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Neglected Tropical Diseases

 

 Dr. Orin Courtenay's Research Group current members:

Dr Erin Dilger Entomologist / epidemiologist University of Warwick Erin.Dilger@warwick.ac.uk
Dr Juliana Figuerido da Costa Lima Molecular biologist Fiocruz-PE, Brazil jfcl@cpqam.fiocruz.br
Lidija Kravar-Garde Senior Research Technician University of Warwick L.Kravar-Garde@warwick.ac.uk
Leopoldo Costa Veterinarian UNESP, Brazil leopoldo.ancosta@gmail.com
Talita Branganca Veterinarian UNESP, Brazil tabraganca@hotmail.com
Hayley King Zoologist, PhD student University of Warwick Hayley.King@warwick.ac.uk
José Ferreira Marinho Júnior Public Health Zoologist, PhD student Fiocruz-PE, Brazil junior@cpqam.fiocruz.br
Lilian Rodas Entomologist, PhD student SUCEM, Brazil colerodas@gmail.com
Raquel Gonςalves Entomologist, PhD student University of Warwick ragonalves@yahoo.com.br

 

Leishmaniasis

Leishmania are vector-borne protozoan intracellular parasites causing disease in humans and sometimes dogs in 98 countries across 5 continents with an estimated 0.2-0.4 million, and 0.7-1.2 million, annual new cases of visceral and cutaneous leishmaniasis, respectively. More than 20 species of Leishmania cause disease in humans most with complex transmission cycles involving a diversity of zoonotic reservoirs and different sand fly vector species. The disease spectrum in humans includes simple cutaneous to disseminated or metastasised mucocutaneous lesions to life threatening visceral involvement. Against transmission, there are no human vaccines, animal culling is controversial and vector control is complex or/and predominantly unsustainable. However novel control methods are becoming available for field evaluation.

Current projects

 

Environmental Mycobacterium and bovine tuberculosis

Members of the Mycobacterium genus cause a range of diseases in animals and humans including bovine tuberculosis due to M. bovis that is one of the most economically largest animal health problems in the UK farming industry, and costing the tax payer over £500m in the past decade. The European badger is known to be involved in the transmission cycle in the UK and Ireland, and one route of transmission between these hosts is thought to be via environmental contamination with M. bovis. More generally, environmental reservoirs of pathogenic and immunomoderating Mycobacteria spp are poorly studied despite their suggested role in inhibiting human BCG efficacy.

Current Projects