Life Sciences News
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Understanding lung infections in patients with cystic fibrosis
For young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function. However there has recently been debate over the role S. aureus plays in CF lung disease. Dr Esther Sweeney, Dr Freya Harrison and colleagues have used a new model of CF lungs which could be used to make better decisions about future use of antibiotics.
Press Release (19 November 2020)
Chemical clues in leaves can reveal ash tree resistance to deadly disease
Dr John Sidda, Professor Murray Grant and colleagues, have identified a group of chemicals present in ash leaves which could be used as biomarkers to look for susceptibility or resistance to ADB.
Press Release (11 November 2020)
Genetic mutation may hold answers to controlled breathing
The relationship between the Cx26 gene and ability to regulate Carbon dioxide is to be explored by Professor Nick Dale thanks to a £686,956 grant, from the BBSRC.
Press Release (13 August 2020)
Natural way to boost crop yield to be explored by Warwick Scientists
An innovative way to increase plant yield naturally, reducing the need for expensive fertilisers is being explored by Dr Miriam Gifford, Dr Isabelle Carré and colleagues, thanks to a £492,343 grant from the BBSRC.
Press Release (12 August 2020)
Breakthrough in studying ancient DNA from Doggerland that separates the UK from Europe
Professor Robin Allaby and colleagues have achieved a number of innovative breakthroughs in analysing sedimentary ancient DNA to reconstruct an 8,150 year old environmental catastrophe in an area that is now covered by the North Sea.
Press Release(16 July 2020)
UKRI fellowships awarded to Life Sciences Academics
Two academics from Life Sciences have been awarded a UKRI Future Leader Fellowship.
- Dr Byron Carpenter for his project titled: Developing a synthetic signalling system capable of the precise spatial and temporal control of protein function in living cells.
- Dr Erin Connelly for her project: Datamining medieval medical texts for modern medicines.
The fellowship scheme is awarded to the best researchers in the UK, keeping research and innovation in the UK world class.
Warwick Researchers to provide COVID-19 Intervention Modelling for East Africa (CIMEA)
A £1m grant from the Wellcome Trust has enabled researchers to work with East African countries in their emergency preparations for COVID-19 as the pandemic spreads across Africa. Press Release
Professor James Nokes comments:
'We hope that by closely combining our efforts with in-country expertise in modelling, epidemiology, health economics and systems and vulnerability mapping we can develop models appropriate to each setting with results that will immediately feed into the policy making process to have the greatest impact.'
Microbial interactions in aquatic environments to be investigated
The microbes found in aquatic environments and their interactions will be investigated by Warwick researcher Professor Orkun Soyer, thanks to an investigator award from The Gordon and Betty Moore foundation.
Check your pulses
The Knowledge Centre look at research by Professor Eric Holub into new haricot bean varieties which are suitable for growing in the UK climate.
Read the article
The Vegetables of Christmas Future
If you think about a traditional Christmas dinner, there’s turkey with pigs in blankets, or maybe you prefer a nut roast. But the rest is vegetables. A large proportion of our plate should be covered in vegetables, and the standard winter varieties, like carrots and sprouts, are grown very successfully in the UK.
But will this always be the case? Climate change is bringing with it new challenges as well as making known pests and diseases more difficult to tackle. Scientists at Warwick's Crop Centre, are working to understand the pests and diseases of the some of the UK’s major crops and developing, using traditional plant breeding and genetic expertise, new resistant varieties.
Going viral: What are bacteriophages and how can they help us?
Antibiotics are going to stop working. Bacteria are developing resistance to the drugs we have to treat them and there is no doubt that without action getting an infection or having surgery is going to get a lot more risky. With a global health crisis on our hands, scientists across the world are now trying to find alternatives to the drugs which have kept us alive for the past decade.
One possible solution is the use of bacteriophages.
Dr Antonia Sagona is working on understanding how phages fight infections.
The real Frozen: What can we do with ice?
Dr Hendrik Schafer and colleagues are looking at the microbial cycling of trace gases in sea ice as part of an international research programme called MOSAiC.
Read Knowledge Centre article
Academic job opportunity: Associate Professor or Professor of Infection Microbiology
Applications are invited for an Associate Professor or Professor of Infection Microbiology to join our vibrant research and teaching community in the School of Life Sciences.
We particularly encourage applications from candidates who complement existing strengths in the School and who will lead research in the areas of laboratory based antimicrobial resistance and anti-infective discovery, the human microbiome, host-pathogen interactions and immunology, microbial genetics and chemical biology approaches to address human and animal infection.
