Principal Investigators
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Molecular mechanisms regulating eukaryotic cytokinesis
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The impact of human metabolism on development of obesity and strategies to prevent and manage obesity and diabetes |
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The molecular basis of obesity and diabetes |
The mechanisms of reproduction in mammals |
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How eukaryotic DNA is packaged and organised within the cell |
The development of new tests and therapies to prevent implantation failure and miscarriage |
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The force generating mechanisms of kinesins and microtubules |
The interplay between circadian clocks, diseases and pharmacotherapy |
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The use of cutting-edge techniques to explore the role of unconventional T cells in the immune surveillance of the human body |
Understanding flagellum function in protozoan parasites and humans |
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Investigating the role of the innate immune system and host-microbiota interactions in women’s reproductive health disorders. |
Cardiac arrhythmias; atrial fibrillation, ventricular tachycardia; ablation, complex mapping technologies
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Stress hormones and homeostatic adaptive responses in feto-maternal pathophysiology |
Investigating disease mechanisms in the chronic inflammatory disorder endometriosis |
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Understanding the establishment and embryonic development of the mammalian germline |
Vascular surgery, pathophysiology of reperfusion injury in vascular surgery; vascular tissue engineering and regenerative medicine |
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Indicators of oocyte and embryo development |
How the cells of our immune system are capable of discriminating between healthy and infected cells
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How mechanosensing at the interface regulates neuronal development |
The molecular and physical principles that govern processes at the plasma membrane of cells |
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How the protozoan parasite Trypanosoma cruzi causes Chagas disease |
How cells and embryos ensure error-free chromosome segregation |
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Membrane organisation and dynamics at cellular interfaces |
The fundamental mechanisms that regulate the cell division cycle |
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The mechanism of cytokinesis |
Developing and application of advanced optical and computational tools to study cardiac electrophysiology and arrhythmias |
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Gene regulatory networks, regulatory sequence analysis, multi-omic and single-cell data analysis |
The development of novel materials for medical application |
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Understanding and preventing pregnancy loss |
Metabolic and endocrine diseases, including obesity, diabetes and polycystic ovary syndrome in women, and their related heart problems |
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How migrating cells talk to their immediate and distant neighbours using both chemical and mechanical signals |
Replication, detection and diagnosis of RNA viruses
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Mitosis and membrane trafficking |
Deciphering the biochemical and biomechanical processes that shape organs |
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Deciphering the biochemical and biomechanical processes that shape organs
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How molecular mobility and interaction shape biological organisation and function across scales
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Physical modelling of morphogenesis, bioelectricity |
The crosstalk between cell and tissue-scale mechanics and biochemical signalling to regulate developmental programs and cellular mechanisms in the embryo |
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Mechanisms that generate specific microtubule arrays in polarised cells |
Viral evolution, pathogenesis and vaccine development |
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Understanding how bacteria invade and survive our host defence systems |
Understanding the molecular mechanisms and ultimately exploiting natural bacterial toxin systems for biotechnology purposes |
Mohan Balasubramanian
Thomas Barber
Claire Bastie
Robert Dallmann
Tarvinder Dhanjal
Dimitris Grammatopoulos
Erin Greaves
Geraldine Hartshorne
John James
Masanori Mishima
Timothy Saunders
Falk Schneider
