry and Multimodal Fragmentation of Phosphatidylthreonine (PT) and Phosphatidylserine (PS) Species in A549 Human Adenocarcinoma Epithelial Cells
1.55pm Edgars Polovinkins Warwick A*STAR Research Attachment Programme, Medical School
How does zebrafish ybx1 bind to target RNAs: insights from structure and function
2.10pm Matthew Turner, Physics
The effect of membrane tension on membrane protein structure
2.25pm Tea break
2.50pm Amy Godfrey, Gibson Lab MRC Doctoral Training Partnership, Medical School
Structure, function and binding of the tail fibres from an extracellular contractile injection system
3.05pm Lona Alkhalaf, Chemistry
Structural basis for [1,3]-phosphate shift in bacterial hormone biosynthesis
3.20pm Jeremy Keown, Life Sciences
Using cryoEM to study RNA virus polymerase
3.35pm Peng Wang, Physics
Cryogenic Electron Ptychography: An Emerging Technique for Biological Imaging
3.50pm Short break
4pm Keynote lecture – Satish Nair
Title “Turning Linear Peptides into Constrained Drugs”
Abstract: Bacterial natural products represent one of the major avenues towards the discovery and development of novel drugs including antibiotics, antifungals, and anticancer agents. Ribosomally synthesized and post-translationally modified peptides (RiPPs) encompass a wide variety of chemical scaffolds with an array of biological activities. These compounds are synthesized as linear peptides on the ribosome and then undergo modifications that confers bioactivities. Our lab focuses on structural biological and biochemical studies of the enzymes involved in biosynthesis of various RiPPs. Our goal is to exploit the substrate tolerances of these enzymes and pathways to produce compounds new to nature.