Principal Investigators
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Molecular mechanisms regulating eukaryotic cytokinesis
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The impact of human metabolism on development of obesity and strategies to prevent and manage obesity and diabetes |
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The molecular basis of obesity and diabetes |
The mechanisms of reproduction in mammals |
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How eukaryotic DNA is packaged and organised within the cell |
The development of new tests and therapies to prevent implantation failure and miscarriage |
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The force generating mechanisms of kinesins and microtubules |
The interplay between circadian clocks, diseases and pharmacotherapy |
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The use of cutting-edge techniques to explore the role of unconventional T cells in the immune surveillance of the human body |
Understanding flagellum function in protozoan parasites and humans |
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Investigating the role of the innate immune system and host-microbiota interactions in women’s reproductive health disorders. |
Cardiac arrhythmias; atrial fibrillation, ventricular tachycardia; ablation, complex mapping technologies
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Stress hormones and homeostatic adaptive responses in feto-maternal pathophysiology |
Investigating disease mechanisms in the chronic inflammatory disorder endometriosis |
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Understanding the establishment and embryonic development of the mammalian germline |
Vascular surgery, pathophysiology of reperfusion injury in vascular surgery; vascular tissue engineering and regenerative medicine |
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Indicators of oocyte and embryo development |
How the cells of our immune system are capable of discriminating between healthy and infected cells
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The molecular and physical principles that govern processes at the plasma membrane of cells |
How the protozoan parasite Trypanosoma cruzi causes Chagas disease |
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How cells and embryos ensure error-free chromosome segregation |
Membrane organisation and dynamics at cellular interfaces |
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The fundamental mechanisms that regulate the cell division cycle |
The mechanism of cytokinesis |
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Gene regulatory networks, regulatory sequence analysis, multi-omic and single-cell data analysis |
The development of novel materials for medical application |
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Understanding and preventing pregnancy loss |
Metabolic and endocrine diseases, including obesity, diabetes and polycystic ovary syndrome in women, and their related heart problems |
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How migrating cells talk to their immediate and distant neighbours using both chemical and mechanical signals |
Replication, detection and diagnosis of RNA viruses |
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Mitosis and membrane trafficking |
Development and differentiation of embryonic progenitors and adult stem cells, and the molecular mechanisms underlying these processes
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Deciphering the biochemical and biomechanical processes that shape organs |
How molecular mobility and interaction shape biological organisation and function across scales |
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The crosstalk between cell and tissue-scale mechanics and biochemical signalling to regulate developmental programs and cellular mechanisms in the embryo |
Mechanisms by which neuroendocrine, autonomic and behavioural responses to disturbances in energy levels are integrated. |
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Mechanisms that generate specific microtubule arrays in polarised cells |
Viral evolution, pathogenesis and vaccine development |
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Understanding how bacteria invade and survive our host defence systems |
Understanding the molecular mechanisms and ultimately exploiting natural bacterial toxin systems for biotechnology purposes |
Mohan Balasubramanian
Thomas Barber
Claire Bastie
Robert Dallmann
Tarvinder Dhanjal
Dimitris Grammatopoulos
Erin Greaves
Geraldine Hartshorne
John James
Masanori Mishima
Sascha Ott
Sebastien Perrier
Nicole Robb
Stephen Royle
Karuna Sampath
Timothy Saunders
Michael Smutny
Nick Waterfield