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WCUS collaborates in new anti-cancer work, published in Nature Chemistry
New research published last week in Nature Chemistry demonstrates a novel highly oxidative Ir(iii) photocatalyst, which is phototoxic towards both normoxic and hypoxic cancer cells.This research was a large collaborative project between groups in China, Switzerland, France, and the UK. WCUS contributed time resolved phosphorescence data to the study, which demonstrated an extremely long phosphorescence lifetime of the photocatalyst, thus leading to a very high oxidation turn over number making it a very effective anti-cancer agent.
Targeted photoredox catalysis in cancer cells
Huaiyi Huang, Samya Banerjee, Kangqiang Qiu, Pingyu Zhang, Olivier Blacque, Thomas Malcomson, Martin J. Paterson, Guy J. Clarkson, Michael Staniforth, Vasilios G. Stavros, Gilles Gasser, Hui Chao & Peter J. Sadler
Nature Chemistry (Sept. 2019) [ ref ]
The role of symmetric functionalisation on photoisomerisation of a UV commercial chemical filter
J.M. Woolley, J.S. Peters, M.A.P. Turner, G.J. Clarkson, M.D. Horbury and V.G. Stavros
Phys. Chem. Chem. Phys. (2019) [ref]
Substituent position effects on sunscreen photodynamics: a closer look at methyl anthranilate
N. D. N. Rodrigues, N. Cole-Filipiak, M. A. P. Turner, K. Krokidi, G. L. Thornton, G. W. Richings, N. D. M. Hines and V. G. Stavros.
Chem. Phys. 515, 596-602 (2018) [ref]