Great Wall Symposium 2019
Bacterial cell biology researchers from across the world gathered at The Pasteur institute in Paris at the end of September to attend the 6th biennial Great Wall symposium organised by Professor David Roper and Professor Ivo Boneca (Pasteur). This three day meeting on all aspects of bacterial cell wall biosynthesis was attended by just under 200 interdisciplinary researchers on all aspects of bacterial cell wall microbiology.
Dr Adrian Lloyd from SLS provided an invited talk on his recently submitted research on 'Substrate and stereochemical control of cell wall crosslinking by E. coli PBP1B' as well as a posters from a number of Warwick PhD students from SLS and WMS.
Videos from First Labcut Workshop
Funded by the Wellcome Trust and Warwick Quantitative Biomedicine Programme (WQBP), LabCut is a science film workshop run by SynBio CDT PhD students Cansu Kuey, Charlotte Gruender and Patrick Capel. The five films created during the inaugural workshop are now available to be viewed and will be screened during the British Science Festival in September. Find out more
National livestock movement bans may prove economically damaging
New research led by Dr Mike Tildesley has pioneered an economic perspective on controlling livestock diseases. Focusing on Foot and Mouth Disease (FMD), bovine TB (bTB) and bluetongue virus (BTV), the researchers draw striking conclusions about the role of movement bans in controlling an outbreak.
Phenom UK 2019
On Monday 22 July, researchers from the University of Sheffield, Rothamsted Research and the University of Nottingham attended a networking event at the University of Warwick Wellesbourne campus. The event was organised by Dr Beatriz Lagunas and sponsored by Phenom UK (‘Technology Touching Life programme funded jointly by BBSRC/EPSRC/MRC). In the morning, visitors enjoyed a guided tour around the field research facility including the pathogen quarantine fields, insect pest trial area, the low nutrient field, and the main rotation fields for irrigated trials. In the afternoon, a round table discussion focused on the challenges of field-based phenotyping.
The breadth of expertise amongst participants allowed discussion of ideas for relating aerial spectral imaging of the crop canopy with below-ground differences in soil nutrient/root/microbe interactions. The consensus was that pilot data is needed in a specific crop from small-scale controlled experiments to identify disease signature wavelengths and then move to field phenotyping based, for example using drone-based imaging in collaboration with both the University of Sheffield and Rothamsted Research. The PhenomUK website will provide a useful forum for further discussions. All Warwick people interested in following up the discussions are encouraged to do it through the Plant & Crop Science Theme and to register at the Phenom UK website.
Phenom UK networking visit attendants standing in a field of haricot beans (from left to right):
Craig Sturrock (U. of Nottingham), Patrick Schäfer (U. of Warwick), Rob Lillywhite (U. of Warwick), Stephen A. Rolfe (U. of Sheffield), Graham Teakle (U. of Warwick), Gabriel Castrillo (U. of Nottingham), John Clarkson (U. of Warwick), Beatriz Lagunas (U. of Warwick), Guilhem Reyt (U. of Nottingham), Sally Mann (U. of Warwick), Malcolm Hawkesford (Rothamsted Research), Alexander McCormack (U. of Warwick), Tim Mauchline (Rothamsted Research), Rosemary Collier (U. of Warwick), Joost H.M. Stassen (U. of Sheffield), Rory Hayden (U. of Nottingham) and Eric Holub (U. of Warwick).
A cure for the common cold?
Did you know that SLS researchers have been leading work to find cures for the common cold and influenza?
Listen as Professor Nigel Dimmock discusses his career and his new antiviral research on the BBC.
Download or listen online bbc.in/2GA7W74
When and how did we first start to domesticate wild plants?
Professor Robin Allaby talks to CrowdScience on the BBC World Service and explains all.
Listen to bbc.in/2JV7jpV (Interview starts at approx 5:28).
Bacteria such as E. coli detected in minutes by new technology
Dr Munehiro Asally, Dr James Stratford and colleagues, showed that bioelectrical signals from bacteria can be used to rapidly determine if they are alive or dead.
The findings offer a new technology which detects live bacteria in minutes instead of waiting for lab-test results which can take days.
When 'zapped' with an electrical field, live bacteria absorb dye molecules, causing the cells to light up and allowing them to be counted easily.
This rapid technique can detect antibiotic-resistant bacteria.