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Publications

• Karina Calvopiña, Philip Hinchliffe, Jürgen Brem, Samar Johnson, Kate J. Heesom, Ricky Cain, Christopher T Lohans, Colin W. G. Fishwick, Christopher J. Schofield, James Spencer, Matthew B. Avison, Structural / mechanistic insights into the efficancy of non-classical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates. Mol. Microbiol., 2017, 106 (3), 492-504. DOI: 10.1111/mmi.13831

• Suzanne J. Dilly, Andrew J. Clark, Andrew Marsh, Daniel A. Mitchell, Ricky Cain, Colin W.G. Fishwick, Paul C. Taylor: A Chemical Genomics Approach to Drug Reprofiling in Oncology: Antipsychotic Drug Risperidone as a Potential Adenocarcinoma Treatment. Cancer Lett. 2017, 393, 16-21 DOI: 10.1016/j.canlet.2017.01.042

• Samuel T. Cahill, Ricky Cain, David Y. Wang, Christopher T. Lohans, David W. Wareham, Henry Oswin, Jabril Mohammed, James Spencer, Colin W. G. Fishwick, Michael A. McDonough, Christopher J. Schofield, Jürgen Brem: Cyclic boronates inhibit all classes of β-lactamases. Accepted to Antimicrob. Agents Chemother. 2017, 61 (4), e02260-16 DOI:10.1128/AAC.02260-16

Ricky Cain, Jürgen Brem, Samuel Cahill, Michael A. McDonough, Ian J. Clifton, James Spencer, Colin W. G. Fishwick, Christopher J. Schofield: Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat. Commun. 2016, 7, 12406. DOI: 10.1038/ncomms12406

• Martin McPhillie, Ricky Cain, Sarah Narramore, Colin W.G. Fishwick , Katie Simmons: Computational Methods to Identify New Antibacterial Targets. Chem. Biol. Drug Des., 2015, 85 (1), 22-29. DOI: 10.1111/cbdd.12385

Ricky Cain, Sarah Narramore, Martin McPhillie, Katie Simmons, Colin W.G. Fishwick: Applications of structure-based design to antibacterial drug discovery. Bioorg. Chem., 2014, 55 (1), 69-76. DOI: 10.1016/j.bioorg.2014.05.008

• Sander S. van Berkel, Jürgen Brem, Ricky Cain, Anna Rydzik, Ramya Salimraj, Colin W. G. Fishwick, Raymond J. Owens, Jim Spencer, Christopher J. Schofield: An Assay Platform for Clinically Relevant Metallo-β-Lactamase. J. Med. Chem., 2013, 56, 6945-6953. DOI: 10.1021/jm400769b